ANTIMICROBIAL MODULATOR OF INFLAMMATORY RESPONSE IN THIRD MOLAR SURGERY COMPARED WITH CONVENTIONAL MEDICATION

Surgeries performed in retained third molars occur in the contaminated field, bringing post-operativeproblems such as pain, bleeding, discomfort, swelling, infection, trismus, and inactive days. This studyevaluated the differences between conventional medication and topical doxycycline in third molar surgery.Twenty-eight patients were selected requiring removal of four third molar. Half of the mouth was randomlyselected to undergo surgery with the use of conventional medication (analgesic, anti-inflammatory andantimicrobial) and after 25-30 days, the other half of the mouth was subjected to surgery using doxycyclinedelivered through gel nanotubes. The results showed that in both treatments there was no clinical infection.The other evaluations were significantly lower in relation to pain, bleeding, edema, inactive days, trismus, anddiscomfort when compared with conventional therapy