30 research outputs found
Study of diffusion in copper chromite catalyst under reaction conditions
This article does not have an abstract
Prevalence and burden of HBV co-infection among people living with HIV:A global systematic review and meta-analysis
Globally, in 2017 35 million people were living with HIV (PLHIV) and 257 million had chronic HBV infection (HBsAg positive). The extent of HIV-HBsAg co-infection is unknown. We undertook a systematic review to estimate the global burden of HBsAg co-infection in PLHIV. We searched MEDLINE, Embase and other databases for published studies (2002-2018) measuring prevalence of HBsAg among PLHIV. The review was registered with PROSPERO (#CRD42019123388). Populations were categorized by HIV-exposure category. The global burden of co-infection was estimated by applying regional co-infection prevalence estimates to UNAIDS estimates of PLHIV. We conducted a meta-analysis to estimate the odds of HBsAg among PLHIV compared to HIV-negative individuals. We identified 506 estimates (475 studies) of HIV-HBsAg co-infection prevalence from 80/195 (41.0%) countries. Globally, the prevalence of HIV-HBsAg co-infection is 7.6% (IQR 5.6%-12.1%) in PLHIV, or 2.7 million HIV-HBsAg co-infections (IQR 2.0-4.2). The greatest burden (69% of cases; 1.9 million) is in sub-Saharan Africa. Globally, there was little difference in prevalence of HIV-HBsAg co-infection by population group (approximately 6%-7%), but it was slightly higher among people who inject drugs (11.8% IQR 6.0%-16.9%). Odds of HBsAg infection were 1.4 times higher among PLHIV compared to HIV-negative individuals. There is therefore, a high global burden of HIV-HBsAg co-infection, especially in sub-Saharan Africa. Key prevention strategies include infant HBV vaccination, including a timely birth-dose. Findings also highlight the importance of targeting PLHIV, especially high-risk groups for testing, catch-up HBV vaccination and other preventative interventions. The global scale-up of antiretroviral therapy (ART) for PLHIV using a tenofovir-based ART regimen provides an opportunity to simultaneously treat those with HBV co-infection, and in pregnant women to also reduce mother-to-child transmission of HBV alongside HIV
Selective laser melting of magnesium and magnesium alloy powders: A review
10.3390/met7010002Metals71
Enhancing the ignition, hardness and compressive response of magnesium by reinforcing with hollow glass microballoons
10.3390/ma10090997Materials10999
Magnesium-?-tricalcium phosphate composites as a potential orthopedic implant: A mechanical/damping/immersion perspective
10.3390/met8050343Metals8534
A fatal case of empyema thoracis by Nocardia farcinica in an immunocompromised patient
Empyema thoracis by Nocardia farcinica infection is uncommon. Here we
report a rare and fatal infection in a 27-year-old HIV- seropositive
male who presented with cough, expectoration, and breathlessness.
Nocardia farcinica was isolated from sputum and pus from the pleural
cavity. Confirmation of the isolate and minimum inhibitory
concentrations (MIC) for various antibiotics was done at the Aerobic
Actinomycetes Reference Laboratory, Centres for Disease Control and
Prevention (CDC), Atlanta. Patient was treated with suitable
antibiotics and antiretroviral drugs in spite of which he eventually
succumbed to the disease
Enhancing the hardness and compressive response of magnesium using complex composition alloy reinforcement
10.3390/met8040276Metals8427