Stakeholder perspectives on the future of clean cooking in sub-Saharan Africa and the role of pay-as-you-go LPG in expanding access

Reliance on polluting cooking fuels is linked to three million premature deaths per year as well as other climatic, environmental and social impacts. Numerous clean cooking fuels are available but remain inaccessible to low-income consumers due to affordability limitations. An emerging solution targeting the urban poor is pay-as-you-go (PAYG) liquefied petroleum gas (LPG), which allows gas to be purchased in micropayments. However, little is known about whether this technology can scale and foster widespread adoption of clean cooking. This study examines the state of the clean cooking market in sub-Saharan Africa and the role of PAYG LPG through semi-structured interviews conducted with n = 20 key informants including academics, donors and practitioners. The findings revealed perceptions of slow progress and tensions around the roles of LPG and electricity in the fuel mix. However, there was broad consensus that LPG will play some role in the transition in the short term. Respondents also revealed the multitude of challenges faced by PAYG LPG providers attempting to scale this technology at a time of increasing controversy about the role of fossil fuels in Africa's energy transition. Nevertheless, participants described how PAYG LPG is an effective demand-side technology that makes clean cooking accessible to new consumers. Data collected by the meters offers opportunities to monetise impacts and target interventions at specific consumer groups. However, the unit economics are challenging and are compounded by a paucity of investment. Further research, dialogue and open debate between stakeholders is required to create a coherent enabling environment for PAYG LPG

Cleaning up the stack: Evaluating a clean cooking fuel stacking intervention in urban Kenya

There are a growing number of market-based providers of clean cooking solutions in sub-Saharan Africa that rely on use customer fuel sales to subsidise upfront cost of equipment. These business models can widen access to clean cooking but are undermined by the continued use of polluting fuels, known as “fuel stacking”, which limits provider revenues whilst perpetuating the negative impacts of cooking with traditional fuels. This study aimed to design and test a fuel stacking intervention with commercial pay-as-you-go LPG customers in Kisumu, Kenya. It consisted of three main phases: developing and testing a survey tool for diagnosing drivers of stacking (n = 99); using an intervention design framework (the Behaviour Change Wheel) to design an intervention consisting of the bundled provision of a pressure cooker, chapati pan and training; and testing the intervention in a small (n = 19) pre-post study. There was high uptake of the intervention, with the pans being used by all participants on roughly two-fifths of days. Target foods were cooked more frequently on LPG in the intervention phase, resulting in a significant increase in PAYG LPG use and an insignificant decrease in charcoal use. A third of participants stopped cooking with charcoal altogether, but some residual charcoal usage continued amongst the remainder. The results show that targeted stacking interventions can simultaneously promote sustained use of clean fuels and dis-adoption of polluting ones, resulting in commercial gains for clean cooking fuel providers. This could address the wicked problem of fuel stacking and accelerate progress towards Sustainable Development Goal 7

Synergies and trade-offs between sanitation and the sustainable development goals

To better leverage opportunities arising out of sustainable and inclusive management of sanitation services there is a need for robust and comprehensive evidence of the wide-ranging benefits that sanitation can deliver. The Sustainable Development Goals (SDGs) provide a comprehensive framework for sustainable development broken down into 169 interconnected Targets which are articulated under 17 Goals. Based on a methodology developed at University College London (UCL), this study identifies linkages between sanitation and the 169 Targets corroborated by published evidence. We show that there are synergies between sanitation and all 17 Goals and 130 (77%) of the Targets, and trade-offs for 28 (17%) of the Targets. We identified 83 Targets (49%) that call for action in the sanitation sector. The results demonstrate the far-reaching benefits that can be unlocked from investment in sanitation, which extend beyond health and spread across sectors. The evidence base for the 17 Goals establishes links that can inform cross-sectoral action, collaborations and investment across governance levels for integrated sanitation solutions. The research provides different stakeholders with a framework that can be applied to context-specific cases and projects. We propose a range of recommendations to policy makers, practitioners and researchers who seek to take this study further to help achieve the SDGs

Potential Nutrigenomic Approaches to Reduce the High Incidence of Obesity in Qatar

Obesity prevalence has been growing exponentially over the last few decades, with a high impact in high-income countries, like Qatar. Several approaches are attempting to understand the causes of this phenomenon however more important is what to do to reverse the trends. Obesity is widely studied, mostly in Europe and the Unites States, and a number of studies have demonstrate the role of specific gene patterns, transcriptome and proteome pathways, and gut microbiome strains. The Omics sciences have a great potential to investigate the determinants of non-communicable diseases, such as obesity. Nutritional genomics sciences apply all the Omics approaches to address nutrition-related diseases, investigating the interaction between genes and diet. To date, few data are available from nutrigenomic studies conducted in Middle East and particularly in Qatar to help the design of targeted interventions. The high incidence of obesity and the peculiar genetic make-up of the Qatari population provide opportunities for exploring nutrigenomic approaches to help addressing the problem

