789 research outputs found

    High-speed Photometric Observations of ZZ Ceti White Dwarf Candidates

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    We present high-speed photometric observations of ZZ Ceti white dwarf candidates drawn from the spectroscopic survey of bright DA stars from the Villanova White Dwarf Catalog by Gianninas et al., and from the recent spectroscopic survey of white dwarfs within 40 parsecs of the Sun by Limoges et al. We report the discovery of six new ZZ Ceti pulsators from these surveys, and several photometrically constant DA white dwarfs, which we then use to refine the location of the ZZ Ceti instability strip.Comment: 4 pages, 1 table, 2 figures, to appear in "19th European White Dwarf Workshop" in the ASP Conference Serie

    Dendritic Cells Cause Bone Lesions in a New Mouse Model of Histiocytosis.

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    Langerhans cell histiocytosis (LCH) is a rare disease caused by the clonal accumulation of dendritic Langerhans cells, which is often accompanied by osteolytic lesions. It has been reported that osteoclast-like cells play a major role in the pathogenic bone destruction seen in patients with LCH and these cells are postulated to originate from the fusion of DCs. However, due to the lack of reliable animal models the pathogenesis of LCH is still poorly understood. In this study, we have established a mouse model of histiocytosis- recapitulating human disease for osteolytic lesions seen in LCH patients. At 12 weeks after birth, severe bone lesions were observed in our multisystem histiocytosis (Mushi) model, when CD8α conventional dendritic cells (DCs) are transformed (MuTuDC) and accumulate. Most importantly, our study demonstrates that bone loss in LCH can be accounted for the transdifferentiation of MuTuDCs into functional osteoclasts both in vivo and in vitro. Moreover, we have shown that injected MuTuDCs reverse the osteopetrotic phenotype of oc/oc mice in vivo. In conclusion, our results support a crucial role of DCs in bone lesions in histiocytosis patients. Furthermore, our new model of LCH based on adoptive transfer of MuTuDC lines, leading to bone lesions within 1-2 weeks, will be an important tool for investigating the pathophysiology of this disease and ultimately for evaluating the potential of anti-resorptive drugs for the treatment of bone lesions

    Antiperiodic dynamical 6-vertex model I: Complete spectrum by SOV, matrix elements of the identity on separate states and connections to the periodic 8-vertex model

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    The spin-1/2 highest weight representations of the dynamical 6-vertex and the standard 8-vertex Yang-Baxter algebra on a finite chain are considered in this paper. For the antiperiodic dynamical 6-vertex transfer matrix defined on chains with an odd number of sites, we adapt the Sklyanin's quantum separation of variable (SOV) method and explicitly construct SOV representations from the original space of representations. We provide the complete characterization of eigenvalues and eigenstates proving also the simplicity of its spectrum. Moreover, we characterize the matrix elements of the identity on separated states by determinant formulae. The matrices entering in these determinants have elements given by sums over the SOV spectrum of the product of the coefficients of separate states. This SOV analysis is not reduced to the case of the elliptic roots of unit and the results here derived define the required setup to extend to the dynamical 6-vertex model the approach recently developed in [1]-[5] to compute the form factors of the local operators in the SOV framework, these results will be presented in a future publication. For the periodic 8-vertex transfer matrix, we prove that its eigenvalues have to satisfy a fixed system of equations. In the case of a chain with an odd number of sites, this system of equations is the same entering in the SOV characterization of the antiperiodic dynamical 6-vertex transfer matrix spectrum. This implies that the set of the periodic 8-vertex eigenvalues is contained in the set of the antiperiodic dynamical 6-vertex eigenvalues. A criterion is introduced to find simultaneous eigenvalues of these two transfer matrices and associate to any of such eigenvalues one nonzero eigenstate of the periodic 8-vertex transfer matrix by using the SOV results. Moreover, a preliminary discussion on the degeneracy of the periodic 8-vertex spectrum is also presented.Comment: 36 pages, main modifications in section 3 and one appendix added, no result modified for the dynamical 6-vertex transfer matrix spectrum and the matrix elements of identity on separate states for chains with an odd number of site

