Analisis Faktor-Faktor Yang Mempengaruhi Dimensi Penyusun Indeks Pembangunan Manusia (IPM) Di Provinsi Sulawesi Utara

This study aims to analyze the Pure Partisipation Rate of SD/MI and Gross Regional Domestic Product which affect the Education Dimension (Expected Years of Schooling) in North Sulawesi Province and to analyze the number of poor people and the open unemployment rate which affect the Expenditure Dimension (Decent Standard of Living) in North Sulawesi Province. This research was conducted from March to May 2023. The type of data used is secondary data from published reports produced by the North Sulawesi Central Statistics Agency for 2021. The objects in this study were 15 districts/cities in North Sulawesi province. The results of the study show that the Pure Partisipation Rate of SD/MI and Gross Regional Domestic Product simultaneously have an influence on the Old School Expectancy. The influence exerted by PPR SD/MI is 37.7% and GRDP is 25.8%. The number of poor people and the open unemployment rate simultaneously have an influence on per capita spending. The influence given by the number of poor people is 39.9% and the open unemployment rate is 45.8%

EFFECT OF MICROPLASTIC INTAKE ON INTESTINAL AND PANCREATIC CELL DAMAGE

Introduction: Microplastics are plastic particles that result from the breakdown of larger plastic particles into smaller pieces and are found in natural environments such as oceans, beaches, and land. Microplastics harm the environment and affect human health. The main entrance of microplastics into the body is the digestive system, through the food and drinks we consume daily. Various investigations have shown that human feces samples contain microplastics that come from ingestion of contaminated food. If it continues, it can damage our body cells. Objective: This research aims to demonstrate that oral administration of microplastics can impair the function of the small intestine, large intestine, and pancreas in rattus of the strain Rattus norvegicus wistar. Method: This study is a quantitative analytic investigation employing an experimental methodology on experimental animals. In this work, the experimental animals were separated into six groups, including the control group and the treatment groups X1, X2, X3, X4, and X5; microscopic observations were conducted 90 days after the microplastics were administered. Results: The comparison of the control group with each exposure group to the small intestine revealed significant results in the Pearson correlation test in groups K with X2, X3, and X4 and the Mann-Whitney difference test in groups K with X2 and X4. Comparing the control group with each exposure group to the large intestine revealed no significant results in the Pearson correlation test and the Mann-Whitney difference test. Conclusion: The correlation test results between the control group and the complete exposure groups revealed significant outcomes in the small intestinal tissue but not in the large intestine and pancreas tissue

Effect of Microplastic Intake on Intestinal ond Pancreatic Cell Damage

Introduction: Microplastics are plastic particles that result from the breakdown of larger plastic particles into smaller pieces and are found in natural environments such as oceans, beaches, and land. Microplastics harm the environment and affect human health. The main entrance of microplastics into the body is the digestive system, through the food and drinks we consume daily. Various investigations have shown that human feces samples contain microplastics that come from ingestion of contaminated food. If it continues, it can damage our body cells. Objective: This research aims to demonstrate that oral administration of microplastics can impair the function of the small intestine, large intestine, and pancreas in rattus of the strain Rattus norvegicus wistar. Method: This study is a quantitative analytic investigation employing an experimental methodology on experimental animals. In this work, the experimental animals were separated into six groups, including the control group and the treatment groups X1, X2, X3, X4, and X5; microscopic observations were conducted 90 days after the microplastics were administered. Results: The comparison of the control group with each exposure group to the small intestine revealed significant results in the Pearson correlation test in groups K with X2, X3, and X4 and the Mann-Whitney difference test in groups K with X2 and X4. Comparing the control group with each exposure group to the large intestine revealed no significant results in the Pearson correlation test and the Mann-Whitney difference test. Conclusion: The correlation test results between the control group and the complete exposure groups revealed significant outcomes in the small intestinal tissue but not in the large intestine and pancreas tissue