34 research outputs found

    Signal transduction via protein-coupled receptors: Ternary complexes as secondary proton pumps and GTP synthases.

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    The role of arginine in the binding of LTD4 antagonists to Cys LT1 receptors of guinea pig ileum.

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    Using the chemical masking agent phenylglyoxal, we have selectively blocked the arginine residues in leukotriene cysL

    Polymer foam comprising a polymer and nanoparticles, and nanoparticles for the manufacture of such foam.

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    A polymer foam is produced comprising a polymer and nanoparticles having a maximum dimensionof 750 nm, which foam has cells with an average cell size of at most 1 µm and a cell density of at least 1012 cells/ml, wherein polymeric grafts have been attached to the nanoparticles. The nanoparticles may be particles with a solid core or porous hollow core-shell particles. The foam can be manufactured by dispersing the nanoparticles in a polymer to yield a dispersion; by adding a blowing agent to the dispersion to obtain an expandable mixture; and by foaming the expandable mixture to obtain the polymer foam

    Does the tenary complex act as a secondary proton pump and a GTP synthase?

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    It has been suggested that G protein-coupled receptors can act as proton transporters, with the activated G protein-coupled receptor transporting
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