2,804 research outputs found
Soliciting Sophisticates: A Modest Proposal for Attorney Solicitation
This Note advocates an amendment to the ethical standards governing attorneys that will permit the personal solicitation for pecuniary gain of sophisticated prospective clients - that is, those persons having general knowledge of their legal needs and the expertise to assess adequately the information and presentation of an attorney. Part I of this Note shows that lawyer solicitation is a form of commercial speech under recent Supreme Court decisions. It also asserts that, though the traditional reasons for banning lawyer solicitation still have some validity, these reasons do not justify prohibiting the solicitation of sophisticated clients. Part II suggests some potential benefits to the legal profession and clients resulting from the proposed solicitation amendment. In Part III, this Note offers a bright-line standard for sophistication that the bar might apply to this amendment so that lawyers can better determine the propriety of their activities. Finally, this Note concludes that adopting the amendment to permit the solicitation of sophisticated persons will not drastically change the way lawyers attract new clients, and will benefit both lawyers and consumers of legal services by recognizing their legitimate commercial speech interests
Transfected poly(I:C) activates different dsRNA receptors leading to apoptosis or immunoadjuvant response in androgen-independent prostate cancer cells
Background: Castration-resistant prostate cancer (CRPC) is refractory to chemo-radiotherapy.
Results: Transfection of the synthetic analog of dsRNA poly(I:C) simultaneously stimulates apoptosis and IFN- expression
through different pathways in androgen-independent prostate cancer (PCa) cells.
Conclusion: Dual parallel pathways triggered by distinct receptors activate direct and immunologically mediated antitumor
effects in advanced PCa.
Significance: The proapoptotic/immunoadjuvant poly(I:C)-Lipofectamine complex may offer new therapeutic insights into CRPC
Upper critical field in {BaKBiO}: magnetotransport versus magnetotunneling
Elastic tunneling is used as a powerful direct tool to determine the upper
critical field in the high- oxide BaKBiO. The
temperature dependence of inferred from the tunneling follows the
Werthamer-Helfand-Hohenberg prediction for type-II superconductors. A
comparison will be made with resistively determined critical field data.Comment: 4 pages incl. 5 figure
Analytical formulas for calculating the thermal diffusivity of cylindrical shell and spherical shell samples
Calculating the thermal diffusivity of solid materials is commonly carried
out using the laser flash experiment. This classical experiment considers a
small (usually thin disc-shaped) sample of the material with parallel front and
rear surfaces, applying a heat pulse to the front surface and recording the
resulting rise in temperature over time on the rear surface. Recently, Carr and
Wood [Int J Heat Mass Transf, 144 (2019) 118609] showed that the thermal
diffusivity can be expressed analytically in terms of the heat flux function
applied at the front surface and the temperature rise history at the rear
surface. In this paper, we generalise this result to radial unidirectional heat
flow, developing new analytical formulas for calculating the thermal
diffusivity for cylindrical shell and spherical shell shaped samples. Two
configurations are considered: (i) heat pulse applied on the inner surface and
temperature rise recorded on the outer surface and (ii) heat pulse applied on
the outer surface and temperature rise recorded on the inner surface. Code
implementing and verifying the thermal diffusivity formulas for both
configurations is made available.Comment: 12 pages, 5 figure
Agroecology in the curricula of the Faculty of Agricultural Sciences of the UNCUYO : contributions to the territorial planning
Fil: Studer, P. M..
Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias. Departamento de IngenierÃa AgrÃcolaFil: Viani, M. .
Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias. Departamento de IngenierÃa AgrÃcolaFil: Filippini, MarÃa Flavia.
Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias. Departamento de IngenierÃa AgrÃcol
Constraints on Dark Matter from Colliders
We show that colliders can impose strong constraints on models of dark
matter, in particular when the dark matter is light. We analyze models where
the dark matter is a fermion or scalar interacting with quarks and/or gluons
through an effective theory containing higher dimensional operators which
represent heavier states that have been integrated out of the effective field
theory. We determine bounds from existing Tevatron searches for monojets as
well as expected LHC reaches for a discovery. We find that colliders can
provide information which is complementary or in some cases even superior to
experiments searching for direct detection of dark matter through its
scattering with nuclei. In particular, both the Tevatron and the LHC can
outperform spin dependent searches by an order of magnitude or better over much
of parameter space, and if the dark matter couples mainly to gluons, the LHC
can place bounds superior to any spin independent search.Comment: 23 pages, 16 figure
Simplified models of diffusion in radially-symmetric geometries
We consider diffusion-controlled release of particles from -dimensional
radially-symmetric geometries. A quantity commonly used to characterise such
diffusive processes is the proportion of particles remaining within the
geometry over time, denoted as . The stochastic approach for computing
is time-consuming and lacks analytical insight into key parameters while
the continuum approach yields complicated expressions for that obscure
the influence of key parameters and complicate the process of fitting
experimental release data. In this work, to address these issues, we develop
several simple surrogate models to approximate by matching moments with
the continuum analogue of the stochastic diffusion model. Surrogate models are
developed for homogeneous slab, circular, annular, spherical and spherical
shell geometries with a constant particle movement probability and
heterogeneous slab, circular, annular and spherical geometries, comprised of
two concentric layers with different particle movement probabilities. Each
model is easy to evaluate, agrees well with both stochastic and continuum
calculations of and provides analytical insight into the key parameters
of the diffusive transport system: dimension, diffusivity, geometry and
boundary conditions.Comment: 22 pages, 3 figures, submitte
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