WL 17: A Young Embedded Transition Disk

We present the highest spatial resolution ALMA observations to date of the Class I protostar WL 17 in the $\rho$ Ophiuchus L1688 molecular cloud complex, which show that it has a 12 AU hole in the center of its disk. We consider whether WL 17 is actually a Class II disk being extincted by foreground material, but find that such models do not provide a good fit to the broadband SED and also require such high extinction that it would presumably arise from dense material close to the source such as a remnant envelope. Self-consistent models of a disk embedded in a rotating collapsing envelope can nicely reproduce both the ALMA 3 mm observations and the broadband SED of WL 17. This suggests that WL 17 is a disk in the early stages of its formation, and yet even at this young age the inner disk has been depleted. Although there are multiple pathways for such a hole to be created in a disk, if this hole were produced by the formation of planets it could place constraints on the timescale for the growth of planetesimals in protoplanetary disks.Comment: 7 pages, 3 figures, 2 tables, accepted for publication in ApJ

A VLA Survey For Faint Compact Radio Sources in the Orion Nebula Cluster

We present Karl G. Janksy Very Large Array (VLA) 1.3 cm, 3.6 cm, and 6 cm continuum maps of compact radio sources in the Orion Nebular Cluster. We mosaicked 34 square arcminutes at 1.3 cm, 70 square arcminutes at 3.6 cm and 109 square arcminutes at 6 cm, containing 778 near-infrared detected YSOs and 190 HST-identified proplyds (with significant overlap between those characterizations). We detected radio emission from 175 compact radio sources in the ONC, including 26 sources that were detected for the first time at these wavelengths. For each detected source we fit a simple free-free and dust emission model to characterize the radio emission. We extrapolate the free-free emission spectrum model for each source to ALMA bands to illustrate how these measurements could be used to correctly measure protoplanetary disk dust masses from sub-millimeter flux measurements. Finally, we compare the fluxes measured in this survey with previously measured fluxes for our targets, as well as four separate epochs of 1.3 cm data, to search for and quantify variability of our sources.Comment: 13 pages, 6 figures, 4 tables, ApJ, in pres

High-precision Dynamical Masses of Pre-main-sequence Stars with ALMA and Gaia

The Keplerian rotation in protoplanetary disks can be used to robustly measure stellar masses at very high precision if the source distance is known. We present Atacama Large Millimeter/submillimeter Array (ALMA) observations of spatially and spectrally resolved (CO)-C-12 (2-1) emission toward the disks around 2MASS J16262774-2527247 (the tertiary companion to ROXs 12 at 5100 au), CT Cha, and DH Tau. We employ detailed modeling of the Keplerian rotation profile, coupled with accurate distances from Gaia, to directly measure the stellar masses with similar to 2% precision. We also compare these direct mass measurements with the masses inferred from evolutionary models, determined in a statistically rigorous way. We find that 2MASS J16262774-2527247 has a mass of 0.535(-)(0.007)(+0.006) M-circle dot and CT Cha has a mass of 0.796(-0.014)(+0.015) M-circle dot, broadly consistent with evolutionary models, although potentially significant differences remain. DH Tau has a mass of 0.101(-0.003)(+0.004) M-circle dot, but it suffers from strong foreground absorption that may affect our mass estimate. The combination of ALMA, Gaia, and codes like pdspy, presented here, can be used to infer the dynamical masses for large samples of young stars and substellar objects, and place constraints on evolutionary models.Heising-Simons Foundation; Homer L. Dodge Endowed Chair; National Science Foundation Graduate Research Fellowship [2012115762]; NSF AAG grant [1311910]; NASA's Science Mission DirectorateThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]

Serotonergic Contributions to Human Brain Aggression Networks

Aggressive behavior is associated with dysfunctional frontolimbic emotion regulation circuits. Recent findings suggest serotonin as a primary transmitter for prefrontal amygdala control. However, the association between serotonin levels, amygdala regulation, and aggression is still a matter of debate. Neurobehavioral models furthermore suggest a possible mediating influence of the monoamine oxidase A gene (MAOA) on this brain-behavior relationship, with carriers of low expressing allele varieties being a risk group for aggression. In the present study, we investigated the influence of brain serotonin modulation and MAOA genotype on functional amygdala connectivity during aggressive behavior. Modulation of serotonergic neurotransmission with acute tryptophan depletion (ATD) and placebo were administered in a double-blind, cross-over design in 38 healthy male participants. Aggressive behavior was modeled in a violent video game during simultaneous assessment of brain activation with functional magnetic resonance imaging (fMRI). Trait aggression was measured with the Buss-Perry Aggression Questionnaire (BP-AQ), and MAOA genotypes were assessed from blood samples. Voxel-wise functional connectivity with anatomically defined amygdala was calculated from the functional data. Tryptophan depletion with ATD reduced aggression-specific amygdala connectivity with bilateral supramarginal gyrus. Moreover, ATD impact was associated with trait aggression and MAOA genotype in prefrontal cortex regions. In summary, serotonergic corticolimbic projections contribute to aggressive behavior. Genotype-specific vulnerability of frontolimbic projections may underlie the elevated risk in low expressing allele carriers

