170 research outputs found
Flux-loss of buoyant ropes interacting with convective flows
We present 3-d numerical magneto-hydrodynamic simulations of a buoyant,
twisted magnetic flux rope embedded in a stratified, solar-like model
convection zone. The flux rope is given an initial twist such that it neither
kinks nor fragments during its ascent. Moreover, its magnetic energy content
with respect to convection is chosen so that the flux rope retains its basic
geometry while being deflected from a purely vertical ascent by convective
flows. The simulations show that magnetic flux is advected away from the core
of the flux rope as it interacts with the convection. The results thus support
the idea that the amount of toroidal flux stored at or near the bottom of the
solar convection zone may currently be underestimated.Comment: 5 pages, 3 figures. Accepted for publication in Astronomy &
Astrophysic
Learning Stochastic Majority Votes by Minimizing a PAC-Bayes Generalization Bound
We investigate a stochastic counterpart of majority votes over finite ensembles of classifiers, and study its generalization properties. While our approach holds for arbitrary distributions, we instantiate it with Dirichlet distributions: this allows for a closed-form and differentiable expression for the expected risk, which then turns the generalization bound into a tractable training objective.The resulting stochastic majority vote learning algorithm achieves state-of-the-art accuracy and benefits from (non-vacuous) tight generalization bounds, in a series of numerical experiments when compared to competing algorithms which also minimize PAC-Bayes objectives -- both with uninformed (data-independent) and informed (data-dependent) priors
Relationship between cellular response and behavioral variability in bacterial chemotaxis
Bacterial chemotaxis in Escherichia coli is a canonical system for the study
of signal transduction. A remarkable feature of this system is the coexistence
of precise adaptation in population with large fluctuating cellular behavior in
single cells (Korobkova et al. 2004, Nature, 428, 574). Using a stochastic
model, we found that the large behavioral variability experimentally observed
in non-stimulated cells is a direct consequence of the architecture of this
adaptive system. Reversible covalent modification cycles, in which methylation
and demethylation reactions antagonistically regulate the activity of
receptor-kinase complexes, operate outside the region of first-order kinetics.
As a result, the receptor-kinase that governs cellular behavior exhibits a
sigmoidal activation curve. This curve simultaneously amplifies the inherent
stochastic fluctuations in the system and lengthens the relaxation time in
response to stimulus. Because stochastic fluctuations cause large behavioral
variability and the relaxation time governs the average duration of runs in
response to small stimuli, cells with the greatest fluctuating behavior also
display the largest chemotactic response. Finally, Large-scale simulations of
digital bacteria suggest that the chemotaxis network is tuned to simultaneously
optimize the random spread of cells in absence of nutrients and the cellular
response to gradients of attractant.Comment: 15 pages, 4 figures, Supporting information available here
http://cluzel.uchicago.edu/data/emonet/arxiv_070531_supp.pd
On mesogranulation, network formation and supergranulation
We present arguments which show that in all likelihood mesogranulation is not
a true scale of solar convection but the combination of the effects of both
highly energetic granules, which give birth to strong positive divergences
(SPDs) among which we find exploders, and averaging effects of data processing.
The important role played by SPDs in horizontal velocity fields appears in the
spectra of these fields where the scale 4 Mm is most energetic; we
illustrate the effect of averaging with a one-dimensional toy model which shows
how two independent non-moving (but evolving) structures can be transformed
into a single moving structure when time and space resolution are degraded.
The role of SPDs in the formation of the photospheric network is shown by
computing the advection of floating corks by the granular flow. The coincidence
of the network bright points distribution and that of the corks is remarkable.
