33 research outputs found
Influence of 2-Mercaptoethanol Treatment on Opsonizing Activity of Human and Rabbit 7 S Antibodies
Unusual manifestations of type II cryoglobulinaemia associated with Waldenström's macroglobulinaemia
Cryoglobulinaemia in association with Waldenström's macroglobulinaemia is relatively common, ranging from 8% to 18% of cases; however, < 5% have symptoms or complications. We describe a patient with a history of cutaneous, peritoneal, and fallopian tube vasculitis related to type II cryoglobulinaemia associated with Waldenström's macroglobulinaemia. Cytotoxic treatment was initiated (cyclophosphamide, vincristine, and prednisone) and had a good initial response. However, after the third course of chemotherapy, the patient presented with septic shock and died. Even though cryoglobulinaemia is a model of systemic vasculitis, peritoneal and fallopian tube vasculitis associated with type II cryoglobulinemia has not been described previously. Key Words: cryoglobulinaemia • Waldenström's macroglobulinaemia • peritoneum • fallopian tub