136 research outputs found

    Evolution of the BFQ Storage-I/O scheduler

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    An accurate storage-I/O scheduler, named Budget Fair Queueing (BFQ), was integrated with a special set of heuristics a few years ago. The resulting, improved scheduler, codenamed BFQ-v1, was able to guarantee a number of desirable service properties, including a high responsiveness, to applications and system services. In the intervening years, BFQ-v1 has become relatively popular on desktop and handheld systems, and has further evolved. But no official, comprehensive and concentrated documentation has been provided about the improvements that have followed each other. In this paper we fill this documentation gap, by describing the current, last version of BFQ (v7r8). We also show the performance of BFQ-v7r8 through some experimental results, in terms of throughput and application responsiveness, and on both an HDD and an SSD

    940-73 Predictive Value for Major Arrhythmic Events of Ventricular Arrhythmias Detected in the Subacute Phase of a Fibrinolysed Myocardial Infarction. An Analysis of the GISSI-2 Data Base

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    The relationship between ventricular arrhythmias (VA) in the subacute phase of a myocardial infarction and subsequent major arrhythmic events (MAE) was mainly defined in the prefibrinolytic era, We examined the large population of patients enrolled in the GISSI-2 study in order to evaluate the significance and predictive power for MAE (sustained ventricular tachycardia -SVT-and sudden death -SD-) of VA detected by Holter monitoring during the subacute phase of a fibrinolysed acute myocardial infarction (AMI). Of the 12,381 pts. enrolled in the GISSI-2 study, an Holter monitoring was available in 8,676 and a six month follow-up was completed in 7,713. During the follow-up 84 pts. died suddenly and 26 experienced one or more SVT. The relationship between VA and MAE was evaluated by odds ratio (OR) and their 95% confidence intervals. OR for MAE was 4.5 (2.7–7.5) if the Holter showed > 10 ventricular ectopic beats per hour; 2.3 (1.5–3.7) if couplets were present; 3.3 (1.5–7.0) if nonsustained ventricular tachycardias (NSVT) were noticed; 3.0 12.0–4.5) if any complex VA was detected. A multivariate analysis (Cox modell including the major prognostic determinants confirmed the independent prognostic value of VA in the Holter recording except for NSVT. Any arrhythmic parameter had a very low positive predictive power (from 2.4 to 3.0%). In conclusion, our data show that VA still have, in the fibrinolytic era, a prognostic significance for MAE, but the predictive power is very low and is therefore mandatory to add other variables to identify the pts. more at risk

    Human footprints from Italy: the state of the art

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    The ichnological record of human traces from Italy is rich and quite diversified. In recent years, the development and dissemination of various methodologies and technological facilities has implemented the re-analysis of this record, enabling to reach different, sometimes deeper, interpretations favoured by the integration of external data, both geological and palaeontological. The oldest occurrence of the human ichnological record from Italy is represented by the Middle Pleistocene ‘Devil’s Trails’ ichnosite in the “Foresta” area (Roccamonfina volcano, southern Italy), depicting human trackmakers trampling a pyroclastic flow deposit while descending a slope about 349 ka. Most of the record is Holocene in age and is constituted by the Upper Palaeolithic Grotta della BĂ sura site (Toirano, northern Italy, about 14 ky), the protohistoric sites of Afragola, Nola and Palma, the area of Pompei and the site of Aosta. The record is enriched by the ichnological evidences preserved in military structures of Trentino region (northern Italy) during the First World War. An updated report and discussion of these sites is here provided.Fil: Avanzini, Marco. Museo Delle Scienze di Trento; ItaliaFil: Citton, Paolo. Consejo Nacional de Investigaciones CientĂ­ficas y TĂ©cnicas; Argentina. Universidad Nacional de RĂ­o Negro. Sede Alto Valle. Instituto de Investigaciones en PaleobiologĂ­a y GeologĂ­a; ArgentinaFil: Mietto, Paolo. UniversitĂ  di Padova; ItaliaFil: Panarello, Adolfo. UniversitĂ  di Cassino e del Lazio Meridionale; ItaliaFil: Raia, Pasquale. UniversitĂ  degli Studi di Napoli Federico II; ItaliaFil: Romano, Marco. UniversitĂ  di Roma; ItaliaFil: Salvador, Isabella. Museo Delle Scienze di Trento; Itali

