Poison sedge can kill stock

POISON SEDGE was first suspected of being toxic to livestock in Western Australia nearly 80 years ago. Sudden deaths of sheep grazing areas on which poison sedge grew have been reported from many regions from Geraldton to Scott River. This article reports a case of poisoning in the field, and the experimental reproduction of poison sedge toxicity in pen-fed sheep

Positive patient experiences in an Australian integrative oncology centre

Background: The purpose of this study was to explore the experiences of cancer patients\u27 utilising complementary and integrative therapies (CIT) within integrative oncology centres across Western Australia.Methods: Across four locations 135 patients accessed CIT services whilst undergoing outpatient medical treatment for cancer. Of the 135 patients, 66 (61 ± 12 y; female n = 45; male n = 21) agreed to complete a personal accounts questionnaire consisting of open-ended questions designed to explore patients\u27 perceptions of CIT. All results were transcribed into nVivo (v9) and using thematic analysis, key themes were identified.Results: Of the 66 participants, 100% indicated they would recommend complementary therapies to other patients and 92% stated CIT would play a significant role in their future lifestyle . A mean score of 8 ± 1 indicated an improvement in participants\u27 perception of wellbeing following a CIT session. Three central themes were identified: empowerment, support and relaxation. Fourteen sub-themes were identified, with all themes clustered into a framework of multifaceted views held by cancer patients in relation to wellbeing, role of significant others and control.Conclusions: Exploration of patients\u27 experiences reveals uniformly positive results. One of the key merits of the environment created within the centres is patients are able to work through their cancer journey with an increased sense of empowerment, without placing them in opposition to conventional medical treatment. In order to effectively target integrative support services it is crucial to explore the experiences of patients in their own words and use those forms of expression to drive service delivery

Characteristics and quality of life of patients presenting to cancer support centres: Patient rated outcomes and use of complementary therapies

Background: In order to effectively target and provide individualised patient support strategies it is crucial to have a comprehensive picture of those presenting for services. The purpose of this study was to determine the characteristics and patient rated outcomes of individuals presenting to SolarisCare cancer support centres and their choices regarding complementary and integrated therapies (CIT).Methods: A cohort with a current or previous cancer diagnosis aged 18 - 87 years presenting to a SolarisCare centre during a 5-day period completed a questionnaire. Four SolarisCare centres participated in the trial including regional and metropolitan locations. Outcomes included medical and demographic characteristics, CIT variables and patient rated outcomes (PROs) including quality of life (QoL).Results: Of the 95 participants (70.3%) who completed the survey, the mean age was 60.5 years with 62% currently receiving treatment. Eighty percent of the sample had at least one other comorbid condition, with the most popular CIT being relaxation massage. Of the PROs, QoL was significantly lower than norms for the Australian population and other mixed cancer populations. No notable differences were seen between genders, however significantly poorer outcomes were found for the younger age group. Fifty percent of the population did not meet physical activity recommendations, and musculoskeletal symptoms explained between 25-27% of variance in QoL.Conclusions: A greater understanding of the health profiles of patients presenting to supportive care centres and their use of CIT, provides Western Australian health professionals with key information to ensure the safety of supportive care practices, as well as fosters optimal patient outcomes and enhances the integration of supportive care strategies within mainstream medical care

Microbial risk assessment of drinking water based on hydrodynamic modelling of pathogen concentrations in source water

Norovirus contamination of drinking water sources is an important cause of waterborne disease outbreaks. Knowledge on pathogen concentrations in source water is needed to assess the ability of a drinking water treatment plant (DWTP) to provide safe drinking water. However, pathogen enumeration in source water samples is often not sufficient to describe the source water quality. In this study, the norovirus concentrations were characterised at the contamination source, i.e. in sewage discharges. Then, the transport of norovirus within the water source (the river Gota alv in Sweden) under different loading conditions was simulated using a hydrodynamic model. Based on the estimated concentrations in source water, the required reduction of norovirus at the DWTP was calculated using quantitative microbial risk assessment (QMRA). The required reduction was compared with the estimated treatment performance at the DWTP. The average estimated concentration in source water varied between 4.8 x 10(2) and 7.5 x 10(3) genome equivalents L-1; and the average required reduction by treatment was between 7.6 and 8.8 Log(10). The treatment performance at the DWTP was estimated to be adequate to deal with all tested loading conditions, but was heavily dependent on chlorine disinfection, with the risk of poor reduction by conventional treatment and slow sand filtration. To our knowledge, this is the first article to employ discharge-based QMRA, combined with hydrodynamic modelling, in the context of drinking water. (C) 2015 Elsevier B.V. All rights reserved

