Additional Siphonaptera Records From Small Mammals in the Central Upper Peninsula of Michigan

Fleas were collected from mammals during the period 1990-1992 in two upper peninsula counties. Identified specimens were compared to existing distribution records for both parasite and host. Only those records which are newly documented for county, upper peninsula or Michigan are listed. We report one previously unknown flea species and five new host records for Michigan. One host record is new for the upper peninsula. In addition, seven new host/parasite combinations are recorded for two central upper peninsula counties

Learning probability spaces for classification and recognition of patterns with or without supervision

Learning probability spaces for classification and recognition of patterns with or without supervisio

Establishing links between organizational climate, employee well-being and historical patient outcomes

This research undertaken in collaboration with Queensland Health analysed the links between dimensions of workplace climate/employee well-being contained in a number of Queensland Health databases, including the Patient Satisfaction Survey, the Clinical Incident database, the compliments and complaints database, the Variable Life Adjusted Display (VLAD) Database and the Better Workplaces Staff Opinion Survey database. Queensland Health sought to identify in what ways workplace climate is related to patient outcomes using existing datasets collected within the Queensland Health Centre for Healthcare Improvement. The process of establishing links involved matching aggregated data for specific facilities (where possible), or failing that, larger facilities (e.g. Hospital), or the Health Service District. Once the datasets had been matched on location or facility, correlations were calculated between the aggregated scores. The results demonstrated links between the data sets. These links showed that a better workplace climate is associated with greater reported numbers of clinical incidents, especially “no harm” clinical incidents. There was also a link between workplace climate and patient compliments/complaints which show that unsolicited compliments received from patients and their families are clearly related to a number of positive aspects of workplace climate (workplace morale, role clarity, and appraisal and recognition) and individual morale. The results linking workplace climate and patient satisfaction showed that there is a strong positive relationship between overall patient satisfaction and role clarity, and a negative relationship between overall patient satisfaction and both workplace distress and excessive work demands. While these results relate to historical data and therefore should not be construed to reflect the current state of operation within Queensland Health, they are still indicative of some very important relationships. This is the first study to demonstrate that more positive clinical management practices, better perceptions of the workplace climate and better employee well-being are a reflection of a better incident reporting and learning culture in a health care organization, ultimately resulting in improved patient outcomes

Siphonaptera Records and Host Associations From the Central and Eastern Upper Peninsula of Michigan

Fleas were collected from birds and mammals over a five year period in four upper peninsula counties. Identified specimens were compared to published records of distribution for the parasite species and its host species, and only those records which are new county distributions for host or parasite are listed. Four new host records for Michigan, four new flea distribution records for the upper peninsula, and 26 new county records are listed

A Comparative Study of the Magnitude, Frequency and Distribution of Intense Rainfall in the United Kingdom

During the 1960s, a study was made of the magnitude, frequency and distribution of intense rainfall over the UK, employing data from more than 120 daily-read rain gauges covering the period 1911 to 1960. Using the same methodology, that study was recently updated utilizing data for the period 1961 to 2006 for the same gauges, or from those nearby. This paper describes the techniques applied to ensure consistency of data and statistical modelling. It presents a comparison of patterns of extreme rainfalls for the two periods and discusses the changes that have taken place. Most noticeably, increases up to 20% have occurred in the north west of the country and in parts of East Anglia. There have also been changes in other areas, including decreases of the same magnitude over central England. The implications of these changes are considered