    A comparison of methods for gravitational wave burst searches from LIGO and Virgo

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    The search procedure for burst gravitational waves has been studied using 24 hours of simulated data in a network of three interferometers (Hanford 4-km, Livingston 4-km and Virgo 3-km are the example interferometers). Several methods to detect burst events developed in the LIGO Scientific Collaboration (LSC) and Virgo collaboration have been studied and compared. We have performed coincidence analysis of the triggers obtained in the different interferometers with and without simulated signals added to the data. The benefits of having multiple interferometers of similar sensitivity are demonstrated by comparing the detection performance of the joint coincidence analysis with LSC and Virgo only burst searches. Adding Virgo to the LIGO detector network can increase by 50% the detection efficiency for this search. Another advantage of a joint LIGO-Virgo network is the ability to reconstruct the source sky position. The reconstruction accuracy depends on the timing measurement accuracy of the events in each interferometer, and is displayed in this paper with a fixed source position example.Comment: LIGO-Virgo working group submitted to PR

    Herschel observations of extra-ordinary sources: Detection of Hydrogen Fluoride in absorption towards Orion~KL

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    We report a detection of the fundamental rotational transition of hydrogen fluoride in absorption towards Orion KL using Herschel/HIFI. After the removal of contaminating features associated with common molecules ("weeds"), the HF spectrum shows a P-Cygni profile, with weak redshifted emission and strong blue-shifted absorption, associated with the low-velocity molecular outflow. We derive an estimate of 2.9 x 10^13 cm^-2 for the HF column density responsible for the broad absorption component. Using our best estimate of the H2 column density within the low-velocity molecular outflow, we obtain a lower limit of ~1.6 x 10^-10 for the HF abundance relative to hydrogen nuclei, corresponding to 0.6% of the solar abundance of fluorine. This value is close to that inferred from previous ISO observations of HF J=2--1 absorption towards Sgr B2, but is in sharp contrast to the lower limit of 6 x 10^-9 derived by Neufeld et al. (2010) for cold, foreground clouds on the line of sight towards G10.6-0.4.Comment: 5 pages, 3 figures, paper to be published in the Herschel special issue of A&A letter

    A Cross-correlation method to search for gravitational wave bursts with AURIGA and Virgo

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    We present a method to search for transient GWs using a network of detectors with different spectral and directional sensitivities: the interferometer Virgo and the bar detector AURIGA. The data analysis method is based on the measurements of the correlated energy in the network by means of a weighted cross-correlation. To limit the computational load, this coherent analysis step is performed around time-frequency coincident triggers selected by an excess power event trigger generator tuned at low thresholds. The final selection of GW candidates is performed by a combined cut on the correlated energy and on the significance as measured by the event trigger generator. The method has been tested on one day of data of AURIGA and Virgo during September 2005. The outcomes are compared to the results of a stand-alone time-frequency coincidence search. We discuss the advantages and the limits of this approach, in view of a possible future joint search between AURIGA and one interferometric detector.Comment: 11 pages, 6 figures, submitted to CQG special issue for Amaldi 7 Proceeding

    Astrophysically Triggered Searches for Gravitational Waves: Status and Prospects

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    In gravitational-wave detection, special emphasis is put onto searches that focus on cosmic events detected by other types of astrophysical observatories. The astrophysical triggers, e.g. from gamma-ray and X-ray satellites, optical telescopes and neutrino observatories, provide a trigger time for analyzing gravitational wave data coincident with the event. In certain cases the expected frequency range, source energetics, directional and progenitor information is also available. Beyond allowing the recognition of gravitational waveforms with amplitudes closer to the noise floor of the detector, these triggered searches should also lead to rich science results even before the onset of Advanced LIGO. In this paper we provide a broad review of LIGO's astrophysically triggered searches and the sources they target
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