Microencapsulated islet allografts in diabetic NOD mice and nonhuman primates

OBJECTIVE: Our goal was to assess the efficacy of encapsulated allogeneic islets transplanted in diabetic NOD mice and streptozotocin (STZ)-diabetic nonhuman primates (NHPs).MATERIALS AND METHODS: Murine or NHP islets were microencapsulated and transplanted in non-immunosuppressed mice or NHPs given clinically-acceptable immunosuppressive regimens, respectively. Two NHPs were treated with autologous mesenchymal stem cells (MSCs) and peri-transplant oxygen therapy. Different transplant sites (intraperitoneal [i.p.], omental pouch, omental surface, and bursa omentalis) were tested in separate NHPs. Graft function was monitored by exogenous insulin requirements, fasting blood glucose levels, glucose tolerance tests, percent hemoglobin A1c (% HbA1c), and C-peptide levels. In vitro assessment of grafts included histology, immunohistochemistry, and viability staining; host immune responses were characterized by flow cytometry and cytokine/chemokine multiplex ELISAS.RESULTS: Microencapsulated islet allografts functioned long-term i.p. in diabetic NOD mice without immunosuppression, but for a relatively short time in immunosuppressed NHPs. In the NHPs, encapsulated allo-islets initially reduced hyperglycemia, decreased exogenous insulin requirements, elevated C-peptide levels, and lowered % HbA1c in plasma, but graft function diminished with time, regardless of transplant site. At necropsy, microcapsules were intact and non-fibrotic, but many islets exhibited volume loss, central necrosis and endogenous markers of hypoxia. Animals receiving supplemental oxygen and autologous MSCs showed improved graft function for a longer post-transplant period. In diabetic NHPs and mice, cell-free microcapsules did not elicit a fibrotic response.CONCLUSIONS: The evidence suggested that hypoxia was a major factor for damage to encapsulated islets in vivo. To achieve long-term function, new approaches must be developed to increase the oxygen supply to microencapsulated islets and/or identify donor insulin-secreting cells which can tolerate hypoxia.</p

Search for the standard model Higgs boson in the H to ZZ to 2l 2nu channel in pp collisions at sqrt(s) = 7 TeV

A search for the standard model Higgs boson in the H to ZZ to 2l 2nu decay channel, where l = e or mu, in pp collisions at a center-of-mass energy of 7 TeV is presented. The data were collected at the LHC, with the CMS detector, and correspond to an integrated luminosity of 4.6 inverse femtobarns. No significant excess is observed above the background expectation, and upper limits are set on the Higgs boson production cross section. The presence of the standard model Higgs boson with a mass in the 270-440 GeV range is excluded at 95% confidence level.Comment: Submitted to JHE

Search for New Physics with Jets and Missing Transverse Momentum in pp collisions at sqrt(s) = 7 TeV

A search for new physics is presented based on an event signature of at least three jets accompanied by large missing transverse momentum, using a data sample corresponding to an integrated luminosity of 36 inverse picobarns collected in proton--proton collisions at sqrt(s)=7 TeV with the CMS detector at the LHC. No excess of events is observed above the expected standard model backgrounds, which are all estimated from the data. Exclusion limits are presented for the constrained minimal supersymmetric extension of the standard model. Cross section limits are also presented using simplified models with new particles decaying to an undetected particle and one or two jets

Search for anomalous t t-bar production in the highly-boosted all-hadronic final state

A search is presented for a massive particle, generically referred to as a Z', decaying into a t t-bar pair. The search focuses on Z' resonances that are sufficiently massive to produce highly Lorentz-boosted top quarks, which yield collimated decay products that are partially or fully merged into single jets. The analysis uses new methods to analyze jet substructure, providing suppression of the non-top multijet backgrounds. The analysis is based on a data sample of proton-proton collisions at a center-of-mass energy of 7 TeV, corresponding to an integrated luminosity of 5 inverse femtobarns. Upper limits in the range of 1 pb are set on the product of the production cross section and branching fraction for a topcolor Z' modeled for several widths, as well as for a Randall--Sundrum Kaluza--Klein gluon. In addition, the results constrain any enhancement in t t-bar production beyond expectations of the standard model for t t-bar invariant masses larger than 1 TeV.Comment: Submitted to the Journal of High Energy Physics; this version includes a minor typo correction that will be submitted as an erratu

Measurement of the t t-bar production cross section in the dilepton channel in pp collisions at sqrt(s) = 7 TeV

The t t-bar production cross section (sigma[t t-bar]) is measured in proton-proton collisions at sqrt(s) = 7 TeV in data collected by the CMS experiment, corresponding to an integrated luminosity of 2.3 inverse femtobarns. The measurement is performed in events with two leptons (electrons or muons) in the final state, at least two jets identified as jets originating from b quarks, and the presence of an imbalance in transverse momentum. The measured value of sigma[t t-bar] for a top-quark mass of 172.5 GeV is 161.9 +/- 2.5 (stat.) +5.1/-5.0 (syst.) +/- 3.6(lumi.) pb, consistent with the prediction of the standard model.Comment: Replaced with published version. Included journal reference and DO