11 research outputs found
Biopolymer Extracted from Anadenanthera colubrina (Red Angico Gum) Exerts Therapeutic Potential in Mice: Antidiarrheal Activity and Safety Assessment
Antinociceptive effects of the essential oil of Mentha x villosa leaf and its major constituent piperitenone oxide in mice
Chemical study and larvicidal activity against Aedes aegypti of essential oil of Piper aduncum L. (Piperaceae)
Prevalence and risk factors of psychiatric symptoms and diagnoses before and during the COVID-19 pandemic: findings from the ELSA-Brasil COVID-19 Mental Health Cohort
Background: There is mixed evidence on increasing rates of psychiatric disorders and symptoms during the coronavirus disease 2019 (COVID-19) pandemic in 2020. We evaluated pandemic-related psychopathology and psychiatry diagnoses and their determinants in the Brazilian Longitudinal Study of Health (ELSA-Brasil) SĂŁo Paulo Research Center.
Methods: Between pre-pandemic ELSA-Brasil assessments in 2008â2010 (wave-1), 2012â2014 (wave-2), 2016â2018 (wave-3) and three pandemic assessments in 2020 (COVID-19 waves in MayâJuly, JulyâSeptember, and OctoberâDecember), rates of common psychiatric symptoms, and depressive, anxiety, and common mental disorders (CMDs) were compared using the Clinical Interview Scheduled-Revised (CIS-R) and the Depression Anxiety Stress Scale-21 (DASS-21). Multivariable generalized linear models, adjusted by age, gender, educational level, and ethnicity identified variables associated with an elevated risk for mental disorders.
Results: In 2117 participants (mean age 62.3 years, 58.2% females), rates of CMDs and depressive disorders did not significantly change over time, oscillating from 23.5% to 21.1%, and 3.3% to 2.8%, respectively; whereas rate of anxiety disorders significantly decreased (2008â2010: 13.8%; 2016â2018: 9.8%; 2020: 8%). There was a decrease along three wave-COVID assessments for depression [ÎČ = â0.37, 99.5% confidence interval (CI) â0.50 to â0.23], anxiety (ÎČ = â0.37, 99.5% CI â0.48 to â0.26), and stress (ÎČ = â0.48, 99.5% CI â0.64 to â0.33) symptoms (all ps
Conclusion: No consistent evidence of pandemic-related worsening psychopathology in our cohort was found. Indeed, psychiatric symptoms slightly decreased along 2020. Risk factors representing socioeconomic disadvantages were associated with increased odds of psychiatric disorders.</p
Effects of inoculation by arbuscular mycorrhizal fungi on the composition of the essential oil, plant growth, and lipoxygenase activity of Piper aduncum L.
Clinopodium gilliesii (Benth.) Kuntze
Clinopodium gilliesii (Benth.) Kuntze is an aromatic species from the Andean region, from southern Peru to northern-central Argentina. It is mainly known as muña-muña and its leaves and tender stems are used as a flavoring and medicinal: stimulant, against mountain sickness, aphrodisiac, digestive, antispasmodic, among others traditional uses. Its bioactive constituents are essential oils, to which the plant owes its aroma and many of its therapeutic properties. The presence of flavonoids and phenolic compounds has also been detected. The essential oil composition of aerial organs is variable according to geographical location and ecological conditions, soil-type, weather-conditions and altitude of the population. Regarding its popular uses, the majority of uses has not been validate by pre-clinical tests, therefore they require experimental founding. Some of its biological activities, e.g.: aphrodisiac (in particular, erectile dysfunction), against some gastrointestinal disorders, antibacterial, antifungal, antiplasmodial, trypanocidal, insect repellent, antioxidant, and cytotoxic activities have already been analyzed. Some data about the similar species: C. bolivianum (Benth.) Kuntze and C. odorun (Griseb.) Harley is additionally commented.Fil: Hurrell, Julio Alberto. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Laboratorio de EtnobotĂĄnica y BotĂĄnica Aplicada; Argentin