7 research outputs found

    Essential Oil of Betula pendula Roth. Buds

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    The essential oil of Betula pendula Roth. buds was obtained using both hydrodistillation and microdistillation techniques and their chemical compositions were analyzed using both gas chromatography (GC) and gas chromatography–mass spectrometry (GC-MS). Overall, more than 50 compounds were identified representing 80% and 92% for hydrodistillation and microdistillation, respectively. The main components (by hydrodistillation and microdistillation, respectively) found were α-copaene (12% and 10%), germacrene D (11% and 18%) and δ-cadinene (11% and 15%) in the analyzed essential oils. The microdistillation technique proved to be a useful tool and compliant alternative when compared to hydrodistillation

    LaPSvS1, a (1→3)-β-galactan sulfate and its effect on angiogenesis in vivo and in vitro

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    LaPSvS1, a highly sulfated branched (1→3)-β-galactan was prepared from the arabino-galactan from Larix decidua Miller by partial hydrolysis and subsequent sulfation with SO3-pyridine in DMF. The molecular weight was analyzed by GPC and the sulfate content was determined by ion chromatography. LaPSvS1 exhibited good antiangiogenic and antiinflammatory effects in two different modifications of the known CAM-assay. In vitro results obtained in the FGF-2-trypsin-assay and in fluorospectrometric experiments revealed that LaPSvS1 interacts with the fibroblast growth factor 2 system. This interaction is correlated with the in vivo effect of LaPSvS1 on FGF-2 induced angiogenesis. A highly sulfated branched (1→3)-β-galactan (LaPSvS1) exhibits good antiangiogenic and antiinflammatory effects in CAM-assays. In vitro results reveal that LaPSvS1 interacts with the FGF-2 system correlating with the in vivo effect of LaPSvS1 on FGF-2 induced angiogenesis

    Sulfemodin 8- O

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