Releasing dye encapsulated in proteinaceous microspheres on conductive fabrics by electric current

The current paper reports on the relase properties of conductive fabrics coated with proteinaceous microspheres containing a dye. The release of the dye was achieved by passing an electric current through the fabric. The conductivity of the polyester fibers resulted from nanosilver (Ag NPs) coated on the surface of these fibers. Both types of coatings (nanosilver coating and the coating of the proteinaceous microspheres) were performed using high-intensity ultrasonic waves. Two different types of dyes, hydrophilic RBBR (Remazol Brilliant Blue R) and hydrophobic ORO (Oil Red O), were encapsulated inside the microspheres (attached to the surface of polyester) and then released by applying an electric current. The Proteinaceous Microsphere (PM)-coated conductive fabrics could be used in medicine for drug release. The encapsulated dye can be replaced with a drug that could be released from the surface of fabrics by applying a low voltage

Hierarchically Porous Gd3+-Doped CeO2 Nanostructures for the Remarkable Enhancement of Optical and Magnetic Properties

Rare earth ion-doped CeO2 has attracted more and more attention because of its special electrical, optical, magnetic, or catalytic properties. In this paper, a facile electrochemical deposition route was reported for the direct growth of the porous Gd-doped CeO2. The formation process of Gd-doped CeO2 composites was investigated. The obtained deposits were characterized by SEM, EDS, XRD, and XPS. The porous Gd3+- doped CeO2 (10 at% Gd) displays a typical type I adsorption isotherm and yields a large specific surface area of 135 m2/g. As Gd3+ ions were doped into CeO2 lattice, the absorption spectrum of Gd3+-doped CeO2 nanocrystals exhibited a red shift compared with porous CeO2 nanocrystals and bulk CeO2, and the luminescence of Gd3+-doped CeO2 deposits was remarkably enhanced due to the presence of more oxygen vacancies. In addition, the strong magnetic properties of Gd-doped CeO2 (10 at% Gd) were observed, which may be caused by Gd3+ ions or more oxygen defects in deposits. In addition, the catalytic activity of porous Gd-doped CeO2 toward CO oxidation was studied

Detection of human neutrophil elastase (HNE) on wound dressings as marker of inflammation

Chronic wound fluids have elevated concentration of human neutrophil elastase (HNE) which can be used as inflammation/infection marker. Our goal is to develop functional materials for fast diagnosis of wound inflammation/infection by using HNE as a specific marker. For that, fluorogenic peptides with a HNE-specific cleavage sequence were incorporated into traditional textile dressings, to allow real-time detection of the wound status. Two different fluorogenic approaches were studied in terms of intensity of the signal generated upon HNE addition: a fluorophore 7-amino-4-trifluormethylcoumarin (AFC) conjugated to a HNE-specific peptide and two fluorophore/quencher pairs (FAM/Dabcyl and EDANS/Dabcyl) coupled to a similar peptide as a Förster resonance energy transfer (FRET) strategy. Also, two immobilization methods were tested: sonochemistry immobilization onto a cotton bandage and glutaraldehyde (GTA)-assisted chemical crosslinking onto a polyamide dressing. The immobilized fluorogenic AFC peptide showed an intense fluorescence emission in the presence of HNE. HNE also induced an enhanced fluorescent signal with the EDANS/Dabcyl FRET peptide which showed to be a more sensitive and effective strategy than the AFC peptide. However, its chemical immobilization onto the polyamide dressing greatly decreased its detection, mainly due to the more difficult access of the enzyme to the cleavage sequence of the immobilized peptide. After optimization of the in situ immobilization, it will be possible to use these fluorescence-functionalized dressings for an effective and specific monitoring of chronic wounds by simply using a portable ultraviolet (UV) light source. We envision that the development of this point-of-care medical device for wound control will have a great impact on patients life quality and reduction of costs on health care system.This study was funded by the European project InFact-Functional materials for fast diagnosis of wound infection (FP7-NMP-2013-SME-7-grant agreement no. 604278). The work done at Centre of Biological Engineering (CEB) was also supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/04469/2013 unit, COMPETE 2020 (POCI-01-0145-FEDER-006684) and BioTecNorte operation (NORTE-01-0145-FEDER-000004) funded by European Regional Development Fund under the scope of Norte 2020-Programa Operacional Regional do Norte