A Toy Model for Blandford-Znajek Mechanism

A toy model for the Blandford-Znajek mechanism is investigated: a Kerr black hole with a toroidal electric current residing in a thin disk around the black hole. The toroidal electric current generates a poloidal magnetic field threading the black hole and disk. Due to the interaction of the magnetic field with remote charged particles, the rotation of the black hole and disk induces an electromotive force, which can power an astrophysical load at remote distance. The power of the black hole and disk is calculated. It is found that, for a wide range of parameters specifying the rotation of the black hole and the distribution of the electric current in the disk, the power of the disk exceeds the power of the black hole. The torque provided by the black hole and disk is also calculated. The torque of the disk is comparable to the torque of the black hole. As the disk loses its angular momentum, the mass of the disk gradually drifts towards the black hole and gets accreted. Ultimately the power comes from the gravitational binding energy between the disk and the black hole, as in the standard theory of accretion disk, instead of the rotational energy of the black hole. This suggests that the Blandford-Znajek mechanism may be less efficient in extracting energy from a rotating black hole with a thin disk. The limitations of our simple model and possible improvements deserved for future work are also discussed.Comment: 16 pages, 4 figures. Accepted for publication in Physical Review

New homogeneous iron abundances of double-mode Cepheids from high-resolution echelle spectroscopy

Aims: We define the relationship between the double-mode pulsation of Cepheids and metallicity in a more accurate way, determine the empirical metallicities of double-mode Cepheids from homogeneous, high-resolution spectroscopic data, and study of the period-ratio -- metallicity dependence. Methods: The high S/N echelle spectra obtained with the FEROS spectrograph were analyzed using a self-developed IRAF script, and the iron abundances were determined by comparing with synthetic spectra assuming LTE. Results: Accurate [Fe/H] values of 17 galactic beat Cepheids were determined. All these stars have solar or slightly subsolar metallicity. Their period ratio P1/P0 shows strong correlation with their derived [Fe/H] values. The corresponding period ratio -- metallicity relation has been evaluated.Comment: 10 pages, 7 figures, accepted in A&

Warped accretion discs and the long periods in X-ray binaries

Precessing accretion discs have long been suggested as explanations for the long periods observed in a variety of X-ray binaries, most notably Her X-1/HZ Her. We show that an instability of the disc's response to the radiation reaction force from the illumination by the central source can cause the disc to tilt out of the orbital plane and precess in something like the required manner. The rate of precession and disc tilt obtained for realistic values of system parameters compare favourably with the known body of data on X-ray binaries with long periods. We explore other possible types of behaviour than steadily precessing discs that might be observable in systems with somewhat different parameters. At high luminosities, the inner disc tilts through more than 90 degrees, i.e. it rotates counter to the usual direction, which may explain the torque reversals in systems such as 4U 1626-67.Comment: submitted to MNRAS, 17-Dec-97, revised submit 2-Nov-98. 15 pages LaTeX, 11 postscript figures in-tex

Bi-directional association between depression and HF: An electronic health records-based cohort study.

