29 research outputs found
Pre- and post-radiotherapy MRI results as a predictive model for response in laryngeal carcinoma
Avaliação por tomografia computadorizada do envolvimento loco-regional do carcinoma espinocelular de corda vocal
Reliability of Interpretation of CT Examination of the Larynx in Patients with Glottic Laryngeal Carcinoma
The importance of actual tumor growth rate on disease free survival and overall survival in laryngeal squamous cell carcinoma
Prostate tumor delineation using multiparametric magnetic resonance imaging : Inter-observer variability and pathology validation
Background and purpose: Boosting the dose to the largest (dominant) lesion in radiotherapy of prostate cancer may improve treatment outcome. The success of this approach relies on the detection and delineation of tumors. The agreement among teams of radiation oncologists and radiologists delineating lesions on multiparametric magnetic resonance imaging (mp-MRI) was assessed by measuring the distances between observer contours. The accuracy of detection and delineation was determined using whole-mount histopathology specimens as reference. Material and methods: Six observer teams delineated tumors on mp-MRI of 20 prostate cancer patients who underwent a prostatectomy. To assess the inter-observer agreement, the inter-observer standard deviation (SD) of the contours was calculated for tumor sites which were identified by all teams. Results: Eighteen of 89 lesions were identified by all teams, all were dominant lesions. The median histological volume of these was 2.4 cm(3). The median inter-observer SD of the delineations was 0.23 cm. Sixty-six of 69 satellites were missed by all teams. Conclusion: Since all teams identify most dominant lesions, dose escalation to the dominant lesion is feasible. Sufficient dose to the whole prostate may need to be maintained to prevent under treatment of smaller lesions and undetected parts of larger lesions. (C) 2015 The Authors. Published by Elsevier Ireland Ltd
Prognostic Value of Cartilage Sclerosis in Laryngeal Cancer Treated with Primary Radiation Therapy
The relationship between nasopharyngeal carcinoma tumor volume and TNM T-classification: A quantitative analysis
10.1007/s00405-006-0163-2European Archives of Oto-Rhino-Laryngology2642169-174EAOT