1,528 research outputs found
AGRICULTURAL AND FOREST LANDUSE CHANGES, AND THE ENVIRONMENTAL KUZNETS CURVE FOR DEFORESTATION: AN INTERTEMPORAL DYNAMIC EQUILIBRIUM
This study is an investigation of the process of land conversion from forest to agricultural production, and assessing the factors affecting the process. We also analyze the conditions that would ultimately lead to the EKC type of relationship between deforestation and societal income in an economy.Land Economics/Use,
Microparticles-Mediated Vascular Inflammation and its Amelioration by Antioxidant Activity of Baicalin.
Microparticles (MPs) are extracellular vesicles (0.1-1.0 μm in size), released in response to cell activation or apoptosis. Endothelial microparticles (EC-MP), vascular smooth muscle cell microparticles (VSMC-MP), and macrophage microparticles (MØ-MP) are key hallmarks of atherosclerosis progression. In our current study, we investigated the potent antioxidant activity of baicalin to ameliorate MP-induced vascular smooth muscle cell (VSMC) dysfunction and endothelial cell (EC) dysfunction, as well as the production of inflammatory mediators in macrophage (RAW264.7). In our study, baicalin suppressed the apoptosis, reactive oxygen species (ROS) generation, NO production, foam cell formation, protein expression of inducible nitric oxide synthase and cyclooxygenase-2 in MØ-MP-induced RAW264.7. In addition, VSMC migration induced by VSMC-MP was dose-dependently inhibited by baicalin. Likewise, baicalin inhibits metalloproteinase-9 expression and suppresses VSMC-MP-induced VSMC proliferation by down-regulation of mitogen-activated protein kinase and proliferating cell nuclear antigen protein expressions. Baicalin also inhibited ROS production and apoptosis in VSMC. In EC, the marker of endothelial dysfunction (endothelial senescence, upregulation of ICAM, and ROS production) induced by EC-MP was halted by baicalin. Our results suggested that baicalin exerts potent biological activity to restore the function of EC and VSMC altered by their corresponding microparticles and inhibits the release of inflammation markers from activated macrophages
AN ANALYSIS OF COST EFFECTIVE MANAGEMENT PRACTICES TO MANAGE WATER POLLUTION PROBLEM: A CASE OF TOBESOFKEE CREEK,GEORGIA
A cost minimization model was used to find the minimum cost and environmental friendly management practices(MCEFMP). Use of MCEFMP in cattle production seems to be the most cost effective means of reducing water pollution with a marginal cost of $1200 in comparison to use of MCEFMP on other agricultural operations.Environmental Economics and Policy,
Arp 65 interaction debris: massive HI displacement and star formation
Context: Pre-merger interactions between galaxies can induce significant
changes in the morphologies and kinematics of the stellar and ISM components.
Large amounts of gas and stars are often found to be disturbed or displaced as
tidal debris. This debris then evolves, sometimes forming stars and
occasionally tidal dwarf galaxies. Here we present results from our HI study of
Arp 65, an interacting pair hosting extended HI tidal debris. Aims: In an
effort to understand the evolution of tidal debris produced by interacting
pairs of galaxies, including in situ star and tidal dwarf galaxy formation, we
are mapping HI in a sample of interacting galaxy pairs. The Arp 65 pair is one
of them. Methods: Our resolved HI 21 cm line survey is being carried out using
the Giant Metrewave Radio Telescope (GMRT). We used our HI survey data as well
as available SDSS optical, Spitzer infra-red and GALEX UV data to study the
evolution of the tidal debris and the correlation of HI with the star-forming
regions within it. Results: In Arp 65 we see a high impact pre-merger
interaction involving a pair of massive galaxies (NGC 90 and NGC 93) that have
a stellar mass ratio of ~ 1:3. The interaction, which probably occurred ~ 1.0
-- 2.5 10 yr ago, appears to have displaced a large fraction of
the HI in NGC 90 (including the highest column density HI) beyond its optical
disk. We also find extended ongoing star formation in the outer disk of NGC 90.
In the major star-forming regions, we find the HI column densities to be ~ 4.7
10 cm or lower. But no signature of star formation was
found in the highest column density HI debris, SE of NGC 90. This indicates
conditions within the highest column density HI debris remain hostile to star
formation and it reaffirms that high HI column densities may be a necessary but
not sufficient criterion for star formation.Comment: Accepted in A&
Relationship between vaccination and nutritional status in children: Analysis of recent demographic and health surveys
BACKGROUND A body of evidence suggests that vaccines support the development of the immune system and also improve overall health. OBJECTIVE To study the effect of the complete basic vaccination schedule (Bacille Calmette-Guerin, i.e., BCG; measles; polio 3; and Diphtheria, Tetanus toxoids, and Pertussis, i.e., DTP3) on nutritional status of children under 2 years of age. METHODS Recent DHS data from 16 countries conducted after 2013 were used. After a bivariate descriptive analysis, a logistic regression analysis was conducted to predict the likelihood of underweight, stunting, and wasting by immunization status. A combined odds ratio was computed and adjusted for background variables. RESULTS A significantly higher prevalence of underweight was found among children with incomplete vaccination schedules in seven countries. Similarly, wasting and stunting were frequently observed in under-vaccinated children in four countries. Moreover, logistic regression adjusted for background variables revealed a relation between incomplete vaccination and underweight in Angola, Chad, and Guatemala (95% CI lower bound > 1). Combining data of all countries, underweight (adjusted Odds Ratio, aOR 1.21, 95% CI 1.11-1.31), wasting (aOR 1.18, 95% CI 1.05-1.33), and stunting (aOR 1.07, 95% CI 1.00-1.14) were associated with poor vaccination status. The overall effect was consistent with both sexes except the results for wasting for females and stunting for males, though insignificant. CONTRIBUTION To our knowledge, this is the first paper assessing the relation between vaccination and nutritional status at a multi-country level with a huge dataset. Our analysis suggests a poor nutritional status in children with an incomplete vaccination schedule
Fluorescent Calcium Imaging and Subsequent In Situ Hybridization for Neuronal Precursor Characterization in Xenopus laevis
Spontaneous intracellular calcium activity can be observed in a variety of cell types and is proposed to play critical roles in a variety of physiological processes. In particular, appropriate regulation of calcium activity patterns during embryogenesis is necessary for many aspects of vertebrate neural development, including proper neural tube closure, synaptogenesis, and neurotransmitter phenotype specification. While the observation that calcium activity patterns can differ in both frequency and amplitude suggests a compelling mechanism by which these fluxes might transmit encoded signals to downstream effectors and regulate gene expression, existing population-level approaches have lacked the precision necessary to further explore this possibility. Furthermore, these approaches limit studies of the role of cell-cell interactions by precluding the ability to assay the state of neuronal determination in the absence of cell-cell contact. Therefore, we have established an experimental workflow that pairs time-lapse calcium imaging of dissociated neuronal explants with a fluorescence in situ hybridization assay, allowing the unambiguous correlation of calcium activity pattern with molecular phenotype on a single-cell level. We were successfully able to use this approach to distinguish and characterize specific calcium activity patterns associated with differentiating neural cells and neural progenitor cells, respectively; beyond this, however, the experimental framework described in this article could be readily adapted to investigate correlations between any time-series activity profile and expression of a gene or genes of interest
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