5,101 research outputs found

    A model composite assessment of the enhancement of Arctic warming by sea ice retreat

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    Thesis (M.S.) University of Alaska Fairbanks, 2006Five global climate models used in the Arctic Climate Impact Assessment are utilized to estimate the local enhancement of Arctic warming attributable to sea ice retreat in 21st century B2-scenario greenhouse gas (GHG) simulations. The models show a wide range of ice retreat, resulting in a corresponding range in the enhancement of warming. The enhancement is highly seasonal, varying locally from essentially zero in the summer to several degrees CC) in the late autumn and early winter. The composite climate model response to GHG forcing manifests as a nonlinear amplification of seasonally modulated warming enhancement. The magnitude of the warming enhancement increases with the threshold decline in ice concentration used to define retreat because higher thresholds better isolate the warming enhancement signal over ice retreat areas. A threshold of 20% ensures that all models in this study have enough ice retreat area to sample the enhancement because all start with ice concentrations at least that high over substantial northern hemisphere areas. All estimates are lower bounds because they do not account for advective effects

    Risk stratification in non-ST elevation acute coronary syndromes: risk scores, biomarkers and clinical judgment

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    Undifferentiated chest pain is one of the most common reasons for emergency department attendance and admission to hospitals. Non-ST elevation acute coronary syndrome (NSTE-ACS) is an important cause of chest pain, and accurate diagnosis and risk stratification in the emergency department must be a clinical priority. In the future, the incidence of NSTE-ACS will rise further as higher sensitivity troponin assays are implemented in clinical practice. In this article, we review contemporary approaches for the diagnosis and risk stratification of NSTE-ACS during emergency care. We consider the limitations of current practices and potential improvements. Clinical guidelines recommend an early invasive strategy in higher risk NSTE-ACS. The Global Registry of Acute Coronary Events (GRACE) risk score is a validated risk stratification tool which has incremental prognostic value for risk stratification compared with clinical assessment or troponin testing alone. In emergency medicine, there has been a limited adoption of the GRACE score in some countries (e.g. United Kingdom), in part related to a delay in obtaining timely blood biochemistry results. Age makes an exponential contribution to the GRACE score, and on an individual patient basis, the risk of younger patients with a flow-limiting culprit coronary artery lesion may be underestimated. The future incorporation of novel cardiac biomarkers into this diagnostic pathway may allow for earlier treatment stratification. The cost-effectiveness of the new diagnostic pathways based on high-sensitivity troponin and copeptin must also be established. Finally, diagnostic tests and risk scores may optimize patient care but they cannot replace patient-focused good clinical judgment

    Continental Shift? An Analysis of Convergence Trends in European Real Estate Equities

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    This paper investigates the effects of European monetary integration on the behavior of stock returns in European real estate companies from the perspective of a dollar-denominated investor. A range of statistical tests is applied to assess changes in segmentation, co-movement and causality. The results suggest that, relative to the wider equity markets, the dispersion of performance is higher, correlations are lower, a common contemporaneous factor has much lower explanatory power whilst lead-lag relationships are stronger. Less and slower integration is attributed to the relatively small size of the real estate securities market and the local nature of many real estate companiesā€™ portfolios.

    Monetary Integration and Real Estate Markets: An Investigation of the Impact of the Introduction of a Single Currency on Real Estate Performance

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    This paper assesses the impact of the monetary integration on different types of stock returns in Europe. In order to isolate European factors, the impact of global equity integration and small cap factors are investigated. European countries are sub-divided according to the process of monetary convergence. Analysis shows that national equity indices are strongly influenced by global market movements, with a European stock factor providing additional explanatory power. The global and European factors explain small cap and real estate stocks much less well ā€“suggesting an increased importance of ā€˜localā€™ drivers. For real estate, there are notable differences between core and non-core countries. Core European countries exhibit convergence ā€“ a convergence to a European rather than a global factor. The non-core countries do not seem to exhibit common trends or movements. For the non-core countries, monetary integration has been associated with increased dispersion of returns, lower correlation and lower explanatory power of a European factor. It is concluded that this may be explained by divergence in underlying macro-economic drivers between core and non-core countries in the post-Euro period.

    Debugging the Tallinn Manual 2.0\u27s Application of the Due Diligence Principle to Cyber Operations

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    As global cyber connectivity increases, so does opportunities for large-scale nefarious cyber operations. These novel circumstances have necessitated the application of old-world customs to an increasingly complex world. To meet this challenge, the Tallinn Manual 2.0 on the International Law Applicable to Cyber Operations was created. The Manual provides 154 black letter rules detailing how international law applies to cyber operations during peacetime. Of particular import is the Manualā€™s interpretation of the due diligence principle. This principle, which defines the contours of a stateā€™s obligation to prevent their territory to inflict extraterritorial harm, is increasingly significant in light of the above-mentioned increase in global network connectivity. It is with regards to this principal where the Manualā€™s application is flawed. However, because of the principleā€™s inherent flexibility, and the unique nature of the cyber risks, there are patches that are consistent with international law and would better serve global peace and security
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