2,448 research outputs found

    Development of a Chaff Dispense Program for Target Tracking Radar Deception

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    This study aims to develop an appropriate chaff dispensing program to deceive the target tracking radar (TTR) effectively. Chaff is a countermeasure commonly used by fighter aircraft to deceive TTR. However, there has been a lack of methodology for calculating chaff dispense programs that take into account the specific characteristics of the fighter, chaff, and TTR. This study proposes a methodology that considers these variables to calculate chaff dispense programs and addresses this gap. The proposed method is demonstrated through TESS engagement, which shows its effectiveness in various engagement situations

    Topological Structure of Dense Hadronic Matter

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    We present a summary of work done on dense hadronic matter, based on the Skyrme model, which provides a unified approach to high density, valid in the large NcN_c limit. In our picture, dense hadronic matter is described by the {\em classical} soliton configuration with minimum energy for the given baryon number density. By incorporating the meson fluctuations on such ground state we obtain an effective Lagrangian for meson dynamics in a dense medium. Our starting point has been the Skyrme model defined in terms of pions, thereafter we have extended and improved the model by incorporating other degrees of freedom such as dilaton, kaons and vector mesons.Comment: 13 pages, 8 figures, Talk given at the KIAS-APCTP Symposium in Astro-Hadron Physics "Compact Stars: Quest for New States of Dense Matter", November 10-14, 2003, Seoul, Korea, published by World Scientific. Based on talk by B.-Y. Par

    Hypertensive brainstem encephalopathy involving deep supratentorial regions: does only blood pressure matter?

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    We report on a 42-year-old female patient who presented with high arterial blood pressure of 245/150 mmHg and hypertensive brainstem encephalopathy that involved the brainstem and extensive supratentorial deep gray and white matter. The lesions were nearly completely resolved several days after stabilization of the arterial blood pressure. Normal diffusion-weighted imaging findings and high apparent diffusion coefficient values suggested that the main pathomechanism was vasogenic edema owing to severe hypertension. On the basis of a literature review, the absolute value of blood pressure or whether the patient can control his/her blood pressure seems not to be associated with the degree of the lesions evident on magnetic resonance imaging. It remains to be determined if the acceleration rate and the duration of elevated arterial blood pressure might play a key role in the development of the hypertensive encephalopathy pattern

    A New p53 Target Gene, RKIP, Is Essential for DNA Damage-Induced Cellular Senescence and Suppression of ERK Activation

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    Abstractp53, a strong tumor suppressor protein, is known to be involved in cellular senescence, particularly premature cellular senescence. Oncogenic stresses, such as Ras activation, can initiate p53-mediated senescence, whereas activation of the Ras-mitogen-activated protein kinase (MAPK) pathway can promote cell proliferation. These conflicting facts imply that there is a regulatory mechanism for balancing p53 and Ras-MAPK signaling. To address this, we evaluated the effects of p53 on the extracellular signal-regulated kinase (ERK) activation and found that p53 could suppress ERK activation through de novo synthesis. Through several molecular biologic analyses, we found that RKIP, an inhibitor of Raf kinase, is responsible for p53-mediated ERK suppression and senescence. Overexpression of RKIP can induce cellular senescence in several types of cell lines, including p53-deficient cells, whereas the elimination of RKIP by siRNA or forced expression of ERK blocks p53-mediated cellular senescence. These results suggested that RKIP is an essential protein for cellular senescence. Moreover, modification of the p53 serine 46 residue was critical for RKIP induction and ERK suppression as well as cellular senescence. These results indicated that RKIP is a novel p53 target gene that is responsible for p53-mediated cellular senescence and tumor suppressor protein expression

    A Surgically Treated Case of Chronic Necrotizing Aspergillosis with Pleural Invasion

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    Aspergillus is a ubiquitous fungus and can cause many levels of disease severity. Chronic necrotizing aspergillosis is a rare disease and few cases have been reported in Korea. We experienced a case of pleural aspergillosis that was treated successfully with medical and surgical interventions. The 52-year-old man who was diagnosed with chronic necrotizing pulmonary aspergillosis underwent surgical treatment including a lobectomy, decortication, and myoplasty. The patient was also medically treated with amphotericin B followed by voriconazole. Pleural irrigation with amphotericin B was also performed. A multi-dimensional approach should be considered for treating chronic necrotizing pulmonary aspergillosis

    Effect of Varying the Semiconducting/Metallic Tube Ratio on the Performance of Mixed Single-Walled Carbon Nanotube Network Gas Sensors

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    The sensing properties of mixed networks consisting of semiconducting and metallic single-walled carbon nanotubes (SWCNTs) have been found to largely vary depending on the ratio of semiconducting to metallic tubes. Solution-deposited 99% semiconductor-enriched nanotube networks exhibited a sensitivity of 1.908%/ppm, whereas the unenriched 66% and 90% enriched samples exhibited a sensitivity of 0.027%/ppm and 0.113%/ppm, respectively. These results suggest that it is extremely important to minimize the metallic pathways to achieve high sensitivity. After an oxygen plasma treatment, the unenriched 66% sample exhibited a 526% increase in sensitivity (0.142%/ppm) compared to the untreated one, whereas the 90% device demonstrated a sensitivity of 1.521%/ppm, which corresponds to an improvement in the sensitivity of 13.5 times the pristine 90% sample. In addition, the plasma-treated sensors exhibited a much faster response time than the untreated one. The significant improvement in the performance of the highly enriched network sensors was explained by the large increase in the anchoring sites for ammonia molecules on the surface of the semiconducting single-walled CNTs and the faster charge transfer from absorbed molecules

    The Effectiveness of Moxibustion: An Overview During 10 Years

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    Moxibustion has been used to treat various types of disease. However, there is still insufficient evidence regarding its effectiveness. This study was performed to summarize and evaluate the effectiveness of moxibustion. A search was performed for all randomized controlled trials in PubMed between January 1998 and July 2008 with no language restriction. The results yielded 47 trials in which six moxibustion types were applied to 36 diseases ranging from breech presentation to digestive disorders. Moxibustion was compared to three types of control group: general care, Oriental medical therapies or waiting list. Moxibustion was superior to the control in 14 out of 54 control groups in 46 studies. There were no significant differences among groups in 7 studies, and the outcome direction was not determined in 33 studies. Seven studies were included in a meta-analysis. Moxibustion was more effective than medication in two ulcerative colitis studies (relative risk (95% CI), 2.20 (1.37, 3.52), P = .001, I2 = 0%). Overall, our results did not support the effectiveness of moxibustion in specific diseases due to the limited number and low quality of the studies and inadequate use of controls. In order to provide appropriate evidence regarding the effectiveness of moxibustion, more rigorous clinical trials using appropriate controls are warranted
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