Lhermitte-duclos Disease - a Case-report

We report one case of histologically proved Lhermitte-Duclos disease. Suspected on the basis of CT and angiography, the pre-operative diagnosis has been confirmed by the characteristic features of the lesion on MRI: a unilateral posterior fossa mass, hyperintense on proton density and T2-weighted images, hypointense on T1-weighted images, non enhancing after Gd administration. The gyral pattern was preserved, but a specific thickening of cerebellar folia was demonstrated. Despite a good post-operative short term prognosis, recurrence may occur. With a better depiction of lesion limits, MRI could improve the surgical approach and reduce the risk of subtotal excision

MRI assessment of unsuspected dural sinus thrombosis.

In three patients with clinically unsuspected diagnosis, MRI has afforded a positive and conspicuous demonstration of dural sinus thrombosis, allowing specific treatment and followed by improvement in the patients' condition. Even in retrospect, CT examinations were nondiagnostic. Presenting symptoms were usual and nonspecific. CT and radionuclide scanning have proved valuable when performed on a clinically oriented basis. Angiography cannot be carried out without clear indications. MRI offers advantages in being a non-invasive technique without ionising radiation, allowing direct visualization and accurate delineation of the thrombus. MRI is definitely the method of choice to assess clinically suspected cerebral venous occlusion. As MRI diagnosis relies on a routine examination protocol, we believe that it will detect other unsuspected cases of dural sinus thrombosis