1 research outputs found
Choosing orientation: influence of cargo geometry and ActA polarization on actin comet tails
ETOC: We reconstitute actin-based motility using ellipsoidal particles mimicking the rod shape of Listeria monocytogenes and systematically analyze bead motile behaviors. By combining features of elastic propulsion and tethered-ratchet actin-polymerization models, we can explain our observations with a comprehensive new biophysical model