Postpartum Regression of a Presumed Cavernous Meningioma.

Meningiomas are known to be more common in females than males. They are also known in rare cases to grow in size during pregnancy, which can complicate its management. We describe a 31-year-old Caucasian woman who presented with blurring of her vision and diplopia during the third trimester of her pregnancy. Magnetic resonance imaging (MRI) showed a small left cavernous sinus meningioma. The patient was treated conservatively until her uncomplicated delivery. A postpartum MRI scan showed complete regression of the suspected meningioma. Currently the patient is contemplating a further pregnancy

Direct comparison of boron, phosphorus, and aluminum gettering of iron in crystalline silicon

This paper presents a direct quantitative comparison of the effectiveness of borondiffusion, phosphorus diffusion, and aluminumalloying in removing interstitial iron in crystalline silicon in the context of silicon solar cells. Phosphorus diffusion gettering was effective in removing more than 90% of the interstitial iron across a range of diffusion temperatures, sheet resistances, and iron doses. Even relatively light phosphorus diffusions (145 Ω/□) were found to give very effective gettering, especially when combined with extended low temperature annealing.Aluminumalloying was extremely effective and removed more than 99% of the implanted iron for a range of alloying temperatures and aluminum film thicknesses. In contrast, our experimental results showed that borondiffusion gettering is very sensitive to the deposition conditions and can change from less than 5% of the Fe being gettered to more than 99.9% gettered by changing only the gas flow ratios and the post-oxidation step

Ghost Cosmology: Exact Solutions, Transitions Between Standard Cosmologies and Ghost Dark Energy/Matter Evolution

The recently proposed infrared modification of gravity through the introduction of a ghost scalar field results in a number of interesting cosmological and phenomenological implications. In this paper, we derive the exact cosmological solutions for a number of scenarios where at late stages, the ghost behaves like dark matter, or dark energy. The full solutions give valuable information about the non-linear regime beyond the asymptotic first order analysis presented in the literature. The generic feature is that these ghost cosmologies give rise to smooth transitions between radiation dominated phases (or more general power-law expansions) at early epochs and ghost dark matter resp. ghost dark energy dominated late epochs. The current age of our universe places us right at the non-linear transition phase. By studying the evolution backwards in time, we find that the dominance of the ghost over ordinary baryonic matter and radiative contributions persists back to the earliest times such that the Friedmann-Robertson-Walker geometry is dictated to a good approximation by the ghost alone. We also find that the Jeans instability occurs in the ghost dark energy scenario at late times, while it is absent in the ghost dark matter scenario.Comment: 31 pages, 9 figures; added references, clarified a few minor point

Carrier de-smearing of photoluminescence images on silicon wafers using the continuity equation

Photoluminescence images of silicon wafers with non-uniform lifetime distribution are often smeared by lateral carrier diffusion. We propose a simple method to de-smear the photoluminescence images by applying the two-dimensional continuity equation. We demonstrate the method on simulated silicon wafers and measured photoluminescence-based lifetime image of multicrystalline silicon wafer. The de-smearing is very effective in recovering the actual lifetime for wafers with gradual changes in lifetime but is less effective around localised recombination centres with high contrast such as grain boundaries and dislocations. The method is sensitive to measurement noise; therefore, the implementation of suitable noise filtering is often critical.This work was supported by the Australian Research Council and the Australian Renewable Energy Agency

Pulmonary surfactant inhibition following cardiopulmonary bypass

Following cardiopulmonary bypass (CPB) patients exhibit varying amounts of pulmonary dysfunction. This study examined the possibility that plasma which leaked into the alveoli could cause a reduction in the ability of pulmonary surfactant to reach very low surface tension (surfactant inhibition). The possibility that CPB could cause an increase in any component of plasma which might inhibit surfactant function was also examined. Plasma from adult and child patients was tested. Surfactant was prepared from pig lungs. Surfactant function was measured as ability to lower surface tension on a Langmuir-Wilhelmy balance. Plasma from normals and CPB patients before and after bypass was mixed with pig surfactant and tested on the balance. The surface load of surfactant was constant while the amount of plasma was varied. -- Plasma from normals, adult patients and child patients inhibited the surfactant. Serum, fibrinogen, albumin and globulins also inhibited surfactant in this assay. The amount of inhibition was proportional to the amount of protein added. No increased inhibition was seen in post-bypass vs. pre-bypass samples in adults or children. Inhibitor(s) are present in normal plasma and do not appear to be increased by the bypass procedure. It is possible that plasma components entering airspaces through leaking lung membranes may inhibit surfactant from proper function, and may contribute to lung collapse and edema seen in the ARDS of any etiology. -- The nature of the inhibition was examined by characterization of the inhibitor and by studying models of protein-surfactant interaction on the surface balance

Measurement of Intraspinal Pressure After Spinal Cord Injury: Technical Note from the Injured Spinal Cord Pressure Evaluation Study.

