A Lightweight Authentication Scheme for Transport System Farecards

Proximity Integrated Circuit Cards (PICC) are widely used for public transport fare collection. The stored contents in the card can only be accessed or modified after the card is able to authenticate the Proximity Coupling Device (PCD) or reader using a shared secret key. We propose a new authentication scheme that is not based on shared secret keys. Instead, authentication is based on the card and reader being able to compute an identical pairwise key using their own private keying material obtained from the same source. The computation is done off-line and does not require the participation of a third party. It uses simple modular arithmetic operations over a small binary extension field, achieving fast computation speed using the limited resources in cards. In addition, should the keys be stolen from the cards or readers, the security of the other parts of the system cannot be compromised

Geographical differences on the mortality impact of heat waves in Europe

Climate change is potentially the biggest global health threat in the 21st century. Deaths related with heat waves and spread of infectious diseases will be part of the menace though the major impact will be caused by malnutrition, diarrhea and extreme climate events. Consequently, loss of healthy life years as a result of global climate change is predicted to be 500 times greater in poor African populations than in European populations. However, the increase of more than 2°C of average temperature will result in a negative health impact in all regions, the potential benefits of a warmer temperature being negatively compensated, heat waves being one of the largest climate change threats in the developed world

Influence of climatic variables on crown condition in pine forests of Northern Spain

Producción CientíficaThe aim of this study was to find relationships between crown condition and some climatic parameters to identify which are those having a main influence on crown condition, and how this influence is shown in the tree (crown transparency), and to contribute to the understanding of how these parameters will affect under future climate change scenarios

The biomechanics of amnion rupture: an X-ray diffraction study

Pre-term birth is the leading cause of perinatal and neonatal mortality, 40% of which are attributed to the pre-term premature rupture of amnion. Rupture of amnion is thought to be associated with a corresponding decrease in the extracellular collagen content and/or increase in collagenase activity. However, there is very little information concerning the detailed organisation of fibrillar collagen in amnion and how this might influence rupture. Here we identify a loss of lattice like arrangement in collagen organisation from areas near to the rupture site, and present a 9% increase in fibril spacing and a 50% decrease in fibrillar organisation using quantitative measurements gained by transmission electron microscopy and the novel application of synchrotron X-ray diffraction. These data provide an accurate insight into the biomechanical process of amnion rupture and highlight X-ray diffraction as a new and powerful tool in our understanding of this process

A combinatorial TIR1/AFB–Aux/IAA co-receptor system for differential sensing of auxin

The plant hormone auxin regulates virtually every aspect of plant growth and development. Auxin acts by binding the F-box protein transport inhibitor response 1 (TIR1) and promotes the degradation of the AUXIN/INDOLE-3-ACETIC ACID (Aux/IAA) transcriptional repressors. Here we show that efficient auxin binding requires assembly of an auxin co-receptor complex consisting of TIR1 and an Aux/IAA protein. Heterologous experiments in yeast and quantitative IAA binding assays using purified proteins showed that different combinations of TIR1 and Aux/IAA proteins form co-receptor complexes with a wide range of auxin-binding affinities. Auxin affinity seems to be largely determined by the Aux/IAA. As there are 6 TIR1/AUXIN SIGNALING F-BOX proteins (AFBs) and 29 Aux/IAA proteins in Arabidopsis thaliana, combinatorial interactions may result in many co-receptors with distinct auxin-sensing properties. We also demonstrate that the AFB5–Aux/IAA co-receptor selectively binds the auxinic herbicide picloram. This co-receptor system broadens the effective concentration range of the hormone and may contribute to the complexity of auxin response

Freedom of choice to migrate: adaptation to climate change in Bangladesh

Adaptation is an essential part of climate change policy. In areas where impacts are likely to be severe, migration is considered to be an adaptation option. In Bangladesh coastal areas migration due to climate change is contingent on people’s freedom of choice at individual and household level. Following Amartya Sen’s capability approach, we argue that there should be a line drawn between migrations by free choice versus forced migration. Sen’s capability approach focuses on the importance of people’s freedom of choice to act, and the ability to achieve what they consider valuable in their life. In this paper, we use an extensive empirical work engaging 22 focus groups discussions (8–12 individuals in each group) and 14 Key Informants Interviews in South-West Bangladesh to elicit how freedom of choice changes with the economic class and social status of an individual. Using these data we apply Sen’s capability approach to understand the role of the freedom of choice when considering migration as an adaptation option. We argue that the capability approach is essential in revealing a thin border between migration as a (planned) adaptation option and forced migration

Quality of life during olaparib maintenance therapy in platinum-sensitive relapsed serous ovarian cancer

Maintenance monotherapy with the poly(ADP-ribose) polymerase inhibitor olaparib significantly prolongs progression-free survival over placebo in patients with platinum-sensitive relapsed serous ovarian cancer, with greatest benefit seen in patients with a BRCA1/2 mutation (BRCAm). Preservation of health-related quality of life (HRQoL) is important during maintenance therapy; we evaluated the effect of olaparib on HRQoL in this Phase II trial (NCT00753545, Study 19).status: publishe