Sonochemistry as a tool for preparation of porous metal oxides

Abstract: The porous metal oxides are an important class of materials, because the surface area/volume ratio of a material is increased by many fold, making them very useful in surface-related applications. The mesoporous materials were discovered in the 1990s, and since then they have been excellent candidates for materials science research. These mesoporous materials are prepared by hydrolyzing the inorganic precursor (usually metal alkoxide) in an acid, basic, or neutral medium in the presence of an organic structure-directing agent, the surfactant, in a conventional method. Recently, we have demonstrated that the sonochemical technique can be employed for the synthesis of mesoporous metal oxides. The sonochemical method reduced the time period required for such synthesis by many fold, and also produced more stable structures. We got excellent results with silica, titania, yittria-stabilized zirconia (YSZ), and Fe 2 O 3 . We also used an inorganic precursor other than an alkoxide for the preparation of mesoporous metal oxides. In this article, we present some of the recent results on this topic. ULTRASOUND + CHEMISTRY = SONOCHEMISTRY Power ultrasound influences chemical reactivity through an effect known as "cavitation". Cavitation occurs by applying high-intensity ultrasound to liquids, resulting in the superimposition of sinusoidal pressure on the steady ambient pressure. Sound is transmitted through a fluid as a wave consisting of alternating compression and rarefaction cycles. In the phenomenon called cavitation, the microbubbles formed during the rarefaction cycle of the acoustic wave undergo violent collapse during the compression cycle of the wave. During the compression cycle, the bubble's content is estimated to be heated to 5000 K, and the implosion of the cavitation bubble also produced high-energy shock waves with pressures of several thousand atmosphere

Sonochemically prepared high dispersed Ru/Tio2 mesoporous catalyst for partial oxidation of methane to syngas

Highly dispersed Ru nanoparticles on mesoporous TiO2 have been synthesized by a one-step ultrasound assisted polyol redn. procedure. The catalysts have been characterized by XRD, TEM and HR-TEM, EDX, BET and TPR methods. It has been demonstrated that the sonochem. method reduces the Ru+3 ions creating a narrow size distribution of metallic nanoparticles deposited on the mesoporous support without damaging its pore structure. The nanoparticles of Ru are highly dispersed and stable because of their incorporation into the mesopores, and the strong metal-support interaction. The catalytic properties of Ru/TiO2(MSP) have been tested in the partial oxidn. of methane, and high activity and selectivity towards CO and H2 have been demonstrated

Sonochemical stabilization of ultrafine colloidal biocompatible magnetite nanoparticles using amino acid, L-arginine, for possible bio applications

Materials obtained by the synergistic combination of nanotechnology and biomedicine are an important source of drug delivery and other health care related applications The anchoring of amino acids onto the surface of nano-sized magnetite is one such example. Herein, we report on the binding of a semi-essential amino acid, L-arginine, onto the surface of nano magnetite, creating a stable aqueous suspension by an in situ one-step method using sonochemical synthesis An ex situ two-step process was also attempted, but was soon discarded owing to the relative short duration of the suspension attributed to increase in particle size and lower extent of binding The initial concentration of the amino acid was found to play an important role in controlling the particle size and also the binding motif Lower concentrations of arginine were found to favor the formation of elongated tubular structures, while at higher concentrations, the elongated structures were less prominent and arginine was found to be adsorbed onto the surface of the magnetite This surface-functionalized nanomagnetite with amino acids could become a promising vehicle for drug delivery. (C) 200