Brexit and the abuse of history

When, tonight, the bells will toll the eleventh hour, thereis hope that at least one part of the painful Brexit saga will come to an end: the tedious abuse of history that has hounded us every step of the way. (It feels personal to lawyers. We have to use history all the time –to understand precedent, to evaluate the legal meaning of State practice and so forth. But we know full well that a historical analogy which does not work means we lose the argument)

Beach impact study, Padre Island National Seashore

Prepared for Office of Natural Science, Southwest Region, National Park Service, under contract CX70005044830 April 1976Vegetative differences between heavily and very lightly trafficked beaches show that more beach traffic correlates with quantitative decreases in variety and density of plants and with declines of grasses relative to forbs. The vegetated portions of all beaches continue to grow in volume. However, this is at the expense of the more seaward (more trafficked) parts of the beaches and has lead to overall loss of total beach volume except where vehicular traffic is prohibited. The very lightly trafficked beach is the only study site wherein the entire beach to mean sea level has grown. The effect of these trends on resistance to storm surge erosion remains to be tested.Marine Scienc

Roles of fission yeast tea1p in the localization of polarity factors and in organizing the microtubular cytoskeleton

The cylindrical shape of the fission yeast cell is generated by linear polarized growth from its cell ends. Using immunofluorescence and live imaging microscopy, we have investigated the roles of the cell end marker tea1p in generating linear polarized growth. We found that tea1p is primarily transported on plus ends of microtubules from the vicinity of the nucleus to the cell ends, and that its movement near the nucleus is independent of the kinesin tea2p. Deletion analysis identified a coiled-coil domain in tea1p essential for its retention at cell ends, and demonstrated that tea1p exerts different functions dependent on its location. On the tips of microtubules, tea1p prevents the curling of microtubules around the cell ends, whereas it is required for maintaining linear cell growth and for retention of polarity factors such as the Dyrk kinase pom1p, the CLIP170-like tip1p, and tea2p at the cell ends. We propose that tea1p has roles in organizing the microtubule cytoskeleton on the tips of microtubules, and in the retention of factors at the cell ends necessary for the cell to grow in a straight line

The law of diplomatic asylum:A contextual approach

This Article will deal with the conduct of diplomatic missions and their agents; it will primarily address the question of whether they are entitled to grant asylum on diplomatic premises. That is not the same as the question whether a refugee may be entitled to asylum on mission premises— the individual asylum seeker may be subject to a different set of norms

Why Brexit spells trouble for workers’ rights

When you try to figure out what the EU has ever done for workers’ rights, the internet can be a confusing place. Opinions vary widely, depending on political persuasion, and the resulting picture has a Dickensian tinge to it: it is the best of Unions, it is the worst of Unions

Neurovascular anatomy around the knee: Relevance of the dangers of self-drilling external fixator pin tips.

INTRODUCTION: With external fixation of the femur and tibia, iatrogenic injury to neurovasculature from self-drilling tips of fixation pins is an important consideration in pin placement. Precise knowledge of the neurovascular anatomy in the distal femur and proximal tibia is important to limit potential pin misplacement. METHOD: Six pin placement sites on six cadaveric legs were used in accordance with current placement techniques. After pin placement, the soft tissue around each pin was dissected and the distances between the pin tips and the surrounding neurovasculature were measured. RESULTS: The resultant data allow for a description of safe and unsafe corridors which can be used for external fixator pin placement. Safe sagittal insertion into the distal femur should consist of two pins: (1) 90 mm ± proximal from the proximal pole of the patella and 3 mm ± medially, (2) 55 mm ± proximal from the proximal pole of the patella and 2 mm ± laterally. Safe coronal insertion into the distal femur should consist of two pins: (1) 30 mm ± proximal to the lateral epicondyle, (2) 100 mm ± proximal to the lateral epicondyle. Safe proximal tibial pin placement should consist of two pins and be placed at an oblique angle: (1) 20 mm ± distal to the tibial tuberosity and 2 mm ± medially, (2) 55 mm ± distal to the tibial tuberosity and 2 mm ± medially. DISCUSSION: This study forms an investigation into the safe areas for placement of external fixator pins, within the distal femur and proximal tibia, specifically, detailing the best practice for pin placement in relation to the tips of the external fixation pins

Drivers of CO2 emissions from electricity generation in the European Union 2000–2015

Carbon emissions from electricity generation in the EU have dropped from 1198 MtCO2 in 2000 to 970 MtCO2 in 2015, after an initial increase to 1304

In vivo testing of a bioabsorbable magnesium alloy serving as total ossicular replacement prostheses

Magnesium alloys have been investigated in different fields of medicine and represent a promising biomaterial for implants due to characteristics like bioabsorbability and osteoinduction. The objective of this study was to evaluate the usability of magnesium as implant material in middle ear surgery. Magnesium implants were placed into the right middle ear of eighteen New Zealand White rabbits. Nine animals were euthanized after four weeks and nine animals after three month. The petrous bones were removed and embedded in epoxy resin. The specimens were then polished, stained and evaluated with the aid of a light microscope. The histological examination revealed a good biocompatibility. After four weeks, a beginning corrosion of the implant's surface and low amount of trabecular bone formation in the area of the stapes base plate was observed. A considerable degradation of implants and obvious bone formation was found three month after implantation. The magnesium alloy used in the present study partly corroded too fast, so that a complete bone reconstruction could not be established in time. The increased osteoinduction on the stapes base plate resulted in a tight bone-implant bonding. Thus, a promising application of magnesium could be a coating of biomaterials in order to improve the bony integration of implants. © The Author(s) 2012 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav