HENOCH-SCHONLIEN PURPURA ASSOCIATED WITH HEPATITIS C AND COMPENSATED CIRRHOSIS

An unordinary case report of henoch-schonlein purpura (HSP) in a relationship with hepatitis C and compensated cirrhosis was identified in 14 y aged male patient. He was admitted in the pediatric department with stomach pain, yellow skin, rashes with tingling and erythematous injuries over the legs with agony and swelling since multi-day. He feels pain during walking and appears to be with swelling of lower leg muscles. His unusual liver function test was distinguished with elevated levels of bilirubin-3 mg/dl, basic phosphatase-314 U/l, aspartate aminotransferase-55 U/l and alanine aminotransferase-60 U/l. His skin biopsy shows up leukocytoclastic vasculitis and IgA depositions. Liver biopsy revealed nuclei enlargement with extensive cell change and scattered cell plates. His blood test was with the presence of the hepatitis C virus (HCV) antibodies. He was finally diagnosed as HSP associated with HCV and compensated cirrhosis

A CASE REPORT ON ISOLATED HEMATURIA WITH ANEMIA DUE TO SCHISTOSOMA HAEMATOBIUM

An unsual case in India was reported with an Isolated Hematuria with Anemia due to Schistosoma Haematobium. A male North African patient aged with 22 years admitted in hospital in Hyderabad with chief complaints of hematuria with dysuria, fever with night sweats and shortness of breath during exercise. His skin appears as pale. His history known that he came to India for his academics. He has a habit of swimming in lake at his country. He has no known past medical history and medication history. His blood reports were found to be low hemoglobin levels and low RBC count. His urine analysis results with reddish colored erythrocytes and crystals with an absence of proteins and casts. Microscopic examination of urine detects Schistosoma Haematobium eggs by using repeated concentration techniques

ALENDRONATE-INDUCED RESPIRATORY DISTRESS

Respiratory distress is a rare adverse effect of alendronate that is typically associated with severe dyspnoea and wheezing and typically requires hospitalization. The patient with a history of dyspnoea and wheezing during the strenuous workload was treated promptly with alendronate for newly diagnosed osteoporosis. After 2 days, respiratory distress complications were restarted and we accurately reported the patient with basophilia, elevated immunoglobulin E (with a blood test), and allergic bronchopulmonary aspergillosis (with computed tomography scan image). The prospective patient was adequately understood as alendronate-induced respiratory distress with an unfortunate rechallenge method. Although there is no direct causal relationship from this adverse case report, the possible mechanism has discussed typically based on peer-reviewed literature

A REVIEW NOVEL CORONAVIRUS

Coronaviruses (CoVs), incorporated positive-sense RNA diseases, are depicted by the club-like spikes that adventure from their surface, an abnormally huge RNA genome, and a specific replication technique. CoVs cause a selection of diseases in mammals and birds ranging from enteritis in cows and pigs and upper respiratory sickness in chickens too possibly deadly human respiratory diseases. Here, we provide a quick presentation to CoVs talking about their replication and pathogenicity, and current avoidance and treatment techniques. We likewise mention the episodes of the profoundly pathogenic severe acute respiratory syndrome CoV (SARS-CoV) and thus the recently identify Middle Eastern respiratory syndrome CoV (MERS-CoV)