Carbonate factory of Pietra di Finale coastal wedge (Miocene): the unusual abundance of stylasterids (Cnidaria, Hydrozoa)

This work focuses on the carbonate factories constituting the Pietra di Finale Fm cropping out in the Ligurian Alps. This unit constituted a mixed carbonate-siliciclastic coastal wedge developed during the Middle Miocene. The carbonate factories characterizing the coastal wedge of the Pietra di Finale clearly differ from those of the coastal mixed systems and carbonate platforms developing during the Miocene elsewhere in the Mediterranean area. Here, in the Ligurian Alps, the euphotic carbonate factory does not show any evidence of seagrass meadows and coral bioconstructions. Zooxanthellate corals are present only as skeletal debris associated with abundant stylasterids. In the mesophotic and oligophotic zones, the typical oligophotic biota of red algae and larger benthic foraminifers are strongly reduced. The coastal wedge of the Pietra di Finale shows an unusual abundance of stylasterids, classically interpreted as deep-water biota. However, in this example, the absence of low-energy textures and other skeletal components suggest a shallow-water origin, probably in the eu- or mesophotic zone. The stylasterids colonized the hard substrates available and were successively removed and resedimented to form the skeletal fraction of the coastal wedge of the Pietra di Finale. The abundance of stylasterids is restricted to particular and limited situations in the Miocene of the Mediterranean, thus suggesting that their abnormal development is controlled by local rather than global factors

Zanclea–coral association: new records from Maldives

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The development and neural basis of referential gaze perception

Infants are sensitive to the referential information conveyed by others’ eye gaze, which could be one of the developmental foundations of theory of mind. To investigate the neural correlates of gaze–object relations, we recorded ERPs from adults and 9-month-old infants while they watched scenes containing gaze shifts either towards or away from the location of a preceding object. In adults, object-incongruent gaze shifts elicited enhanced ERP amplitudes over the occipito-temporal area (N330). In infants, a similar posterior ERP component (N290) was greater for object-incongruent gaze shifts, which suggests that by the age of 9 months infants encode referential information of gaze in a similar way to adults. In addition, in infants we observed an early frontal ERP component (anterior N200), which showed higher amplitude in response to the perception of object-congruent gaze shifts. This component may reflect fast-track processing of socially relevant information, such as the detection of communicative or informative situations, and could form a developmental foundation for attention sharing, social learning and theory of mind

A Review of Issues Related to Data Acquisition and Analysis in EEG/MEG Studies

Electroencephalography (EEG) and magnetoencephalography (MEG) are non-invasive electrophysiological methods, which record electric potentials and magnetic fields due to electric currents in synchronously-active neurons. With MEG being more sensitive to neural activity from tangential currents and EEG being able to detect both radial and tangential sources, the two methods are complementary. Over the years, neurophysiological studies have changed considerably: high-density recordings are becoming de rigueur; there is interest in both spontaneous and evoked activity; and sophisticated artifact detection and removal methods are available. Improved head models for source estimation have also increased the precision of the current estimates, particularly for EEG and combined EEG/MEG. Because of their complementarity, more investigators are beginning to perform simultaneous EEG/MEG studies to gain more complete information about neural activity. Given the increase in methodological complexity in EEG/MEG, it is important to gather data that are of high quality and that are as artifact free as possible. Here, we discuss some issues in data acquisition and analysis of EEG and MEG data. Practical considerations for different types of EEG and MEG studies are also discussed

Microfluidic system for a label-free, real-time functional assessment of thrombotic risk

High incidence of thrombotic diseases worldwide, together with the variability of patients’ response to antiplatelet drugs, makes the management of antithrombotic regimes of paramount importance. Platelet function testing is the most promising tool in addressing this clinical need. Here we present the first prototype of a microfluidic system for rapid, label-free, real-time functional assessment of the thrombotic risk of patients undergoing antiplatelet treatment. Our platform allows to monitor pressure drop variations on a collagen-coated microchannel under a range of blood flow conditions, and to relate these measurements to thrombus formation and ultimately to platelet functionality. The preliminary testing campaign presented in this work demonstrated the feasibility of our approach and allowed us to determine the most suitable working range of the current system

A educação dramática na formação inicial de professores e educadores

As atividades de Educação Dramática convocam uma diversidade de possibilidades expressivas. Integradas no currículo de formação inicial de professores e educadores, os projetos de criação dramática, orientados para a performance, implicam, no seu processo criativo, um envolvimento grupal que deverá constituir matéria suficiente de análise e de avaliação por parte dos seus intervenientes em relação à sua própria participação e às relações interpares. O paradigma metodológico orientador do processo dramático-teatral a que nos remetemos assenta num modelo construtivista do processo educacional. Pelo seu caráter explorativo e experimental, a aprendizagem dramático-teatral deverá ser sustentada em estratégias colaborativas entre professor e aluno, implicando, para tal, a possibilidade de tomada de decisões partilhadas, num ambiente de respeito e igualdade.The activities of Drama Education are open to a diversity of expressive possibilities. Integrated in the pre-service training curriculum for teachers and educators, the dramatic creation projects, oriented to performance, imply, in its creative process, a group involvement that should be sufficient matter of analysis and evaluation by those involved in relation to its own participation and relations between peers. The methodological guidance paradigm of the dramatic and theatrical process that guide us is based on a constructivist model of the educational process. Due its exploratory and experimental character, dramatic and theatrical learning should be based on collaborative strategies between teacher and student, implying, to this end, that decision-making possibilities could be shared in an environment of respect and equality.CIEC - Centro de Investigação em Estudos da Criança, IE, UMinho (UI 317 da FCT), Portugal. Fundos Nacionais através da FCT (Fundação para a Ciência e a Tecnologia) e cofinanciado pelo Fundo Europeu de Desenvolvimento Regional (FEDER) através do COMPETE 2020 – Programa Operacional Competitividade e Internacionalização (POCI) com a referência POCI-01-0145-FEDER-007562info:eu-repo/semantics/publishedVersio

