2,487 research outputs found

    An Intelligent System for Effective Mobile Application Advertising

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    [[abstract]]Due to the advance of big data and increasing availability of smartphones equipped with various sensors and networking capability, it provides new opportunities for innovating mobile application advertising services. Unlike Web, where cookies for identifying users store in web browsers, there is a challenge for mobile apps to track users so acquiring sufficient data for training from ideal sampling distribution is computationally and economically expensive. Thus, a massive-scale intelligent system for targeted mobile app display advertising is developed to capture data for the learning task and transfer extracted knowledge back to the target task. The proposed system is evaluated by real world data and deployed to an advertising agency, illustrating the practicability and applicability.[[sponsorship]]Taiwanese Association for Artificial Intelligence (TAAI)[[conferencetype]]國際[[conferencedate]]20131206~20131208[[booktype]]紙本[[iscallforpapers]]Y[[conferencelocation]]Taipei, Taiwa

    Human T lymphocyte activation kinetics for identifying and targeting alloreactive T cells

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    Immobilization of single strand DNA on solid substrate

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    Thin films based on Layer-by-Layer (LbL) self assembled technique are useful for immobilization of DNA onto solid support. This communication reports the immobilization of DNA onto a solid support by electrostatic interaction with a polycation Poly (allylamine hydrochloride) (PAH). UV-Vis absorption and steady state fluorescence spectroscopic studies exhibit the characteristics of DNA organized in LbL films. The most significant observation is that single strand DNA are immobilized on the PAH backbone of LbL films when the films are fabricated above the melting temperature of DNA. DNA immobilized in this way on LbL films remains as such when the temperature is restored at room temperature and the organization remains unaffected even after several days. UV-Vis absorption spectroscopic studies confirm this finding.Comment: Eight pages, five figure

    Extended States in a One-dimensional Generalized Dimer Model

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    The transmission coefficient for a one dimensional system is given in terms of Chebyshev polynomials using the tight-binding model. This result is applied to a system composed of two impurities located between NN sites of a host lattice. It is found that the system has extended states for several values of the energy. Analytical expressions are given for the impurity site energy in terms of the electron's energy. The number of resonant states grows like the number of host sites between the impurities. This property makes the system interesting since it is a simple task to design a configuration with resonant energy very close to the Fermi level EFE_F.Comment: 4 pages, 3 figure

    Maxwell Chern Simons Theory in a Geometric Representation

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    We quantize the Maxwell Chern Simons theory in a geometric representation that generalizes the Abelian Loop Representation of Maxwell theory. We find that in the physical sector, the model can be seen as the theory of a massles scalar field with a topological interaction that enforces the wave functional to be multivalued. This feature allows to relate the Maxwell Chern Simons theory with the quantum mechanics of particles interacting through a Chern Simons fieldComment: 12 pages, LaTe

    Distribution of nerve fibers and nerve-immune cell association in mouse spleen revealed by immunofluorescent staining

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    The central nervous system regulates the immune system through the secretion of hormones from the pituitary gland and other endocrine organs, while the peripheral nervous system (PNS) communicates with the immune system through local nerve-immune cell interactions, including sympathetic/parasympathetic (efferent) and sensory (afferent) innervation to lymphoid tissue/organs. However, the precise mechanisms of this bi-directional crosstalk of the PNS and immune system remain mysterious. To study this kind of bi-directional crosstalk, we performed immunofluorescent staining of neurofilament and confocal microscopy to reveal the distribution of nerve fibers and nerve-immune cell associations inside mouse spleen. Our study demonstrates (i) extensive nerve fibers in all splenic compartments including the splenic nodules, periarteriolar lymphoid sheath, marginal zones, trabeculae, and red pulp; (ii) close associations of nerve fibers with blood vessels (including central arteries, marginal sinuses, penicillar arterioles, and splenic sinuses); (iii) close associations of nerve fibers with various subsets of dendritic cells, macrophages (Mac1+ and F4/80+), and lymphocytes (B cells, T helper cells, and cytotoxic T cells). Our data concerning the extensive splenic innervation and nerve-immune cell communication will enrich our knowledge of the mechanisms through which the PNS affects the cellular- and humoral-mediated immune responses in healthy and infectious/non-infectious states

    Theory of nonlinear Landau-Zener tunneling

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    A nonlinear Landau-Zener model was proposed recently to describe, among a number of applications, the nonadiabatic transition of a Bose-Einstein condensate between Bloch bands. Numerical analysis revealed a striking phenomenon that tunneling occurs even in the adiabatic limit as the nonlinear parameter CC is above a critical value equal to the gap VV of avoided crossing of the two levels. In this paper, we present analytical results that give quantitative account of the breakdown of adiabaticity by mapping this quantum nonlinear model into a classical Josephson Hamiltonian. In the critical region, we find a power-law scaling of the nonadiabatic transition probability as a function of C/V−1C/V-1 and α\alpha , the crossing rate of the energy levels. In the subcritical regime, the transition probability still follows an exponential law but with the exponent changed by the nonlinear effect. For C/V>>1C/V>>1, we find a near unit probability for the transition between the adiabatic levels for all values of the crossing rate.Comment: 9 figure

    Supergravity Solutions for BI Dyons

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    We construct partially localized supergravity counterpart solutions to the 1/2 supersymmetric non-threshold and the 1/4 supersymmetric threshold bound state BI dyons in the D3-brane Dirac-Born-Infeld theory. Such supergravity solutions have all the parameters of the BI dyons. By applying the IIA/IIB T-duality transformations to these supergravity solutions, we obtain the supergravity counterpart solutions to 1/2 and 1/4 supersymmetric BIons carrying electric and magnetic charges of the worldvolume U(1) gauge field in the Dirac-Born-Infeld theory in other dimensions.Comment: 17 pages, REVTeX, revised version to appear in Phys. Rev.

    Impact of cyclic bending on coronary hemodynamics

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    It remains unknown that the degree of bias in computational fluid dynamics results without considering coronary cyclic bending. This study aims to investigate the influence of different rates of coronary cyclic bending on coronary hemodynamics. To model coronary bending, a multi-ring-controlled fluid–structural interaction model was designed. A coronary artery was simulated with various cyclic bending rates (0.5, 0.75 and 1 s, corresponding to heart rates of 120, 80 and 60 bpm) and compared against a stable model. The simulated results show that the hemodynamic parameters of vortex Q-criterion, temporal wall shear stress (WSS), time-averaged WSS (TaWSS) and oscillatory shear index (OSI) were sensitive to the changes in cyclic rate. A higher heart rate resulted in higher magnitude and larger variance in the hemodynamic parameters. Whereas, the values and distributions of flow velocity and relative residence time (RRT) did not show significant differences between different bending periods. This study suggests that a stable coronary model is not sufficient to represent the hemodynamics in a bending coronary artery. Different heart rate conditions were found to have significant impact on the hemodynamic parameters. Thus, cyclic bending should be considered to mimic the realistic hemodynamics in future patient-specific coronary hemodynamics studies
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