Intracranial pressure (ICP) is routinely measured in patients with severe traumatic brain injury (TBI). We describe a novel technique that allowed us to monitor intraspinal pressure (ISP) at the injury site in 14 patients who had severe acute traumatic spinal cord injury (TSCI), analogous to monitoring ICP after brain injury. A Codman probe was inserted subdurally to measure the pressure of the injured spinal cord compressed against the surrounding dura. Our key finding is that it is feasible and safe to monitor ISP for up to a week in patients after TSCI, starting within 72 h of the injury. With practice, probe insertion and calibration take less than 10 min. The ISP signal characteristics after TSCI were similar to the ICP signal characteristics recorded after TBI. Importantly, there were no associated complications. Future studies are required to determine whether reducing ISP improves neurological outcome after severe TSCI

Dopant concentration imaging in crystalline silicon wafers by band-to-band photoluminescence

In this work, we present two techniques for spatially resolved determination of the dopant density in silicon wafers. The first technique is based on measuring the formation rate of iron-acceptor pairs, which is monitored by band-to-band photoluminescence in low injection. This method provides absolute boron concentration images on p-type wafers, even if compensating dopants such as phosphorus are present, without reference to other techniques. The second technique is based on photoluminescence images of unpassivated wafers, where the excess carrier concentration is pinned by a high surface recombination rate. This rapid technique is applicable to either p- or n-type wafers, when the bulk carrier lifetime is much longer than the transit time to the surface. The relative sensitivities and advantages of the two techniques are discussed.This work has been supported by the Australian Research Council

Numerical Visualization of Dielectric Barrier Discharge Plasma Actuator Surface Discharge

A single dielectric barrier discharge is a specific configuration for plasma actuators consisting of two electrodes, one coated by a dielectric material and the other is exposed to the air. The purpose of this paper is to study the characteristics of single dielectric barrier discharge (DBD) plasma actuator through numerical modeling. A mathematical model that represents the physical system is presented and the numerical simulations for specific geometry are discussed in this paper. With this model, we can study the physics of the plasma flow. The formulation of the governing equations are divided into two since the physical system can be distinctly separated; one is the electrostatic part and the other is on the fluid flow. The electrostatic part is formulated using the Maxwell’s equation which needs to be modified to incorporate the current frequency equation so that the system of equations becomes unsteady which is more realistic compared to a steady system of equations. The fluid flow part is formulated using the Navier-Stokes equations. The equations are re-represented using a vorticity term and stream function so that the flow characteristics can be clearly visualized. All equations are discretized using finite difference method. The discretized equations are then solved using the Gauss-Seidel iteration method. The numerical results show that the vorticity of the plasma is similar in pattern at each time interval. The highest magnitude of the vorticity occurs at the inner part near end of the upper electrode but this magnitude is different at each time. On varying the applied voltage, it is found that the peak vorticity also increases. Therefore, this shows that both the applied voltage and the geometry of the system influence the characteristics of the plasma flow

Genetic characterization of Porcine Circovirus 2 found in Malaysia

Background: Porcine circovirus type 2 is the primary etiological agent associated with a group of complex multi-factorial diseases classified as Porcine Circovirus Associated Diseases (PCVAD). Sporadic cases reported in Malaysia in 2007 caused major economic losses to the 2.2 billion Malaysian ringgit (MYR) (approximately 0.7 billion US dollar) swine industry. The objective of the present study was to determine the association between the presence of PCV2 and occurrences of PCVAD. Results: This study showed that 37 out of 42 farms sampled were positive for PCV2 using PCR screening. Thirteen whole genome of PCV2 isolates from pigs with typical PCVAD symptoms were successfully sequenced. These isolates shared 98.3-99.2% similarities with sequences of isolates from the Netherlands. All thirteen isolates fell into the same clade as PCV2b isolates from other countries. Amino acid sequence analysis of the putative capsid protein (ORF2) of the PCV2 revealed that there are three clusters found in Malaysia, namely cluster 1C and 1A/1B. Of interest, three of the isolates (isolates Mal 005, Mal 006 and Mal 010) had a proline substitution for arginine or isoleucine encoded at nt. position 88-89. Eight of the isolates had mutations at the C terminus of the putative capsid protein suggestive of higher pathogenicity which may account for the high reports of PCVAD clinical symptoms in 2007. Conclusion: Phylogenetic study suggests that there may be a link between movements of animals by import of breeders into the country being the route of entry of the virus. While it is not possible to eradicate the virus from commercial pigs, the swine industry in Malaysia can be safeguarded by control measures implemented throughout the country. These measures should include improved biosecurity, disease surveillance; vaccination as well as enforcement of regulations formulated to control and prevent the spread of this disease on a national scale

Understanding interobserver variability of pathologists to improve oral epithelial dysplasia grading

\ua9 2024 The Author(s). Oral Diseases published by John Wiley & Sons Ltd. Objective: This study aimed to understand reasons for interobserver variability in the grading of oral epithelial dysplasia (OED) through a survey of pathologists to provide insight for improvements in the reliability and reproducibility of OED diagnoses. Methods: The study design included quantitative and qualitative methodology. A pre-validated 31-item questionnaire was distributed to general, head and neck, and oral and maxillofacial histopathology specialists worldwide. Results: A total of 132 pathologists participated and completed the questionnaire. Over two-thirds used the three-tier grading system for OED, while about a third used both binary and three-tier systems. Regular reporters of OED preferred the three-tier system and grading architectural features. Continuing education significantly aided recognition of architectural and cytological changes. Irregular epithelial stratification and drop-shaped rete ridges had the lowest prognostic value and recognition scores, while loss of epithelial cell cohesion had the highest. Most participants used clinical information and often sought a second opinion when grading OED. Conclusion: Our study has found that frequency of OED reporting and attendance of CME/CPD can play an important role in grading OED. Variations in the prognostic value of individual histological features and the use of clinical information may further contribute to interobserver variability