Spatial patterns and drivers of benthic community structure on the northern Adriatic biogenic reefs

The northern Adriatic Sea (NAS) hosts numerous biogenic subtidal reefs that are considered biodiversity hotspots. Several studies have already investigated the origin and biodiversity of these reefs. However, many of them are still unexplored and further knowledge is needed for their conservation. Here, the spatial variability, epibenthic community structure, and environmental features that characterize these habitats were investigated. Fifteen randomly selected reefs were sampled between 2013 and 2017, including some remote sites that have never been studied before. A fuzzy k-means clustering method and redundancy analysis were used to find similarities among sites in terms of epibenthic assemblages and to model relationships with abiotic variables. The results showed that these reefs are highly heterogeneous in terms of species composition and geomorphological features. The results were also consistent with previous studies and highlighted three main types of benthic assemblages defined by the dominance of different organisms, mainly reflecting the coastal-offshore gradient: nearshore reefs, generally dominated by stress-tolerant species; reefs at a middle distance from the coast, characterized by sponges, non-calcareous encrusting algae and ascidians; offshore reefs, dominated by reef builders. However, distance from the coast was not the only factor affecting species distribution, as other local factors and environmental characteristics also played a role. This kind of biogenic reefs in temperate seas are still poorly known. The present work contributed to shed further light on these habitats, by complementing the results of previous studies on their natural diversity, highlighting the specificity of the epibenthic communities of NAS reefs and the need to improve current, still inadequate, conservation measures

Planetary sleep medicine. Studying sleep at the individual, population, and planetary level

Circadian rhythms are a series of endogenous autonomous oscillators that are generated by the molecular circadian clock which coordinates and synchronizes internal time with the external environment in a 24-h daily cycle (that can also be shorter or longer than 24 h). Besides daily rhythms, there exist as well other biological rhythms that have different time scales, including seasonal and annual rhythms. Circadian and other biological rhythms deeply permeate human life, at any level, spanning from the molecular, subcellular, cellular, tissue, and organismal level to environmental exposures, and behavioral lifestyles. Humans are immersed in what has been called the “circadian landscape,“ with circadian rhythms being highly pervasive and ubiquitous, and affecting every ecosystem on the planet, from plants to insects, fishes, birds, mammals, and other animals. Anthropogenic behaviors have been producing a cascading and compounding series of effects, including detrimental impacts on human health. However, the effects of climate change on sleep have been relatively overlooked. In the present narrative review paper, we wanted to offer a way to re-read/re-think sleep medicine from a planetary health perspective. Climate change, through a complex series of either direct or indirect mechanisms, including (i) pollution- and poor air quality-induced oxygen saturation variability/hypoxia, (ii) changes in light conditions and increases in the nighttime, (iii) fluctuating temperatures, warmer values, and heat due to extreme weather, and (iv) psychological distress imposed by disasters (like floods, wildfires, droughts, hurricanes, and infectious outbreaks by emerging and reemerging pathogens) may contribute to inducing mismatches between internal time and external environment, and disrupting sleep, causing poor sleep quantity and quality and sleep disorders, such as insomnia, and sleep-related breathing issues, among others. Climate change will generate relevant costs and impact more vulnerable populations in underserved areas, thus widening already existing global geographic, age-, sex-, and gender-related inequalities

Dynamic pupillary exchange engages brain regions encoding social salience

Covert exchange of autonomic responses may shape social affective behavior, as observed in mirroring of pupillary responses during sadness processing. We examined how, independent of facial emotional expression, dynamic coherence between one's own and another's pupil size modulates regional brain activity. Fourteen subjects viewed pairs of eye stimuli while undergoing fMRI. Using continuous pupillometry biofeedback, the size of the observed pupils was varied, correlating positively or negatively with changes in participants’ own pupils. Viewing both static and dynamic stimuli activated right fusiform gyrus. Observing dynamically changing pupils activated STS and amygdala, regions engaged by non-static and salient facial features. Discordance between observed and observer's pupillary changes enhanced activity within bilateral anterior insula, left amygdala and anterior cingulate. In contrast, processing positively correlated pupils enhanced activity within left frontal operculum. Our findings suggest pupillary signals are monitored continuously during social interactions and that incongruent changes activate brain regions involved in tracking motivational salience and attentionally meaningful information. Naturalistically, dynamic coherence in pupillary change follows fluctuations in ambient light. Correspondingly, in social contexts discordant pupil response is likely to reflect divergence of dispositional state. Our data provide empirical evidence for an autonomically mediated extension of forward models of motor control into social interaction