17 research outputs found
Correlation between S-1 treatment outcome and expression of biomarkers for refractory thymic carcinoma
Effect of parthenin on mitochondrial oxidative phosphorylation
The sesquiterpene lactone, 'parthenin' the toxic principle of the allergenic weed Parthenium hysterophorus, inhibited 'state 3' respiration and stimulated 'state 4' respiration in rat liver and kidney mitochondria as well as ATPase activity in the presence of ions. These properties indicate that the toxic action of parthenin may be related to its interference with oxidative phosphorylation