22 research outputs found
Breaking bad conduits: 'resleeving' the intrathoracic gastric conduit post oesophagectomy
Urine based detection of intestinal mucosal cell damage in neonates with suspected necrotising enterocolitis
Ultrastructural observations on the droplets of experimentally-induced goitres in Xenopus laevis with especial reference to the development of uhlenhuth colloid cells
Surgical intervention does not affect short-term plasma citrulline levels in infants: implications for citrulline as a marker of postoperative intestinal complications
Necrotising enterocolitis
Necrotising enterocolitis (NEC) is a devastating disease of infants and the commonest gastrointestinal emergency in the newborn period. It is a condition characterised by intestinal necrosis affecting the ileum and/or colon. There is a wide spectrum of clinical manifestations. In the least severe cases there may be mild inflammation of the intestinal wall in a baby with mild abdominal distension and minimal systemic upset. The most severely affected cases, however, may show evidence of full thickness intestinal necrosis with perforation, respiratory and cardiovascular collapse, multi-system organ failure and in some cases death