An image from the “Atlas for Stereotaxy of the Human Brain”: Schaltenbrand and Wahren, Plate 54 [25] showing a the stimulation target as red marker overlying the anteromedial pallidum on an axial brain slice at 3.5 mm below the AC/PC line.

<p>An image from the “Atlas for Stereotaxy of the Human Brain”: Schaltenbrand and Wahren, Plate 54 <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0104926#pone.0104926-Schaltenbrand1" target="_blank">[25]</a> showing a the stimulation target as red marker overlying the anteromedial pallidum on an axial brain slice at 3.5 mm below the AC/PC line.</p

Change in Total Yale Global Tic Severity Score (TYGTTS) at different time points pre and post-DBS.

<p>Bold line indicates the mean of the scores. Mean scores were only displayed when more than 3 data points were present. There was a downward trend or no change in the mean scores after 23 months.</p

Summary of individual patient characteristics.

1<p>including botulinum toxin.</p