7 research outputs found

    Mechanisms regulating skin immunity and inflammation

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    Immune responses in the skin are important for host defence against pathogenic microorganisms. However, dysregulated immune reactions can cause chronic inflammatory skin diseases. Extensive crosstalk between the different cellular and microbial components of the skin regulates local immune responses to ensure efficient host defence, to maintain and restore homeostasis, and to prevent chronic disease. In this Review, we discuss recent findings that highlight the complex regulatory networks that control skin immunity, and we provide new paradigms for the mechanisms that regulate skin immune responses in host defence and in chronic inflammation

    A synoptic overview of golden jackal parasites reveals high diversity of species

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    Apoptosis and necroptosis in the liver: a matter of life and death

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    Cell death in chronic inflammation: breaking the cycle to treat rheumatic disease

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