ALMA Discovery of a Disk around the Planetary-Mass Companion Sr 12 C

We report an Atacama Large Millimeter/submillimeter Array 0.88 mm (Band 7) continuum detection of the accretion disk around SR 12 c, an ∼11 M Jup planetary-mass companion (PMC) orbiting its host binary at 980 au. This is the first submillimeter detection of a circumplanetary disk around a wide PMC. The disk has a flux density of 127 ± 14 μJy and is not resolved by the ∼0.″1 beam, so the dust disk radius is likely less than 5 au and can be much smaller if the dust continuum is optically thick. If, however, the dust emission is optically thin, then the SR 12 c disk has a comparable dust mass to the circumplanetary disk around PDS 70 c but is about five times lower than that of the ∼12 M Jup free-floating OTS 44. This suggests that disks around bound and unbound planetary-mass objects can span a wide range of masses. The gas mass estimated with an accretion rate of 10-11 M ⊙ yr-1 implies a gas-to-dust ratio higher than 100. If cloud absorption is not significant, a nondetection of 12CO(3-2) implies a compact gas disk around SR 12 c. Future sensitive observations may detect more PMC disks at 0.88 mm flux densities of ≲ 100 μJy

Electrochemistry at nanoscale electrodes : individual single-walled carbon nanotubes (SWNTs) and SWNT-templated metal nanowires

Individual nanowires (NWs) and native single-walled carbon nanotubes (SWNTs) can be readily used as well-defined nanoscale electrodes (NSEs) for voltammetric analysis. Here, the simple photolithography-free fabrication of submillimeter long Au, Pt, and Pd NWs, with sub-100 nm heights, by templated electrodeposition onto ultralong flow-aligned SWNTs is demonstrated. Both individual Au NWs and SWNTs are employed as NSEs for electron-transfer (ET) kinetic quantification, using cyclic voltammetry (CV), in conjunction with a microcapillary-based electrochemical method. A small capillary with internal diameter in the range 30–70 μm, filled with solution containing a redox-active mediator (FcTMA+ ((trimethylammonium)methylferrocene), Fe(CN)64–, or hydrazine) is positioned above the NSE, so that the solution meniscus completes an electrochemical cell. A 3D finite-element model, faithfully reproducing the experimental geometry, is used to both analyze the experimental CVs and derive the rate of heterogeneous ET, using Butler–Volmer kinetics. For a 70 nm height Au NW, intrinsic rate constants, k0, up to ca. 1 cm s–1 can be resolved. Using the same experimental configuration the electrochemistry of individual SWNTs can also be accessed. For FcTMA+/2+ electrolysis the simulated ET kinetic parameters yield very fast ET kinetics (k0 > 2 ± 1 cm s–1). Some deviation between the experimental voltammetry and the idealized model is noted, suggesting that double-layer effects may influence ET at the nanoscale

Reinventing grounded theory: some questions about theory, ground and discovery

Grounded theory’s popularity persists after three decades of broad-ranging critique. In this article three problematic notions are discussed—‘theory,’ ‘ground’ and ‘discovery’—which linger in the continuing use and development of grounded theory procedures. It is argued that far from providing the epistemic security promised by grounded theory, these notions—embodied in continuing reinventions of grounded theory—constrain and distort qualitative inquiry, and that what is contrived is not in fact theory in any meaningful sense, that ‘ground’ is a misnomer when talking about interpretation and that what ultimately materializes following grounded theory procedures is less like discovery and more akin to invention. The procedures admittedly provide signposts for qualitative inquirers, but educational researchers should be wary, for the significance of interpretation, narrative and reflection can be undermined in the procedures of grounded theory

Diabetic Kidney Disease in FVB/NJ Akita Mice: Temporal Pattern of Kidney Injury and Urinary Nephrin Excretion

Akita mice are a genetic model of type 1 diabetes. In the present studies, we investigated the phenotype of Akita mice on the FVB/NJ background and examined urinary nephrin excretion as a marker of kidney injury. Male Akita mice were compared with non-diabetic controls for functional and structural characteristics of renal and cardiac disease. Podocyte number and apoptosis as well as urinary nephrin excretion were determined in both groups. Male FVB/NJ Akita mice developed sustained hyperglycemia and albuminuria by 4 and 8 weeks of age, respectively. These abnormalities were accompanied by a significant increase in systolic blood pressure in 10-week old Akita mice, which was associated with functional, structural and molecular characteristics of cardiac hypertrophy. By 20 weeks of age, Akita mice developed a 10-fold increase in albuminuria, renal and glomerular hypertrophy and a decrease in the number of podocytes. Mild-to-moderate glomerular mesangial expansion was observed in Akita mice at 30 weeks of age. In 4-week old Akita mice, the onset of hyperglycemia was accompanied by increased podocyte apoptosis and enhanced excretion of nephrin in urine before the development of albuminuria. Urinary nephrin excretion was also significantly increased in albuminuric Akita mice at 16 and 20 weeks of age and correlated with the albumin excretion rate. These data suggest that: 1. FVB/NJ Akita mice have phenotypic characteristics that may be useful for studying the mechanisms of kidney and cardiac injury in diabetes, and 2. Enhanced urinary nephrin excretion is associated with kidney injury in FVB/NJ Akita mice and is detectable early in the disease process