23 research outputs found

    Concurrent Odontogenic Keratocyst and Odontoma: Report of an Unusual and Rare Entity

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    Hybrid lesions of jaws are rare entities defined as two different lesions co-occurring in the same location, with identical histopathological origin. Ameloblastoma, calcifying cystic odontogenic tumor and odontoma are among the most common lesions that have been reported to combine with other lesions. In this study, a hybrid lesion of odontogenic keratocyst (OKC) and odontoma in the mandible of a forty-five years old male reported. Additional to the rarity of this hybrid lesion, the present case had unique radiologic features, including atypical location and extension of the lesion and profound knife-edge root resorption of the teeth in the area, which was not a common feature for any of the two lesions. The surgical procedure was marsupialization to reduce the size of the lesion. As a result of the surgery, the healing of the surgical wound was uneventful. In addition, careful follow-up for the patient was conducted, which had no recurrence till now (after 15 months)

    Admittance Method for Estimating Local Field Potentials Generated in a Multi-Scale Neuron Model of the Hippocampus

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    Significant progress has been made toward model-based prediction of neral tissue activation in response to extracellular electrical stimulation, but challenges remain in the accurate and efficient estimation of distributed local field potentials (LFP). Analytical methods of estimating electric fields are a first-order approximation that may be suitable for model validation, but they are computationally expensive and cannot accurately capture boundary conditions in heterogeneous tissue. While there are many appropriate numerical methods of solving electric fields in neural tissue models, there isn\u27t an established standard for mesh geometry nor a well-known rule for handling any mismatch in spatial resolution. Moreover, the challenge of misalignment between current sources and mesh nodes in a finite-element or resistor-network method volume conduction model needs to be further investigated. Therefore, using a previously published and validated multi-scale model of the hippocampus, the authors have formulated an algorithm for LFP estimation, and by extension, bidirectional communication between discretized and numerically solved volume conduction models and biologically detailed neural circuit models constructed in NEURON. Development of this algorithm required that we assess meshes of (i) unstructured tetrahedral and grid-based hexahedral geometries as well as (ii) differing approaches for managing the spatial misalignment of current sources and mesh nodes. The resulting algorithm is validated through the comparison of Admittance Method predicted evoked potentials with analytically estimated LFPs. Establishing this method is a critical step toward closed-loop integration of volume conductor and NEURON models that could lead to substantial improvement of the predictive power of multi-scale stimulation models of cortical tissue. These models may be used to deepen our understanding of hippocampal pathologies and the identification of efficacious electroceutical treatments

    Lightning Electromagnetic Fields and Their Induced Currents on Buried Cables. Part I: The Effect of an Ocean-Land Mixed Propagation Path

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    We use a full-wave finite-element-based solution of Maxwell's equations for the evaluation of lightning electromagnetic fields inside a vertically stratified, two-layer ground (ocean-land mixed propagation path) and their induced currents on the shield of buried cables. For "normal" incidence (with respect to the ocean-land interface), it is shown that the vertical electric field is the component most affected by the ocean-land mixed path when the observation point is close to the ocean-land interface (i.e., 5 m or so). For "oblique" incidence, however, depending on the angle of incidence and the distance between the observation point and the ocean, all the field components are reduced by the ocean-land interface. For the calculation of induced currents, and for the case of a parallel layout (cable laying in parallel to the ocean-land interface); 1) for a strike to the land, when the cable is buried in the soil and the distance to the ocean is greater than about 100 m, the effect of the ocean is negligible. 2) For a strike to the ocean, the induced current magnitudes are appreciable only when the cable is entirely within the land. For the case of a perpendicular layout (cable perpendicular to the ocean-land interface); 1) for a strike to the ocean, when the cable is totally buried in the ocean, the effect of ocean-land mixed propagation is negligible. However, when the cable extends into the land through one end, the induced currents increase at both ends with increasing length of underland portion. 2) For a strike to the land, when the cable is located entirely inside the land, the effect of ocean-land mixed path on the induced currents at both ends is negligible. However, as the cable extends into the ocean, a remarkable enhancement in the induced currents is observed for the termination located inside the land. This enhancement can be as high as a factor of 2 with respect to the case of a cable in homogeneous soil characterized by the properties of the land

    Lightning Electromagnetic Fields and Their Induced Currents on Buried Cables. Part II: The Effect of a Horizontally Stratified Ground

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    We use a finite element method (FEM) to evaluate the effect of a horizontally stratified two-layer ground on underground lightning electromagnetic fields and their induced currents on the shield of buried cables. It is shown that the azimuthal component of the magnetic field in the upper soil layer is affected by the soil stratification only when this layer is more conductive than the lower soil layer. On the other hand, inside the lower soil layer, this component is always affected by the soil stratification. The vertical electric field in the upper soil layer is mainly determined by the conductivity of the same layer in particular at close observation points. However, this component inside a more conductive lower soil layer is identical to that corresponding to a homogeneous soil with the same property of the lower soil layer. The horizontal electric field inside a stratified ground always takes values in between the electric fields corresponding to one-layer homogenous grounds. We also present a comparison with available experimental data on induced currents of a shielded buried cable and show that, in agreement with recent studies, taking the soil stratification into account allows to improve the late-time response of the induced currents. We also show that the horizontal stratification of soil may result, in some cases, in an enhancement of the induced currents with respect to the case of a homogeneous ground characterized by the electrical properties of either of the two layers
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