ASD Symptom Severity in Adolescence of Individuals Diagnosed with PDD-NOS in Childhood

The current 7-year follow-up study investigated: (1) the stability of ASD severity, and (2) associations of ASD severity in adolescence with (a) childhood and concurrent psychiatric comorbidity, and (b) concurrent societal functioning. The Autism Diagnostic Observation Schedule (ADOS) and the Diagnostic Interview Schedule for Children were administered in childhood (ages 6–12) and in adolescence (ages 12–20) to 72 individuals with a pervasive developmental disorder-not otherwise specified (PDD-NOS). ADOS calibrated severity scores showed a large stability (r = .51). Psychiatric comorbidity in childhood and adolescence were not associated wit

Dynamic nuclear polarization and spin-diffusion in non-conducting solids

There has been much renewed interest in dynamic nuclear polarization (DNP), particularly in the context of solid state biomolecular NMR and more recently dissolution DNP techniques for liquids. This paper reviews the role of spin diffusion in polarizing nuclear spins and discusses the role of the spin diffusion barrier, before going on to discuss some recent results.Comment: submitted to Applied Magnetic Resonance. The article should appear in a special issue that is being published in connection with the DNP Symposium help in Nottingham in August 200

Nuclear magnetic ordening in fluorene

The present paper considers the possibility to obtain a magnetic ordering of the proton spins in molecular crystals of fluorene using dynamic nuclear polarization (DNP) followed by adibatic demagnetization in the rotating frame (ADRF). It is found that such an ordering is most easily reached for $T < 0$ and B $_0$ $\parallel$ $c$-axis. Then a polarization of only 26% needs to be reached by DNP in order to obtain a ferromagnetic ordering. The importance of fluorene lies in the possibility to use photoexcited triplet states for DNP. Then, during and after the ADRF the sample is free of paramagnetic centres and a cleaner study of the ordering can be made.Ce travail discute la possibilité d'obtenir de l'ordre magnétique nucléaire dans des cristaux moléculaires de fluorene par polarisation dynamique nucléaire (DNP) suivi par desaimantation adiabatique nucléaire dans le référentiel tournant (ADRF). On trouve que cet ordre est obtenu de la façon la plus facile orientant B $_0$ $\parallel$ à l'axe $c$ et choisissant $T < 0$. Alors une polarisation nucléaire de 26% suffit pour obtenir un ordre ferromagnétique. L'importance du fluorene est donnée par la possibilité d'utiliser des triplets photoexcités pour la DNP. Alors, pendant et après la ADRF l'échantillon ne contient pas des centres paramagnétiques et l'étude de l'ordre magnétique nucléaire est plus pure