Flavour in supersymmetry: horizontal symmetries or wave function renormalisation

We compare theoretical and experimental predictions of two main classes of models addressing fermion mass hierarchies and flavour changing neutral currents (FCNC) effects in supersymmetry: Froggatt-Nielsen (FN) U(1) gauged flavour models and Nelson-Strassler/extra dimensional models with hierarchical wave functions for the families. We show that whereas the two lead to identical predictions in the fermion mass matrices, the second class generates a stronger suppression of FCNC effects. We prove that, whereas at first sight the FN setup is more constrained due to anomaly cancelation conditions, imposing unification of gauge couplings in the second setup generates conditions which precisely match the mixed anomaly constraints in the FN setup. Finally, we provide an economical extra dimensional realisation of the hierarchical wave functions scenario in which the leptonic FCNC can be efficiently suppressed due to the strong coupling (CFT) origin of the electron mass.Comment: 23 page

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors.

The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/bph.15538. G protein-coupled receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2021, and supersedes data presented in the 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate

Weakly nonlinear analysis of Benard-Marangoni instability in viscoelastic fluids

The coupled thermogravitational and thermocapillary instability in a thin fluid layer of a viscoelastic medium heated from below is investigated. A linear and a weakly nonlinear analysis are successively presented. The viscoelastic medium is modelled by means of a general rheological model including the lower convected, the upper convected, and the co-rotational Jeffreys models as particular cases. in comparison with previous analyses, two new dimensionless numbers are introduced, namely the so-called gravitational and rate of heating numbers instead of the classical Rayleigh and Marangoni numbers. The critical values for the temperature gradient, wave number and oscillation frequencies corresponding to the onset of convection are determined from a linear approach. After motion has set in, particular patterns are predicted taking the form of either rolls, or hexagon, or squares. By means of a nonlinear technique, restricted to steady situations, it is determined under which specific conditions one pattern is preferred. The influence of the constitutive equation, the Prandtl and the Blot numbers is examined and discussed in details. (C) 2000 Elsevier Science B.V. All rights reserved

9. Laboratoire de chimie à la Sorbonne

Troost L., Riban J., de Clermont Ph., Parmentier F. 9. Laboratoire de chimie à la Sorbonne. In: Rapport sur l'École pratique des hautes études, 1882-1883. 1882. pp. 39-46

9. Laboratoire de chimie à la Sorbonne

Troost L., Riban J., de Clermont Ph., Parmentier F. 9. Laboratoire de chimie à la Sorbonne. In: Rapport sur l'École pratique des hautes études, 1882-1883. 1882. pp. 39-46

X-ray imaging plate performance investigation based on a Monte Carlo simulation tool

International audienceComputed radiography (CR) based on imaging plate (IP) technology represents a potential replacement technique for traditional film-based industrial radiography. For investigating the IP performance especially at high energies, a Monte Carlo simulation tool based on PENELOPE has been developed. This tool tracks separately direct and secondary radiations, and monitors the behavior of different particles. The simulation output provides 3D distribution of deposited energy in IP and evaluation of radiation spectrum propagation allowing us to visualize the behavior of different particles and the influence of different elements. A detailed analysis, on the spectral and spatial responses of IP at different energies up to MeV, has been performed

Diffractométrie de poudres d'alliages de tungstène nanostructurées par mécanosynthèse

High energy ball milling carried out in a planetary ball mill is generally used to alloy elementary powders and to obtain nanostructures. The latter advantages urge us to elaborate pure tungsten or blends of tungsten and yttria powders by means of this process. The obtained powders are then sintered in order to achieve creepproof materials at high temperature. The ball-to-powder ratio is constant during the experiments. The effects of different milling parameters (number of balls: 2, 16, 92 ; milling time: 5mn, 20mn, 40mn, 80mn, rotational speed: 200 or 300 or 400 rpm, nature of the milling system: stainless steel or tungsten carbide system) and of the composition of blends (volumetric content of second phase) are examined. The results concern nanocrystals in the powder particles, the strain level of powder particles, the formation of alloys and the oxide particles dispersion. The difficulties and advantages of the characterization techniques are developed. The consequences of structural changes are outlined and the mechanisms of the alloy evolution discussed.Le broyage à haute énergie effectué dans un broyeur planétaire de type Fritsch Pulvérisette 6 permet à la fois de mettre en alliage des poudres élémentaires mais aussi d'obtenir une nanostructure. Ces avantages privilégient l'emploi de cette technique pour l'élaboration de poudres à partir de particules de tungstène pur, ou de mélanges de particules de tungstène et d'oxyde d'yttrium. Les poudres obtenues sont ensuite frittées dans le but d'obtenir des matériaux à forte résistance au fluage à haute température. Le rapport entre la masse des billes et celle de la poudre déformée, a été maintenue constante au cours des expériences. Les effets des différents paramètres de broyage (nombre de billes : 2, 16, 92 ; durée de broyage : 5 mn, 20 mn, 40 mn, 80 mn ; vitesse de broyage : 200, 300, 400 tours par minute ; nature du système de broyage système en acier inoxydable ou en carbure de tungstène) et de la composition du mélange d'origine (teneur volumique de seconde phase) sont examinés. Les résultats concernent les nanocristaux au sein des particules de poudre, le taux de déformation des particules de poudre, la mise en alliage mécanique ou la distribution géométrique des particules d'oxyde. Les difficultés et avantages respectifs des différentes techniques d'analyse sont dégagés. Les conséquences pratiques des modifications structurales sont esquissées et les mécanismes de l'évolution de l'alliage soumis aux impacts discutés

Cholestéatome du haut appareil urinaire: traitement endoscopique

We report here on a case of cholesteatoma of the upper urinary tract. This rare, but recurrent disease was managed successfully by means of repeated endourological treatment. Diagnosis was confirmed by histological examination of samples obtained by percutaneous extraction