VOICE RECOGNIZATION FOR MOUSE CONTROL USING HCI

One  of  the  most  important  research  areas  in  the  field  of  Human -Computer-Interaction (HCI) is gesture  recognition as it provides a natural and intuitive  way  to  communicate  between  people  and  machines.  Voice-based HCI applications range from computer applications to virtual/augmented reality and is recently being explored in other fields. This work proposes the implementation of absolute virtual mouse based on the interpretation of voice reorganization control. The procedure is to control the mouse pointer as for the mouse movement to up/down/left/right, open the file, dragging the file. This  virtual  device  is designed  specifically  as  an  alternative non-contact  pointer  for  people  with mobility impairments in the upper extremities. The implementation of the virtual mouse by voice control is to make HCI simplification for disabled persons especially for the person who are not having the hands and arms, and Alternative mouse cursor positioning system for laptops

Formulation and Evaluation of Lornoxicam Niosomal Topical Gel

A chronic illness has been mostly accomplished by delivery of drugs to patients using various pharmaceutical conventional dosage forms (such as tablets, capsules, pills, suppositories, creams, ointments, liquids, aerosols and injectables as drug carriers) (Chien Yie.W, 2005). Even today conventional drug delivery system occupies most of the part in a prescription as well as drug store. This type of drug delivery system is known to provide a prompt release of drug. Therefore, to achieve as well as to maintain the drug concentration within the therapeutically effective range needed for treatment, it is often necessary to take this type of drug delivery system several times a day (Chien Yie.W, 2005). study it is concluded that the niosomes can be considered as promising drug delivery vehicles which increase the duration of the drugs. Thus niosomes help in formulating dosage forms having more prolonged action. The niosomal delivery of lornoxicam in carbopol gel base acts as a suitable topical drug delivery system which may be given safely to all patients suffering from rheumatoid arthritis and osteoarthritis. The stability of niosomes improved after incorporation into gel base may be due to prevention of fusion of niosomes. Further the pharmacokinetic and other clinical studies may be carried out in future

Strain dependent & selective modulation of murine humoral immune response by carrageenan

Carrageenan (CGN), a polygalactan extracted from red algae, induced 90 per cent suppression of antibody response to sheep red blood cells in Balb/C strain as compared to the untreated controls. Whereas the treatment failed to induce suppression in C57BL/6 strain. The observed suppression of antibody response was significant on all days tested (up to 40 days) and the suppression induced by CGN was real and not due to any direct effect on antigen or on the assay system followed. On the other hand, as evident from foot-pad thickness, the delayed type hypersensitivity (DTH) was unaltered in Balb/C strain after CGN treatment

SUPPORTING DYNAMIC NETWORK SLICING AND POLICY CREATION FOR END DEVICES IN PRIVATE 5G NETWORKS

Described herein are techniques for handling dynamic slicing requirements of User Equipment (UE) by performing remote activation (e.g., Over-the-Air Provisioning (OTAP)) of the logical profiles captured in the embedded Subscriber Identity Module (eSIM) which are created for the different slicing needs in private 5G networks. Also described are techniques for installing policies based on the Manufacturer Usage Description (MUD) Uniform Resource Locator (URL) in a private 5G network and efficiently retaining it during a 5G outage

Comparative studies on mydriatic effect of tropicamide 0.8% and phenylephrin 5.0% in teenagers & geriatric people

Prospective study on the comparison of mydiriatic effect of Tropicamide 0.8% and Phenylephrine 5% in teenagers and geriatric people was carried out in suthrama Eye Hospital madanapalle, India. The main objective of this study was to compare the mydriatic effect of a combination of drug in teenagers and geriatric people. It also evaluated the ADR’s produced and the efficacy of the drug in two age groups. In this study population majority of the subjects were female in group A and male in group B. Among the whole population under study in group A and B no one has reported with any case of congenital anomalies. A number of ADR’s are reported but no serious adverse events had occurred. The study was carried out in 100 eyes ie. 50 subjects whom are divided into 2 groups based on age. The comparison of mydriatic effect was done in each group after instilling one drop of a combination of 0.08% Tropicamide and 0.5% Phenynilephrine. The pupillary size where measured before and after administration of drug and the results were compared. The results showed that there is a large difference in the normal pupil size between teenagers and geriatric people. After dilation the difference in pupil size was statistically significant among the two groups. The study concludes that the pupillary dilation produced by administering 0.8% Tropicamide and 5% Phenylephrine produces higher mydriatic effect in teenagers than geriatric people