Modeling quasar accretion disc temperature profiles

Microlensing observations indicate that quasar accretion discs have half-light radii larger than expected from standard theoretical predictions based on quasar fluxes or black hole masses. Blackburne and colleagues have also found a very weak wavelength dependence of these half-light radii. We consider disc temperature profile models that might match these observations. Nixon and colleagues have suggested that misaligned accretion discs around spinning black holes will be disrupted at radii small enough for the Lense-Thirring torque to overcome the disc's viscous torque. Gas in precessing annuli torn off a disc will spread radially and intersect with the remaining disc, heating the disc at potentially large radii. However, if the intersection occurs at an angle of more than a degree or so, highly supersonic collisions will shock-heat the gas to a Compton temperature of T~10^7 K, and the spectral energy distributions (SEDs) of discs with such shock-heated regions are poor fits to observations of quasar SEDs. Torn discs where heating occurs in intermittent weak shocks that occur whenever the intersection angle reaches a tenth of a degree pose less of a conflict with observations, but do not have significantly larger half-light radii than standard discs. We also study two phenomenological disc temperature profile models. We find that discs with a temperature spike at relatively large radii and lowered temperatures at radii inside the spike yield improved and acceptable fits to microlensing sizes in most cases. Such temperature profiles could in principle occur in sub-Keplerian discs partially supported by magnetic pressure. However, such discs overpredict the fluxes from quasars studied with microlensing except in the limit of negligible continuum emission from radii inside the temperature spike.Comment: Submitted to MNRAS. Comments welcome. 20 pages, 5 figure

Murine terminal deoxynucleotidyl transferase: cellular distribution and response to cortisone

The mouse thymus contains two forms of terminal deoxynucleotidyl transferase (TdT) which are distinguishable by the salt concentration necessary to elute them from a phosphocellulose column, by their distrubtion among the thymocyte subpopulations, and by their sensitivity to cortisone treatment. In the whole thymus the later eluting peak (peak II) is the predominant one with about 3-10% of the total activity appearing in peak I. Both peak I and peak II activities are most sensitively assayed by the polymerization of dGMP onto an oligo(dA) primer. The minor population of thymocytes which is less dense and cortisone-resistant contains a higher specific activity of peak I TdT. The majority of TdT activity is, however, found in the major population of thymocytes which occurs in the center region of a bovine serum albumin gradient and is cortisone-sensitive. A very low level of an activity indistinguishable from peak II TdT activity is also detected in the mouse bone marrow. Other tissues, such as spleen, liver, heart, and brain lack detectable amounts of TdT activity

Weak-Field Thermal Hall Conductivity in the Mixed State of d-Wave Superconductors

Thermal transport in the mixed state of a d-wave superconductor is considered within the weak-field regime. We express the thermal conductivity, $\kappa_{xx}$, and the thermal Hall conductivity, $\kappa_{xy}$, in terms of the cross section for quasiparticle scattering from a single vortex. Solving for the cross section (neglecting the Berry phase contribution and the anisotropy of the gap nodes), we obtain $\kappa_{xx}(H,T)$ and $\kappa_{xy}(H,T)$ in surprisingly good agreement with the qualitative features of the experimental results for YBa$_{2}$Cu$_{3}$O$_{6.99}$. In particular, we show that the simple, yet previously unexpected, weak-field behavior, $\kappa_{xy}(H,T) \sim T\sqrt{H}$, is that of thermally-excited nodal quasiparticles, scattering primarily from impurities, with a small skew component provided by vortex scattering.Comment: 5 pages, 2 figures; final version as published in Phys Rev Let

Study of meta-analysis strategies for network inference using information-theoretic approaches

© 2017 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.Reverse engineering of gene regulatory networks (GRNs) from gene expression data is a classical challenge in systems biology. Thanks to high-throughput technologies, a massive amount of gene-expression data has been accumulated in the public repositories. Modelling GRNs from multiple experiments (also called integrative analysis) has; therefore, naturally become a standard procedure in modern computational biology. Indeed, such analysis is usually more robust than the traditional approaches focused on individual datasets, which typically suffer from some experimental bias and a small number of samples. To date, there are mainly two strategies for the problem of interest: the first one (”data merging”) merges all datasets together and then infers a GRN whereas the other (”networks ensemble”) infers GRNs from every dataset separately and then aggregates them using some ensemble rules (such as ranksum or weightsum). Unfortunately, a thorough comparison of these two approaches is lacking. In this paper, we evaluate the performances of various metaanalysis approaches mentioned above with a systematic set of experiments based on in silico benchmarks. Furthermore, we present a new meta-analysis approach for inferring GRNs from multiple studies. Our proposed approach, adapted to methods based on pairwise measures such as correlation or mutual information, consists of two steps: aggregating matrices of the pairwise measures from every dataset followed by extracting the network from the meta-matrix.Peer ReviewedPostprint (author's final draft