45 research outputs found
The expansion field: The value of H_0
Any calibration of the present value of the Hubble constant requires
recession velocities and distances of galaxies. While the conversion of
observed velocities into true recession velocities has only a small effect on
the result, the derivation of unbiased distances which rest on a solid zero
point and cover a useful range of about 4-30 Mpc is crucial. A list of 279 such
galaxy distances within v<2000 km/s is given which are derived from the tip of
the red-giant branch (TRGB), from Cepheids, and from supernovae of type Ia (SNe
Ia). Their random errors are not more than 0.15 mag as shown by
intercomparison. They trace a linear expansion field within narrow margins from
v=250 to at least 2000 km/s. Additional 62 distant SNe Ia confirm the linearity
to at least 20,000 km/s. The dispersion about the Hubble line is dominated by
random peculiar velocities, amounting locally to <100 km/s but increasing
outwards. Due to the linearity of the expansion field the Hubble constant H_0
can be found at any distance >4.5 Mpc. RR Lyr star-calibrated TRGB distances of
78 galaxies above this limit give H_0=63.0+/-1.6 at an effective distance of 6
Mpc. They compensate the effect of peculiar motions by their large number.
Support for this result comes from 28 independently calibrated Cepheids that
give H_0=63.4+/-1.7 at 15 Mpc. This agrees also with the large-scale value of
H_0=61.2+/-0.5 from the distant, Cepheid-calibrated SNe Ia. A mean value of
H_0=62.3+/-1.3 is adopted. Because the value depends on two independent zero
points of the distance scale its systematic error is estimated to be 6%.
Typical errors of H_0 come from the use of a universal, yet unjustified P-L
relation of Cepheids, the neglect of selection bias in magnitude-limited
samples, or they are inherent to the adopted models.Comment: 44 pages, 4 figures, 6 tables, accepted for publication in the
Astronony and Astrophysics Review 15
Supernova remnants: the X-ray perspective
Supernova remnants are beautiful astronomical objects that are also of high
scientific interest, because they provide insights into supernova explosion
mechanisms, and because they are the likely sources of Galactic cosmic rays.
X-ray observations are an important means to study these objects.And in
particular the advances made in X-ray imaging spectroscopy over the last two
decades has greatly increased our knowledge about supernova remnants. It has
made it possible to map the products of fresh nucleosynthesis, and resulted in
the identification of regions near shock fronts that emit X-ray synchrotron
radiation.
In this text all the relevant aspects of X-ray emission from supernova
remnants are reviewed and put into the context of supernova explosion
properties and the physics and evolution of supernova remnants. The first half
of this review has a more tutorial style and discusses the basics of supernova
remnant physics and thermal and non-thermal X-ray emission. The second half
offers a review of the recent advances.The topics addressed there are core
collapse and thermonuclear supernova remnants, SN 1987A, mature supernova
remnants, mixed-morphology remnants, including a discussion of the recent
finding of overionization in some of them, and finally X-ray synchrotron
radiation and its consequences for particle acceleration and magnetic fields.Comment: Published in Astronomy and Astrophysics Reviews. This version has 2
column-layout. 78 pages, 42 figures. This replaced version has some minor
language edits and several references have been correcte
Social deprivation as a risk factor for late presentation of proliferative diabetic retinopathy
Mark Lane,1,* Priscilla A Mathewson,1,* Hannah E Sharma,1 Helen Palmer,1 Peter Shah,1–3 Peter Nightingale,1,4,5 Marie D Tsaloumas,1 Alastair K Denniston1,61Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK; 2NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK; 3Centre for Health and Social Care Improvement, School of Health and Wellbeing, University of Wolverhampton, Wolverhampton, UK; 4Dept of Statistics, Wellcome Trust Clinical Research Facility, Birmingham, UK; 5School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, 6Centre for Translational Inflammation Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK*These authors are joint first authorsPurpose: The aim of this study was to determine whether social deprivation is a risk factor for late presentation of patients with proliferative diabetic retinopathy and whether it affects their access to urgent laser treatment.Methods: Using a 2:1 case: control design, 102 patients referred to a UK teaching hospital as part of the UK Diabetic Retinopathy National Screening Programme were identified for the period between 1 June 2010 to 1 June 2013. Social deprivation was scored using the Index of Multiple Deprivation 2010. Additional variables considered included age, duration of disease, ethnicity, and HbA1c at time of referral.Results: The cases comprised 34 patients referred with proliferative (grade R3) retinopathy with a control group of 68 patients with lower retinopathy grades; two control patients were excluded due to incomplete data. On univariate analysis, R3 retinopathy was associated with higher social deprivation (P<0.001, Mann–Whitney U-test), and with higher HbA1c (11.5% vs 8.4%; P<0.001, Mann–Whitney U-test). Forward stepwise multivariable analysis showed that the association of R3 retinopathy with deprivation was significant even after adjusting for HbA1c (P=0.016). On univariate analysis South Asian ethnicity was also identified as being a risk factor for presentation with R3 retinopathy, but this was no longer significant when HbA1c was adjusted for in a forward stepwise logistic regression analysis.Conclusion: In our cohort social deprivation appears to be associated with late presentation of proliferative diabetic retinopathy. Our study supports the need to target these groups to reduce preventable blindness and to identify strategies which overcome barriers to care.Keywords: social deprivation, index of multiple deprivation, diabetes, proliferative diabetic retinopath