10 research outputs found

    Quiet in the Operating Room! Team STEPPS and OR Distractions

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    Background and Objective: From the moment that a patient enters the operating room to the time that they are brought to the post anesthesia care unit, a distraction has the potential to lead to an adverse outcome for the patient. During the critical portions of the surgery, it is even more important for all members of the operating staff to be focused and engaging in safe practices. Distractions in the operating room can hinder safe communication and potentially endanger patient safety. Team training has been shown to both improve team communication and reduce distractions. The objective of this project was using Team STEPPS training to reduce distractions during the critical portions of surgery, defined as the time of anesthesia induction, the time out, and the time of emergence from anesthesiahttps://jdc.jefferson.edu/patientsafetyposters/1060/thumbnail.jp

    Thoracostomy Tube Placement: Resident Experience and Confidence at a Large Academic Medical Center

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    The goal of this study was to investigate TT placement patterns and resident confidence at one academic medical center. In addition, our second objective was to gather quantitative data on the frequency and context of TT placement, rates of complications, and factors associated with complications among residents at TJUH

    Surgical Apgar Score (SAS) Predicts Perioperative Morbidity and Length of Stay in Patients Undergoing Esophagectomy at a High-Volume Center

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    Background: Esophagectomy is a procedure that carries considerable morbidity. Many studies have evaluated factors to predict patients at risk and improve clinical outcomes. The aim of this study was to determine whether the SAS predicts complications, length of stay, and anastomotic leak for patients undergoing esophagectomy at a high-volume institution.https://jdc.jefferson.edu/surgeryposters/1002/thumbnail.jp

    The Caenorhabditis elegans Elongator Complex Regulates Neuronal α-tubulin Acetylation

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    Although acetylated α-tubulin is known to be a marker of stable microtubules in neurons, precise factors that regulate α-tubulin acetylation are, to date, largely unknown. Therefore, a genetic screen was employed in the nematode Caenorhabditis elegans that identified the Elongator complex as a possible regulator of α-tubulin acetylation. Detailed characterization of mutant animals revealed that the acetyltransferase activity of the Elongator is indeed required for correct acetylation of microtubules and for neuronal development. Moreover, the velocity of vesicles on microtubules was affected by mutations in Elongator. Elongator mutants also displayed defects in neurotransmitter levels. Furthermore, acetylation of α-tubulin was shown to act as a novel signal for the fine-tuning of microtubules dynamics by modulating α-tubulin turnover, which in turn affected neuronal shape. Given that mutations in the acetyltransferase subunit of the Elongator (Elp3) and in a scaffold subunit (Elp1) have previously been linked to human neurodegenerative diseases, namely Amyotrophic Lateral Sclerosis and Familial Dysautonomia respectively highlights the importance of this work and offers new insights to understand their etiology

    Magnetic Sphincter Augmentation for Chronic GERD

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    Surgical Lifeline: A Surgeon\u27s Framework for the Unplanned Intraoperative Consultation

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    This is the result of: Review of the sparse literature on the topic A few years of observation and practice Conversation with many senior surgeon

    Department of Surgery Town Hall

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    Agenda New Faculty Departing Faculty Recent Appointments and Promotions Introducing Multi-Service Line Administrator: Adam Messer Fox Chase Comprehensive Cancer Center New Ambulatory Building - 1101 Chestnut Planned Biomedical Research Building Accomplishments of the Department of Surgery Advanced Practice Providers Enterprise Initiatives: Service Lines Campus Security Financial Year-to-Date Recent scholarly work by residents Gibbon 4 Resident Space PA Healthcare Usage Repor

    Supradiaphragmatic origin of the celiac trunk leading to median arcuate ligament syndrome with superior mesenteric artery involvement

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    Median arcuate ligament (MAL) syndrome (MALS) is a rare condition caused by compression of the celiac artery by the MAL. Symptoms include abdominal pain, nausea, and weight loss. Rarely, the MAL can compress both the celiac artery and the superior mesenteric artery (SMA). We describe the case of a young man with MALS involving the celiac artery and SMA. Laparoscopic release of the MAL was performed, and the patient had resolution of his symptoms at 6 months of follow-up. A review of the literature identified only six cases of MALS involving the SMA and celiac artery, making this a rare occurrence

    One-Year Health Care Utilization and Recurrence After Incisional Hernia Repair in the United States: A Population-Based Study Using the Nationwide Readmission Database.

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    BACKGROUND: Most data on health care utilization after incisional hernia (IH) repair are limited to 30-days and are not nationally representative. We sought to describe nationwide 1-year readmission burden after IH repair (IHR). METHODS: Patients undergoing elective IHR discharged alive were identified using the 2010-2014 Nationwide Readmission Database. Transfers and incomplete follow-up were excluded. Descriptive statistics were used to describe rates of 1-year readmission, IH recurrence, and bowel obstruction. Cox regression allowed identification of factors associated with 1-year readmissions. Generalized linear models were used to estimate predicted mean difference in cumulative costs/year, which allowed estimation of IHR readmission costs/year nationwide. RESULTS: Of 15,935 identified patients, 19.35% were readmitted within 1 y. Patients who were readmitted differed by insurance, Charlson index, illness severity, smoking status, disposition, and surgical approach compared with those who were not (P \u3c 0.05). Of readmitted patients, 39.3% returned within 30 d; 50.9% and 25.6% were due to any and infectious complications, respectively; 25.6% presented to a different hospital; 35.4% required reoperation; 5.4% experienced bowel obstruction; and 5% had IHR revision. Factors associated with readmissions included Medicare (hazard ratio [HR] 1.46 [95% confidence interval 1.19-1.8]; P \u3c 0.01) or Medicaid (HR 1.42 [1.12-1.8], P \u3c 0.01); chronic pulmonary disease (1.38 [1.17-1.64], P \u3c 0.01), and anemia (1.36, [1.05-1.75], P = 0.02). Readmitted patients had higher 1-year cumulative costs (predicted mean difference 12,190[9512,190 [95% CI: 10,941-13,438]; P \u3c 0.01). Nationwide cost related to readmissions totaled 90,196,248/y. CONCLUSIONS: One-year readmissions after IHR are prevalent and most commonly due to postoperative complications, especially infections. One-third of readmitted patients require a subsequent operation, and 5% experience IH recurrence, intensifying the burden to patients and on the health care system

    Soft Dynamic Confinement of Membrane Proteins by Dehydrated Trehalose Matrices: High-Field EPR and Fast-Laser Studies

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