An assessment of facility-based care of diabetes, hypertension, and heart failure across western Kenya

Background: Low- and middle- income countries account for three-fourths of the global non- communicable disease related mortality. In response to the increasing number of non- communicable disease diagnoses in Kenya, the government released a national strategy for non- communicable disease in 2015. The purpose of this study was to assess facility-based care of diabetes, hypertension, and heart failure across western Kenya.Methods: A 71-question cross-sectional survey was administered among facility-based healthcare workers in Siaya County, western Kenya, between October 2015 and January 2016. All Level 4 and 5 facilities, as well as a cohort of lower-level facilities were surveyed.Results: Of the 21 health facilities surveyed, six (31.6%) had specific non-communicable disease clinics. Eleven of the 21 (52.4%) facilities had glucometers, and providers indicated that even these glucometers were often not functional. Three of the 21 facilities (14.3%) had a diabetic registry, one a functioning electrocardiogram machine, and one other a congestive heart failure registry.Conclusions: Facilities at every level were lacking equipment and medications expected by the Kenya’s Essential Package of Health Services. Improvement for follow up and referral services could be achieved through the development of comprehensive non-communicable disease registries

Are taxane based regimens better than non-taxane fluoropyrimidine based regimens in advanced gastric cancer? Findings from an observational multicentre study, South India

Background: Capecitabine, 5 Fluorouracil, platinum agents and taxanes are either used alone or in combination in advanced gastric cancers (AGC). Data on tolerability and efficacy of these regimens are minimal. We aimed to report proportion of AGC patients opting for best supportive care upfront and tolerability and efficacy of taxane and non-taxane fluoropyrimidine based regimens from three oncology centers, South India.Methods: Case records of AGC patients initiated on either taxane or non-taxane fluoropyrimidine based chemotherapy during May 2016 to Dec 2017 in three private tertiary cancer care centers across two states in south India were reviewed. Information on clinical characteristics, regimen used, radiological and clinical response, toxicity and its related hospital admissions were extracted. Statistical analysis was done by categorical variables that were summarized using proportions. Median survival was calculated using Kaplan Meier curves and comparison between the groups were done using log-rank test.Results: Of 88 AGC patients, 27 patients (30.7%) opted for best supportive care; 19 and 41 patients received paclitaxel based and non-taxane fluoropyrimidine based regimens respectively. There was no statistically significant difference in pain symptoms, vomiting, hospital admissions and intensive care admissions between the two regimens. Median (inter quartile range) survival of patients receiving best supportive care, taxane based regimen and non-taxane fluoropyrimidine regimen were 3.1 (1.5-16.1), 7.4 (1.6-15.0) and 11.6 (3.2-29.3) months respectively. Median (range) survival on any chemotherapy was 10.3 (1.6-29.3) months and it was significantly higher compared to best supportive care (p<0.001)Conclusions: AGC patients on chemotherapy had improved overall survival compared to stand alone best supportive care. Fluoropyrimidine based regimens offered better survival than taxane based regimen

Evaluation of pharmacological activity of chadraprabha vati on serum of albino wistar strain rats

The current study is to develop the acute and sub-acute toxicity profile of some ayurvedic Bhasma and un-derstand the side effects due to the presence of heavy metals. Chandraprabha vati pill were weighed, powdery and suspended in water had made into liquid formulation. The animals were classified and treated with the doses of Chandraprabha vati (50and five hundred mg/kg) in rat. The dose was calculat-ed by extrapolating the equivalent human dose (1 and ten times) and was administered orally between ten and eleven after median daily for twenty eight days, during alylin a very volume not exceeding one ml/100 g rat weight. Blood was collected on seven, fourteen and twenty eight days, later they were sacri-ficed for histopathological studies