Protein evolution

Among the proteins that have evolved over hundreds of millions of years, with important roles in defence against invading micro-organisms, are the pentraxins. The two major members of the family are known as CRP and SAP, and they evolve due to mutations in the underlying DNA. The Study Group was asked to construct a model of this evolution in order to answer specific questions about the occurrences of these proteins in man and in the horseshoe crab

Microlensing variability in time-delay quasars

We have searched for microlensing variability in the light curves of five gravitationally lensed quasars with well-determined time delays: SBS 1520+530, FBQ 0951+2635, RX J0911+0551, B1600+434 and HE 2149-2745. By comparing the light curve of the leading image with a suitably time offset light curve of a trailing image we find that two (SBS 1520+530 and FBQ 0951+2635) out of the five quasars have significant long-term (years) and short-term (100 days) brightness variations that may be attributed to microlensing.The short-term variations may be due to nanolenses, relativistic hot or cold spots in the quasar accretion disks, or coherent microlensing at large optical depth.Comment: 12 pages, 5 figures, uses natbib.sty and aa.cl

Water resources management in a homogenizing world: Averting the Growth and Underinvestment trajectory

Biotic homogenization, a de facto symptom of a global biodiversity crisis, underscores the urgency of reforming water resources management to focus on the health and viability of ecosystems. Global population and economic growth, coupled with inadequate investment in maintenance of ecological systems, threaten to degrade environmental integrity and ecosystem services that support the global socioeconomic system, indicative of a system governed by the Growth and Underinvestment (G&U) archetype. Water resources management is linked to biotic homogenization and degradation of system integrity through alteration of water systems, ecosystem dynamics, and composition of the biota. Consistent with the G&U archetype, water resources planning primarily treats ecological considerations as exogenous constraints rather than integral, dynamic, and responsive parts of the system. It is essential that the ecological considerations be made objectives of water resources development plans to facilitate the analysis of feedbacks and potential trade-offs between socioeconomic gains and ecological losses. We call for expediting a shift to ecosystem-based management of water resources, which requires a better understanding of the dynamics and links between water resources management actions, ecological side-effects, and associated long-term ramifications for sustainability. To address existing knowledge gaps, models that include dynamics and estimated thresholds for regime shifts or ecosystem degradation need to be developed. Policy levers for implementation of ecosystem-based water resources management include shifting away from growth-oriented supply management, better demand management, increased public awareness, and institutional reform that promotes adaptive and transdisciplinary management approaches

Simulated Dark-Matter Halos as a Test of Nonextensive Statistical Mechanics

In the framework of nonextensive statistical mechanics, the equilibrium structures of astrophysical self-gravitating systems are stellar polytropes, parameterized by the polytropic index n. By careful comparison to the structures of simulated dark-matter halos we find that the density profiles, as well as other fundamental properties, of stellar polytropes are inconsistent with simulations for any value of n. This result suggests the need to reconsider the applicability of nonextensive statistical mechanics (in its simplest form) to equilibrium self-gravitating systems.Comment: Accepted for publication in Physical Review

Delayed soft X-ray emission lines in the afterglow of GRB 030227

Strong, delayed X-ray line emission is detected in the afterglow of GRB 030227, appearing near the end of the XMM-Newton observation, nearly twenty hours after the burst. The observed flux in the lines, not simply the equivalent width, sharply increases from an undetectable level (<1.7e-14 erg/cm^2/s, 3 sigma) to 4.1e-14 erg/cm^2/s in the final 9.7 ks. The line emission alone has nearly twice as many detected photons as any previous detection of X-ray lines. The lines correspond well to hydrogen and/or helium-like emission from Mg, Si, S, Ar and Ca at a redshift z=1.39. There is no evidence for Fe, Co or Ni--the ultimate iron abundance must be less than a tenth that of the lighter metals. If the supernova and GRB events are nearly simultaneous there must be continuing, sporadic power output after the GRB of a luminosity >~5e46 erg/s, exceeding all but the most powerful quasars.Comment: Submitted to ApJL. 14 pages, 3 figures with AASLaTe

Swift Identification of Dark Gamma-Ray Bursts

We present an optical flux vs. X-ray flux diagram for all known gamma-ray bursts (GRBs) for which an X-ray afterglow has been detected. We propose an operational definition of dark bursts as those bursts that are optically subluminous with respect to the fireball model, i.e., which have an optical-to-X-ray spectral index beta_OX < 0.5. Out of a sample of 52 GRBs we identify 5 dark bursts. The definition and diagram serve as a simple and quick diagnostic tool for identifying dark GRBs based on limited information, particularly useful for early and objective identification of dark GRBs observed with the Swift satellite.Comment: 4 pages, 1 figure. ApJ Letters, in pres

Arrays of Josephson junctions in an environment with vanishing impedance

The Hamiltonian operator for an unbiased array of Josephson junctions with gate voltages is constructed when only Cooper pair tunnelling and charging effects are taken into account. The supercurrent through the system and the pumped current induced by changing the gate voltages periodically are discussed with an emphasis on the inaccuracies in the Cooper pair pumping. Renormalisation of the Hamiltonian operator is used in order to reliably parametrise the effects due to inhomogeneity in the array and non-ideal gating sequences. The relatively simple model yields an explicit, testable prediction based on three experimentally motivated and determinable parameters.Comment: 13 pages, 9 figures, uses RevTeX and epsfig, Revised version, Better readability and some new result

Spectroscopic confirmation of a cluster of galaxies at z=1 in the field of the gravitational lens MG2016+112

We present new optical data on the cluster AX J2019+1127 identified by the X-ray satellite ASCA at z\sim 1 (Hattori et al. 1997). The data suggest the presence of a high-redshift cluster of galaxies responsible for the large separation triple quasar MG2016+112. Our deep photometry reveals an excess of z\sim 1 galaxy candidates, as already suspected by Benitez et al. (1999). Our spectroscopic survey of 44 objects in the field shows an excess of 6 red galaxies securely identified at z \sim 1, with a mean redshift of z =1.005 +/- 0.002. We estimate a velocity dispersion of \sigma = 771 (+430/-160) km s(-1) based on these 6 galaxies and a V-band mass-to-light ratio of 215 (+308/-77) h_50 M/L_sol. Our observations thus confirm the existence of a massive structure acting as the lens, which explains the unusual configuration of the triple quasar. Hence, there is no more need to invoke the existence of a ``dark cluster'' to understand this lens system.Comment: 8 pages, 4 figures, uses aa.cls, accepted to Astronomy and Astrophysics with minor change