We conclude with the possibility that supergranulation is not a proper scale of
convection but the result of a large-scale instability of the granular flow,
which manifests itself through a correlation of the flows generated by SPDs.Comment: 10 pages, 11 figures, to appear in Astronomy and Astrophysic
Alpha effect due to buoyancy instability of a magnetic layer
A strong toroidal field can exist in form of a magnetic layer in the
overshoot region below the solar convection zone. This motivates a more
detailed study of the magnetic buoyancy instability with rotation. We calculate
the alpha effect due to helical motions caused by a disintegrating magnetic
layer in a rotating density-stratified system with angular velocity Omega
making an angle theta with the vertical. We also study the dependence of the
alpha effect on theta and the strength of the initial magnetic field. We carry
out three-dimensional hydromagnetic simulations in Cartesian geometry. A
turbulent EMF due to the correlations of the small scale velocity and magnetic
field is generated. We use the test-field method to calculate the transport
coefficients of the inhomogeneous turbulence produced by the layer. We show
that the growth rate of the instability and the twist of the magnetic field
vary monotonically with the ratio of thermal conductivity to magnetic
diffusivity. The resulting alpha effect is inhomogeneous and increases with the
strength of the initial magnetic field. It is thus an example of an
"anti-quenched" alpha effect. The alpha effect is nonlocal, requiring around
8--16 Fourier modes to reconstruct the actual EMF based on the actual mean
field.Comment: 14 pages, 19 figures 3 tables (submitted to A & A
Dynamic Coupling of Convective Flows and Magnetic Field during Flux Emergence
We simulate the buoyant rise of a magnetic flux rope from the solar
convection zone into the corona to better understand the energetic coupling of
the solar interior to the corona. The magnetohydrodynamic model addresses the
physics of radiative cooling, coronal heating and ionization, which allow us to
produce a more realistic model of the solar atmosphere. The simulation
illustrates the process by which magnetic flux emerges at the photosphere and
coalesces to form two large concentrations of opposite polarities. We find that
the large-scale convective motion in the convection zone is critical to form
and maintain sunspots, while the horizontal converging flows in the near
surface layer prevent the concentrated polarities from separating. The foot
points of the sunspots in the convection zone exhibit a coherent rotation
motion, resulting in the increasing helicity of the coronal field. Here, the
local configuration of the convection causes the convergence of opposite
polarities of magnetic flux with a shearing flow along the polarity inversion
line. During the rising of the flux rope, the magnetic energy is first injected
through the photosphere by the emergence, followed by energy transport by
horizontal flows, after which the energy is subducted back to the convection
zone by the submerging flows
Simulation of Flux Emergence from the Convection Zone to the Corona
Here, we present numerical simulations of magnetic flux buoyantly rising from
a granular convection zone into the low corona. We study the complex
interaction of the magnetic field with the turbulent plasma. The model includes
the radiative loss terms, non-ideal equations of state, and empirical corona
heating. We find that the convection plays a crucial role in shaping the
morphology and evolution of the emerging structure. The emergence of magnetic
fields can disrupt the convection pattern as the field strength increases, and
form an ephemeral region-like structure, while weak magnetic flux emerges and
quickly becomes concentrated in the intergranular lanes, i.e. downflow regions.
As the flux rises, a coherent shear pattern in the low corona is observed in
the simulation. In the photosphere, both magnetic shearing and velocity
shearing occur at a very sharp polarity inversion line (PIL). In a case of
U-loop magnetic field structure, the field above the surface is highly sheared
while below it is relaxed
Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis(1.).
Treponema pallidum PCR (Tp-PCR) has been noted as a valid method for diagnosing syphilis. We compared Tp-PCR to a combination of darkfield microscopy (DFM), the reference method, and serologic testing in a cohort of 273 patients from France and Switzerland and found the diagnostic accuracy of Tp-PCR was higher than that for DFM
Feedback control architecture and the bacterial chemotaxis network.
PMCID: PMC3088647This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Bacteria move towards favourable and away from toxic environments by changing their swimming pattern. This response is regulated by the chemotaxis signalling pathway, which has an important feature: it uses feedback to 'reset' (adapt) the bacterial sensing ability, which allows the bacteria to sense a range of background environmental changes. The role of this feedback has been studied extensively in the simple chemotaxis pathway of Escherichia coli. However it has been recently found that the majority of bacteria have multiple chemotaxis homologues of the E. coli proteins, resulting in more complex pathways. In this paper we investigate the configuration and role of feedback in Rhodobacter sphaeroides, a bacterium containing multiple homologues of the chemotaxis proteins found in E. coli. Multiple proteins could produce different possible feedback configurations, each having different chemotactic performance qualities and levels of robustness to variations and uncertainties in biological parameters and to intracellular noise. We develop four models corresponding to different feedback configurations. Using a series of carefully designed experiments we discriminate between these models and invalidate three of them. When these models are examined in terms of robustness to noise and parametric uncertainties, we find that the non-invalidated model is superior to the others. Moreover, it has a 'cascade control' feedback architecture which is used extensively in engineering to improve system performance, including robustness. Given that the majority of bacteria are known to have multiple chemotaxis pathways, in this paper we show that some feedback architectures allow them to have better performance than others. In particular, cascade control may be an important feature in achieving robust functionality in more complex signalling pathways and in improving their performance
DOT tomography of the solar atmosphere. IV. Magnetic patches in internetwork areas
We use G-band and Ca II H image sequences from the Dutch Open Telescope (DOT)
to study magnetic elements that appear as bright points in internetwork parts
of the quiet solar photosphere and chromosphere. We find that many of these
bright points appear recurrently with varying intensity and horizontal motion
within longer-lived magnetic patches. We develop an algorithm for detection of
the patches and find that all patches identified last much longer than the
granulation. The patches outline cell patterns on mesogranular scales,
indicating that magnetic flux tubes are advected by granular flows to
mesogranular boundaries. Statistical analysis of the emergence and
disappearance of the patches points to an average patch lifetime as long as
530+-50 min (about nine hours), which suggests that the magnetic elements
constituting strong internetwork fields are not generated by a local turbulent
dynamo.Comment: 8 pages, 6 figure
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