    Centrotemporal spikes during NREM sleep: The promoting action of thalamus revealed by simultaneous EEG and fMRI coregistration

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    Benign childhood epilepsy with centrotemporal spikes (BECTS) has been investigated through EEG\u2013fMRI with the aim of localizing the generators of the epileptic activity, revealing, in most cases, the activation of the sensory\u2013motor cortex ipsilateral to the centrotemporal spikes (CTS). In this case report, we investigated the brain circuits hemodynamically involved by CTS recorded during wakefulness and sleep in one boy with CTS and a language disorder but without epilepsy. For this purpose, the patient underwent EEG\u2013fMRI coregistration. During the \u201cawake session\u201d, fMRI analysis of right-sided CTS showed increments of BOLD signal in the bilateral sensory\u2013motor cortex. During the \u201csleep session\u201d, BOLD increments related to right-sided CTS were observed in a widespread bilateral cortical\u2013subcortical network involving the thalamus, basal ganglia, sensory\u2013motor cortex, perisylvian cortex, and cerebellum. In this patient, who fulfilled neither the diagnostic criteria for BECTS nor that for electrical status epilepticus in sleep (ESES), the transition from wakefulness to sleep was related to the involvement of a widespread cortical\u2013subcortical network related to CTS. In particular, the involvement of a thalamic\u2013perisylvian neural network similar to the one previously observed in patients with ESES suggests a common sleep-related network dysfunction even in cases with milder phenotypes without seizures. This finding, if confirmed in a larger cohort of patients, could have relevant therapeutic implication

    Validity and reliability of the Questionnaire of Olfactory Disorders for Italian-speaking patients with olfactory dysfunction

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    Objective: To translate and validate an Italian version of the Questionnaire of Olfactory Disorders (IT-QOD). Materials and methods: This is a prospective, multicentre study that involved patients with olfactory dysfunction (OD). Both cases and controls underwent administration of the IT-QOD, Sino-Nasal Outcome Test-22 (SNOT-22) and psychophysical evaluation of orthonasal and retronasal olfactory function. Results: The IT-QOD was administered to 96 patients and 38 controls. The Cronbach's alpha exceeded 0.90, indicating satisfactory internal consistency. The test-retest reliability was found to be high for both parosmia (rs = 0.944) and life quality (rs = 0.969). Patients with OD had significantly higher IT-QOD scores compared to healthy individuals (p < 0.001), indicating strong internal validity. The external validity was also satisfactory, as shown by the significant correlation with SNOT-22 (rs = -0.54) and the threshold, discrimination, and identification score (rs = -0.63). Conclusions: The IT-QOD was demonstrated to be reliable and valid to assess the impact of OD on the quality of life of Italian-speaking patients

    Icno-archeology of a human palaeolithic ecosystem: The human and animal footprints in the Grotta Della Basura (Toirano, Northern Italy)

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    The footprints of human and animal trackmakers, which around 12,000 years B.P. attended the Cave of B\ue1sura (Toirano, Liguria, Northern Italy), were studied through morpho-classificatory and morphometric approaches. First results indicate at least three different human producers, two youths and the third of tender age, bears and wolves (or dogs). Analysis of the data demonstrate the power of 3D, of landmark based morphometrics and the utility to use the methods of forensic anthropology in the determination of human foot-prints. The analysis of the number of trackmakers using the PCA analysis on 'multi-trampling' surfaces could represent a model in the study of cave sites

    Pheochromocytomas and paragangliomas in children: Data from the Italian Cooperative Study (TREP)

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    Pheochromocytomas (PCs) are neuroendocrine tumors arising from the chromaffin cells of the adrenal gland, and paragangliomas (PGLs) are their extra-adrenal counterparts arising from ganglia along the sympathetic/parasympathetic chain. Surgery is the cornerstone of treatment. A sporatic or inherited germline mutation is commonly associated
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