Transonic Aerodynamic Characteristics of Two Wedge Airfoil Sections Including Unsteady Flow Studies

A two-dimensional wind-tunnel investigation has been conducted on a 20-percent-thick single-wedge airfoil section. Steady-state forces and moments were determined from pressure measurements at Mach numbers from 0.70 to about 1.25. Additional information on the flows about the single wedge is provided by means of instantaneous pressure measurements at Mach numbers up to unity. Pressure distributions were also obtained on a symmetrical double-wedge or diamond-shaped profile which had the same leading-edge included angle as the single-wedge airfoil. A comparison of the data on the two profiles to provide information on the effects of the afterbody showed that with the exception of drag, the single-wedge profile proved to be aerodynamically superior to the diamond profile in all respects. The lift effectiveness of the single-wedge airfoil section far exceeded that of conventional thin airfoil sections over the speed range of the investigation. Pitching-moment irregularities, caused by negative loadings near the trailing edge, generally associated with conventional airfoils of equivalent thicknesses were not exhibited by the single-wedge profile. Moderately high pulsating pressures existing over the base of the single-wedge airfoil section were significantly reduced as the Mach number was increased beyond 0.92 and the boundaries of the dead airspace at the base of the model converged to eliminate the vortex street in the wake. Increasing the leading-edge radius from 0 to 1 percent of the chord had a minor effect on the steady-state forces and generally raised the level of pressure pulsations over the forward part of the single-wedge profile

Effect of Rivet Rows on Propagation of Lambn Waves in Mechanically Fastened Two-Layer Aluminum Plates

Feasibility of using Lamb waves for disbonds and corrosion detections in aircraft fuselage structures was investigated in recent years. Measurement performed on various laboratory-fabricated specimens as well as on panels removed from aircrafts has shown consistent results and demonstrated its potential applications for large area structural integrity evaluation [1–3]. It has been observed that structural flaws existing on the path of Lamb waves not only changed amplitude of waves but also affected their velocities as well. Amplitude change caused by a disbond of size less than 0.5 in. × 0.5 in. was significant and has been measured. Variation in phase velocity was used to quantify the corrosion-induced thickness reduction in aluminum sheets. An area of size 1 in. × 1 in. with 8% thickness loss in subsurface of an 1 mm thick aluminum plate was detected by monitoring the phase velocity increase of SO mode. While these tests made major progresses toward developing a practical and low cost flaw assessment system, effects due to the presence of certain structural elements, such as coatings and fasteners, on the propagation of Lamb waves are becoming important issues, and need to be analyzed. These effects are themselves interesting physical phenomenon and worth investigation, however, it is hoped that propagation variations of waves induced by structural defects can be separated from these effects and be quantitatively correlated to the physical properties of defects

Mach 6 experimental and theoretical stability and performance of a cruciform missile at angles of attack up to 65 degrees

An experimental and theoretical investigation of the longitudinal and lateral-directional stability and control of an axisymmetric cruciform-finned missile has been conducted at Mach 6. The angle-of-attack range extended from 20 to 65 deg to encompass maximum lift. Longitudinal stability, performance, and trim could be accurately predicted with the fins at a fin roll angle of 0 deg but not when the fins were at a fin roll angle of 45 deg. At this roll angle, windward fin choking occurred at angles of attack above 50 deg and reduced the effectiveness of the fins and caused pitch-up

Do Higher Cigarette Prices Encourage Youth to Use Marijuana?

Every major national tobacco legislation proposed in the past two years has called for significant increases in the price of cigarettes as a way to discourage youths from smoking. One argument used to oppose these bills is that increases in the price of cigarettes would cause youths to substitute marijuana for cigarettes. Although it has long been believed that cigarettes are a gateway drug,' no economic research has been done to determine whether cigarettes and marijuana are economic complements or substitutes. This paper begins to fill the void in the current research by examining the contemporaneous relationship between the demands for cigarettes and marijuana among a nationally representative sample of 8th, 10th and 12th graders from the 1992-1994 Monitoring the Future Project. Two part models are used to estimate reduced form demand equations. Examination of the cross-price effects clearly shows that higher cigarette prices will not increase marijuana use among youths. In addition to reducing youth smoking, we find that higher cigarette prices significantly reduce the average level of marijuana used by current users. Cigarette prices also have a negative effect on the probability of using marijuana findings are not significant at conventional levels.

Cognitive representations of disability behaviours in people with mobility limitations : consistency with theoretical constructs

Disability is conceptualised as behaviour by psychological theory and as a result of bodily impairment by medical models. However, how people with disabilities conceptualise those disabilities is unclear. The purpose of this study was to examine disability representations in people with mobility disabilities. Thirteen people with mobility disabilities completed personal repertory grids (using the method of triads) applied to activities used to measure disabilities. Ten judges with expertise in health psychology then examined the correspondence between the elicited disability constructs and psychological and medical models of disability. Participants with mobility disabilities generated 73 personal constructs ofdisability. These constructs were judged consistent with the content of two psychological models, namely the theory of planned behaviour and social cognitive theory and with the main medical model of disability, the International Classification of Functioning Disability and Health.Individuals with activity limitations conceptualise activities in a manner that is compatible with both psychological and medical models. This ensures adequate communication in contexts where the medical model is relevant, e.g. clinical contexts, as well as in everyday conversation about activities and behaviours. Finally, integrated models of disability may be of value for theory driven interdisciplinary approaches to disability and rehabilitation

Transcriptomic analysis of autistic brain reveals convergent molecular pathology.

Autism spectrum disorder (ASD) is a common, highly heritable neurodevelopmental condition characterized by marked genetic heterogeneity. Thus, a fundamental question is whether autism represents an aetiologically heterogeneous disorder in which the myriad genetic or environmental risk factors perturb common underlying molecular pathways in the brain. Here, we demonstrate consistent differences in transcriptome organization between autistic and normal brain by gene co-expression network analysis. Remarkably, regional patterns of gene expression that typically distinguish frontal and temporal cortex are significantly attenuated in the ASD brain, suggesting abnormalities in cortical patterning. We further identify discrete modules of co-expressed genes associated with autism: a neuronal module enriched for known autism susceptibility genes, including the neuronal specific splicing factor A2BP1 (also known as FOX1), and a module enriched for immune genes and glial markers. Using high-throughput RNA sequencing we demonstrate dysregulated splicing of A2BP1-dependent alternative exons in the ASD brain. Moreover, using a published autism genome-wide association study (GWAS) data set, we show that the neuronal module is enriched for genetically associated variants, providing independent support for the causal involvement of these genes in autism. In contrast, the immune-glial module showed no enrichment for autism GWAS signals, indicating a non-genetic aetiology for this process. Collectively, our results provide strong evidence for convergent molecular abnormalities in ASD, and implicate transcriptional and splicing dysregulation as underlying mechanisms of neuronal dysfunction in this disorder