The Design and Implementation of a High-Performance Log-Structured RAID System for ZNS SSDs

Zoned Namespace (ZNS) defines a new abstraction for host software to flexibly manage storage in flash-based SSDs as append-only zones. It also provides a Zone Append primitive to further boost the write performance of ZNS SSDs by exploiting intra-zone parallelism. However, making Zone Append effective for reliable and scalable storage, in the form of a RAID array of multiple ZNS SSDs, is non-trivial since Zone Append offloads address management to ZNS SSDs and requires hosts to dedicatedly manage RAID stripes across multiple drives. We propose ZapRAID, a high-performance log-structured RAID system for ZNS SSDs by carefully exploiting Zone Append to achieve high write parallelism and lightweight stripe management. ZapRAID adopts a group-based data layout with a coarse-grained ordering across multiple groups of stripes, such that it can use small-size metadata for stripe management on a per-group basis under Zone Append. It further adopts hybrid data management to simultaneously achieve intra-zone and inter-zone parallelism through a careful combination of both Zone Append and Zone Write primitives. We evaluate ZapRAID using microbenchmarks, trace-driven experiments, and real-application experiments. Our evaluation results show that ZapRAID achieves high write throughput and maintains high performance in normal reads, degraded reads, crash recovery, and full-drive recovery.Comment: 29 page

Influence of hand position on the near-effect in 3D attention

Voluntary reorienting of attention in real depth situations is characterized by an attentional bias to locations near the viewer once attention is deployed to a spatially cued object in depth. Previously this effect (initially referred to as the ‘near-effect’) was attributed to access of a 3D viewer-centred spatial representation for guiding attention in 3D space. The aim of this study was to investigate whether the near-bias could have been associated with the position of the response-hand, always near the viewer in previous studies investigating endogenous attentional shifts in real depth. In Experiment 1, the response-hand was placed at either the near or far target depth in a depth cueing task. Placing the response-hand at the far target depth abolished the near-effect, but failed to bias spatial attention to the far location. Experiment 2 showed that the response-hand effect was not modulated by the presence of an additional passive hand, whereas Experiment 3 confirmed that attentional prioritization of the passive hand was not masked by the influence of the responding hand on spatial attention in Experiment 2. The pattern of results is most consistent with the idea that response preparation can modulate spatial attention within a 3D viewer-centred spatial representation

A Chinese Chan-Based Mind-Body Intervention Improves Sleep on Patients with Depression: A Randomized Controlled Trial

Sleep disturbance is a common problem associated with depression, and cognitive-behavioral therapy (CBT) is a more common behavioral intervention for sleep problems. The present study compares the effect of a newly developed Chinese Chan-based intervention, namely Dejian mind-body intervention (DMBI), with the CBT on improving sleep problems of patients with depression. Seventy-five participants diagnosed with major depressive disorder were randomly assigned to receive 10 weekly sessions of CBT or DMBI, or placed on a waitlist. Measurements included ratings by psychiatrists who were blinded to the experimental design, and a standardized questionnaire on sleep quantity and quality was obtained before and after the 10-week intervention. Results indicated that both the CBT and DMBI groups demonstrated significantly reduced sleep onset latency and wake time after sleep onset (effect size range = 0.46–1.0, P ≤ 0.05) as compared to nonsignificant changes in the waitlist group (P > 0.1). Furthermore, the DMBI group, but not the CBT or waitlist groups, demonstrated significantly reduced psychiatrist ratings on overall sleep problems (effect size = 1.0, P = 0.00) and improved total sleep time (effect size = 0.8, P = 0.05) after treatment. The present findings suggest that a Chinese Chan-based mind-body intervention has positive effects on improving sleep in individuals with depression

Design of the Subpopulations and Intermediate Outcome Measures in COPD (SPIROMICS) AIR Study.

