Comparison of haemodynamic parameters and recovery characteristics between sevoflurane and desflurane in patients undergoing day-care surgical procedure

Background: Smooth and rapid induction, optimal operating conditions and rapid recovery with minimal side effects such as nausea, vomiting, bleeding and post-operative pain are the characteristics of ideal anaesthetic. Objectives: The objective of the study was to compare the haemodynamic parameters and recovery characteristics of desflurane with sevoflurane. Materials and Methods: This was a prospective study conducted from January to December 2016. Using convenient sampling technique, a total of 40 adult patients of American Society of Anesthesiologists (ASA) physical status Grade I or II, aged between 18 and 60 years, of either sex, who were scheduled for elective day-care surgeries of <2 h duration under general anaesthesia were selected for the study after informed consent. All the patients were randomly allocated into one of the two groups using computer-generated random number table. Group I received induction with sevoflurane, while Group II was induced desflurane. Results: The baseline demographic analysis showed that the two groups did not differ significantly in age, weight, sex, ASA grade and operative times. During the course of surgery, heart rate was significantly low in Group II at 25, 30, 40 and 45 min than in Group I. Systolic and diastolic blood pressure was significantly low in group Desflurane as compared to sevoflurane. Group I showed significantly higher time for spontaneous eye opening and recalling names and recognising surroundings and post-operative complications compared to Group II. Conclusion: Desflurane has significantly better haemodynamic stability, post-operative recovery and less post-operative complications compared to sevoflurane