Effective wound healing agents based on N-alkenylimidazole zinc complexes derivatives: future prospects and opportunities

The aim of the study: to provide experimental evidence for effects of recently developed zinc complexes with N-alkenylimidazole as wound healing agent

EARLY AND LATE POSTOPERATIVE COMPLICATIONS IN PATIENTS WITH LOCALIZED AND LOCALLY ADVANCED RENAL CELL CARCINOMA

BACKGROUND: Modern Russian statistics show that the percentage of renal cell carcinoma (RCC) among all oncological diseases has increased and amounted to almost 5% in 2019. The main method of treating RCC is radical nephrectomy in localized RCC, which is supplemented by the removal of regional lymph nodes in locally advanced RCC. AIM: To evaluate early and late postoperative complications in patients with localized and locally advanced renal cell carcinoma. METHODS: We've analyzed the results of surgical treatment and postoperative complications in 378 patients with clinically proven localized and locally developed RCC. RESULTS: The total number of complications after surgical treatment of patients with localized and locally advanced RCC was 24 (6.3%) patients. Moreover, in the treatment of the localized form of RCC, postoperative complications are 3 times less common than in the locally advanced form of RCC (p <0.05). The most common complication after surgical treatment of RCC was bleeding which we observed in 11(2.9%) patients. CONCLUSION: After surgical treatment of RCC, the proportion of complications is not high, but they can have unpleasant consequences. In the late postoperative period the most common complication bleeding is followed by lymphorrhea and urinary tract infections