IntroductionPopulation-based epidemiological evidence suggests that exposure to ambient air pollutants increases hospitalisations and mortality from chronic obstructive pulmonary disease (COPD), but less is known about the impact of exposure to air pollutants on patient-reported outcomes, morbidity and progression of COPD.Methods and analysisThe Subpopulations and Intermediate Outcome Measures in COPD (SPIROMICS) Air Pollution Study (SPIROMICS AIR) was initiated in 2013 to investigate the relation between individual-level estimates of short-term and long-term air pollution exposures, day-to-day symptom variability and disease progression in individuals with COPD. SPIROMICS AIR builds on a multicentre study of smokers with COPD, supplementing it with state-of-the-art air pollution exposure assessments of fine particulate matter, oxides of nitrogen, ozone, sulfur dioxide and black carbon. In the parent study, approximately 3000 smokers with and without airflow obstruction are being followed for up to 3 years for the identification of intermediate biomarkers which predict disease progression. Subcohorts undergo daily symptom monitoring using comprehensive daily diaries. The air monitoring and modelling methods employed in SPIROMICS AIR will provide estimates of individual exposure that incorporate residence-specific infiltration characteristics and participant-specific time-activity patterns. The overarching study aim is to understand the health effects of short-term and long-term exposures to air pollution on COPD morbidity, including exacerbation risk, patient-reported outcomes and disease progression.Ethics and disseminationThe institutional review boards of all the participating institutions approved the study protocols. The results of the trial will be presented at national and international meetings and published in peer-reviewed journals

Supersymmetry and homogeneity of M-theory backgrounds

We describe the construction of a Lie superalgebra associated to an arbitrary supersymmetric M-theory background, and discuss some examples. We prove that for backgrounds with more than 24 supercharges, the bosonic subalgebra acts locally transitively. In particular, we prove that backgrounds with more than 24 supersymmetries are necessarily (locally) homogeneous.Comment: 19 pages (Erroneous Section 6.3 removed from the paper.

Organization of Block Copolymers using NanoImprint Lithography: Comparison of Theory and Experiments

We present NanoImprint lithography experiments and modeling of thin films of block copolymers (BCP). The NanoImprint lithography is used to align perpendicularly lamellar phases, over distances much larger than the natural lamellar periodicity. The modeling relies on self-consistent field calculations done in two- and three-dimensions. We get a good agreement with the NanoImprint lithography setups. We find that, at thermodynamical equilibrium, the ordered BCP lamellae are much better aligned than when the films are deposited on uniform planar surfaces

Searches for Long Lived Neutral Particles

An intriguing possibility for TeV scale physics is the existence of neutral long lived particles (LOLIPs) that subsequently decay into SM states. Such particles are many cases indistinguishable from missing transverse energy (MET) at colliders. We propose new methods to search for these particles using neutrino telescopes. We study their detection prospects, assuming production either at the LHC or through dark matter (DM) annihilations in the Sun and the Earth. We find that the sensitivity for LOLIPs produced at the LHC is limited by luminosity and detection energy thresholds. On the other hand, in the case of DM annihilation into LOLIPs, the sensitivity of neutrino telescopes is promising and may extend beyond the reach of upcoming direct detection experiments. In the context of low scale hidden sectors weakly coupled to the SM, such indirect searches allow to probe couplings as small as 10^-15.Comment: 22 pages, 6 figure

Variations of Little Higgs Models and their Electroweak Constraints

We calculate the tree-level electroweak precision constraints on a wide class of little Higgs models including: variations of the Littlest Higgs SU(5)/SO(5), SU(6)/Sp(6), and SU(4)^4/SU(3)^4. By performing a global fit to the precision data we find that for generic regions of the parameter space the bound on the symmetry breaking scale f is several TeV, where we have kept the normalization of f constant in the different models. For example, the ``minimal'' implementation of SU(6)/Sp(6) is bounded by f>3.0 TeV throughout most of the parameter space, and SU(4)^4/SU(3)^4 is bounded by f^2 = f_1^2+f_2^2 > (4.2 TeV)^2. In certain models, such as SU(4)^4/SU(3)^4, a large f does not directly imply a large amount of fine tuning since the heavy fermion masses that contribute to the Higgs mass can be lowered below f for a carefully chosen set of parameters. We also find that for certain models (or variations) there exist regions of parameter space in which the bound on f can be lowered into the range 1-2 TeV. These regions are typically characterized by a small mixing between heavy and standard model gauge bosons, and a small (or vanishing) coupling between heavy U(1) gauge bosons and the light fermions. Whether such a region of parameter space is natural or not is ultimately contingent on the UV completion.Comment: 32 pages, 13 figures; revised discussion of SU(4)^4/SU(3)^4 model, bound on f is slightly highe