To determine whether a bi-directional relationship exists between depression and HF within a single population of individuals receiving primary care services, using longitudinal electronic health records (EHRs). This retrospective cohort study utilized EHRs for adults who received primary care services within a large healthcare system in 2006. Validated EHR-based algorithms identified 10,649 people with depression (depression cohort) and 5,911 people with HF (HF cohort) between January 1, 2006 and December 31, 2018. Each person with depression or HF was matched 1:1 with an unaffected referent on age, sex, and outpatient service use. Each cohort (with their matched referents) was followed up electronically to identify newly diagnosed HF (in the depression cohort) and depression (in the HF cohort) that occurred after the index diagnosis of depression or HF, respectively. The risks of these outcomes were compared (vs. referents) using marginal Cox proportional hazard models adjusted for 16 comorbid chronic conditions. 2,024 occurrences of newly diagnosed HF were observed in the depression cohort and 944 occurrences of newly diagnosed depression were observed in the HF cohort over approximately 4-6 years of follow-up. People with depression had significantly increased risk for developing newly diagnosed HF (HR 2.08, 95% CI 1.89-2.28) and people with HF had a significantly increased risk of newly diagnosed depression (HR 1.34, 95% CI 1.17-1.54) after adjusting for all 16 comorbid chronic conditions. These results provide evidence of a bi-directional relationship between depression and HF independently of age, sex, and multimorbidity from chronic illnesses

Particle Motion and Electromagnetic Fields of Rotating Compact Gravitating Objects with Gravitomagnetic Charge

The exact solution for the electromagnetic field occuring when the Kerr-Taub-NUT compact object is immersed (i) in an originally uniform magnetic field aligned along the axis of axial symmetry (ii) in dipolar magnetic field generated by current loop has been investigated. Effective potential of motion of charged test particle around Kerr-Taub-NUT gravitational source immersed in magnetic field with different values of external magnetic field and NUT parameter has been also investigated. In both cases presence of NUT parameter and magnetic field shifts stable circular orbits in the direction of the central gravitating object. Finally we find analytical solutions of Maxwell equations in the external background spacetime of a slowly rotating magnetized NUT star. The star is considered isolated and in vacuum, with monopolar configuration model for the stellar magnetic field.Comment: 18 pages, 6 figures, new results in section 2 added, section 3 is revised, 3 references are adde

Multimorbidity in bipolar disorder and under-treatment of cardiovascular disease: a cross sectional study

Background: Individuals with serious mental disorders experience poor physical health, especially increased rates of cardiometabolic morbidity and premature morbidity. Recent evidence suggests that individuals with schizophrenia have numerous comorbid physical conditions which may be under-recorded and under-treated but to date very few studies have explored this issue for bipolar disorder. Methods:We conducted a cross-sectional analysis of a dataset of 1,751,841 registered patients within 314 primary-care practices in Scotland, U.K. Bipolar disorder was identified using Read Codes recorded within electronic medical records. Data on 32 common chronic physical conditions were also assessed. Potential prescribing inequalities were evaluated by analyzing prescribing data for coronary heart disease (CHD) and hypertension. Results: Compared to controls, individuals with bipolar disorder were significantly less likely to have no recorded physical conditions (OR 0.59, 95% CI 0.54-0.63) and significantly more likely to have one physical condition (OR 1.27, 95% CI 1.16-1.39), two physical conditions (OR 1.45, 95% CI 1.30-1.62) and three or more physical conditions (OR 1.44, 95% CI 1.30-1.64). People with bipolar disorder also had higher rates of thyroid disorders, chronic kidney disease, chronic pain, chronic obstructive airways disease and diabetes but, surprisingly, lower recorded rates of hypertension and atrial fibrillation. People with bipolar disorder and comorbid CHD or hypertension were significantly more likely to be prescribed no antihypertensive or cholesterol-lowering medications compared to controls, and bipolar individuals with CHD or hypertension were significantly less likely to be on 2 or more antihypertensive agents. Conclusions: Individuals with bipolar disorder are similar to individuals with schizophrenia in having a wide range of comorbid and multiple physical health conditions. They are also less likely than controls to have a primary-care record of cardiovascular conditions such as hypertension and atrial fibrillation. Those with a recorded diagnosis of CHD or hypertension were less likely to be treated with cardiovascular medications and were treated less intensively. This study highlights the high physical healthcare needs of people with bipolar disorder, and provides evidence for a systematic under-recognition and under-treatment of cardiovascular disease in this group