Neuropsychiatric features of children with systemic somatovegetative disorders (by the example of atopic dermatitis, bronchial asthma and gastroesophageal reflux disease)

Objective: to study the clinical neuropsychiatric and neuropsychological features of children suffering from systemic somatovegetative disorders.Materials and methods: the study involved children from 5 to 12 years old with an established diagnosis of bronchial asthma — 108 children; atopic dermatitis — 105 children; gastroesophageal reflux disease — 112 children; the control group consisted of 60 same age healthy children. All children underwent clinical-anamnestic, neurological, psychopathological and neuropsychological research.Results: the children with systemic somatovegetative disorders have a significantly high incidence of pathogenic factors of central nervous system damage in early stages of ontogenesis (pathology of pregnancy and childbirth). Early sensory and motor deprivation due to somatic suffering aggravates neuropsychiatric deficiency. Neuropsychological disorders were predominantly represented by a violation of the perception of their body, lack of kinesthetic and motor functions, spatial and quasi-spatial representations.Conclusion: the clinical dynamics of neuropsychiatric disorders in children with systemic somatovegetative disorders corresponds to the dynamics of residual cerebral organic impairment with a stage-age changes of syndromes. The revealed neuropsychological disorders correspond to preferential damage to the first (energy) functional block of the brain

Influence of the order parameter on the anchoring energy of liquid crystals

No theory of the polar and azimuthal anchoring energies of liquid crystals (LCs) has been developed on a molecular level, despite the scientific and practical topicality of the problem. The interaction energies of mesogenic molecules with graphite and polyethylene surfaces calculated previously by the method of atom-atom potentials are in good agreement with the experimental data, but, at the same time, the calculated polar and azimuthal anchoring energies are larger than their experimental values by one and two orders of magnitude, respectively. To explain these values, the anchoring energy has been assumed to depend not only on the interaction with the surface but also on the interaction between the LC molecules arranged in the model in the form of quasi-layers. The mesogenic molecules have been modeled by rods with virtual C' atoms (carbon atoms with hydrogen atoms attached to them) "threaded" on them. The molecule orientation has been specified by the polar and azimuthal angles theta (i) , phi (i) and theta (j) , phi (j) relative to the directors of the ith and jth layers. The derived polar and azimuthal anchoring energies as well as their dependences on the order parameter have turned out to be close to the experimental data

Anchoring Energy of Liquid Crystals

The liquid crystals anchoring theory is considered on the molecular level. Earlier calculations of mesogenic molecules interaction energy with graphite and PE surface give results being one-two orders higher than experimentally obtained values. To explain the experimental values of anchoring energy we proposed its dependence on the interaction between liquid crystal layers. In our calculations we have simulated the mesogen molecules by virtual rod-like molecules. The molecules orientation was given by polar and azimuthal angles towards the directors of neighboring liquid crystal layers. Obtained values of polar and azimuthal anchoring energy as well as their dependences on the order parameter are in good agreement with experimental data

Polar and azimuthal anchoring energy of liquid crystals

The interaction energy between mesogenic molecules (diphenyl, pentylbiphenyl and 4-n-octyl-4′-cyanebiphanyl) and the graphite and PE surface has been calculated using atom-atom potentials method. Polar and azimuthal anchoring energies are obtained and their dependences on the order parameter were derived. The good coincidence of calculated values of anchoring energies as well as of their dependences on the order parameter with experimental data is shown