The U wave in atrial fibrillation

The U wave in ECGs of patients is difficult to observe because it is hidden under the atrial fibrillatory wave. Measurement and characteristics of the U wave in atrial fibrillation have not previously been described. Beat averaging was used to reveal the U waves in 12-lead ECGs of 8 patients with atrial fibrillation taking account of heart rate dependency of U wave characteristics. U wave polarity and amplitude in 12-lead ECG and the amplitude ratio of U wave to atrial fibrillatory wave in lead VI were measured. U waves were measureable in all patients. U waves were predominantly positive in leads 1. 11. aVF. V2. V3, V4, V5 and V6, negative in leads aVR. Amplitudes were largest in the precordial leads measuring up to 55 fJ V. In lead VI the U wave amplitude was on average 0.17 (range 0.1 to 0.4) times the amplitude of the atrial fibrillatory wave. U waves can be measured by ventricular beat averaging in AF patients. U waves were normal in this small group of patients

Ballistic impact on composite armour

Armoured vehicles in current military service are requiring ever more protection to enable them to carry out their mission in a safe, effective manner. This requirement is driving vehicle weight up to such an extent that the logistics of vehicle transport is becoming increasingly difficult. Composite materials are an important material group whose high specific properties can enable structures to be manufactured for a far lower weight than might otherwise be possible. Composite materials in an armoured vehicle will require structural performance as well as ballistic performance. The mechanical and ballistic performance of tl-kk armour and structural composites has been investigated against dcformable and armour-piercing ammunitions, over a range of impact velocities. Testing has indicated that heavy/coarse reinforcement weaves perform well against deformable ammunition and light/fine weaves well against armour piercing ammunition. The effect of individual mechanical properties on ballistic performance has been investigated as has the damage morphology of impacted materials. High tensile strength combined with low fracture toughness has been identified as an important requirement. Failure mechanisms have been identified from sections of ballistic impacts and through the use of mechanical test data the energy absorbed by each mechanism has been calculated. An energy audit has been carried out of all materials tested and a modelling procedure developed based on mechanical characteristics, damage morphology and failure mechanisms. This model has been tested against literature results and found to give very satisfactory performance

Historical Grassland Turboveg Database Project. 2067 Relevés recorded by Dr Austin O’ Sullivan 1962 – 1982

User Guide and CD of Database are availableEnd of project reportThe more common grassland types occupy about 70% of the Irish landscape (O’Sullivan, 1982), but information on these vegetation types is rare. Generally, Irish grasslands are distinguished based on the intensity of their management (improved or semi-natural grasslands), and the drainage conditions and acidity of the soil (dry or wet, calcareous or acidic grassland types) (Fossitt, 2000). However, little is known about their floristic composition and the changes in floristic composition over time. The current knowledge on grassland vegetation is mostly based on a survey of Irish grasslands by Dr. Austin O’Sullivan completed in the 1960’s and 1970’s (O’Sullivan, 1982). In this survey O’Sullivan identified Irish grassland types in accordance with the classification of continental European grasslands based on the principles of the School of Phytosociology. O’Sullivan distinguished five main grassland types introducing agricultural criteria as well as floristic criteria into grassland classification (O’Sullivan, 1982). In 1978, O’Sullivan made an attempt at mapping Ireland’s vegetation types including the five grassland types distinguished in his later publication as well as two types of peatland vegetation (Figures 1 and 2). This map was completed using 1960’s soils maps (National Soil Survey, Teagasc, Johnstown Castle) and a subsample of the dataset on the composition of Irish grasslands. Phytosociological classification of vegetation is based on the full floristic composition of the vegetation as determined by assessing the abundance and spatial structure of the plant species in a given area. The actual area of the survey (or relevé) is determined according to strict criteria, which include how representative the sample area is for the wider vegetation (i.e. how many of the species found in the wider area are also present in the survey area).National Parks and Wildlife Service of the Department of the Environment, Heritage and Local Government, Dublin, Ireland

A Framework for Supporting Immersion in Commodity Gaming

Presented here is a case for a higher level ofengagement and immersion in gaming by proposing gamingsoftware support for displays that engage the players peripheralvision. It is widely accepted that the sense of “being there” or“presence” is heightened by “removing the frame”, that is, fillingthe viewers field of view with a virtual environment. Except for afew special cases this is almost entirely unsupported in currentcommodity games, and yet the importance is readily accepted asis illustrated by the widespread use in commercial simulators andvirtual reality environments. This paper will present the generalrequirements necessary to support a range of seamless immersivedisplays, that is, displays that engage a significant portion, if notall, of the users field of view. It will further outline a softwarepipeline split into two parts, a generic section that generates thenecessary visual information followed by a section that handlesthe device/display specific details.Part of the motivation stems from the realisation that there aremany possible hardware configurations for immersive displaysand it would be too high a burden on the software developer tosupport them all. Equally the installation supplier does not haveaccess to the underlying software engine or source code. Theproposed solution then is to separate the problem into two pieces,those that are the responsibility of the software developer andthose that are the responsibility of the display provider

CO and CH3OH observations of the BHR71 outflows with APEX

Context : Highly-collimated outflows are believed to be the earliest stage in outflow evolution, so their study is essential for understanding the processes driving outflows. The BHR71 Bok globule is known to harbour such a highly-collimated outflow, which is powered by a protostar belonging to a protobinary system. Aims : We aimed at investigating the interaction of collimated outflows with the ambient molecular cloud by using molecular tracers. Methods : We mapped the BHR71 highly-collimated outflow in CO(3-2) with the APEX telescope, and observed several bright points of the outflow in the molecular transitions CO(4-3), 13CO(3-2), C18O(3-2), and CH3OH(7-6). We use an LVG code to characterise the temperature enhancements in these regions. Results : In our CO(3-2) map, the second outflow driven by IRS2, which is the second source of the binary system, is completely revealed and shown to be bipolar. We also measure temperature enhancements in the lobes. The CO and methanol LVG modelling points to temperatures between 30 and 50K in the IRS1 outflow, while the IRS2 outflow seems to be warmer (up to 300K).Comment: 4 pages, 5 Figures, accepted by A&A Letters, to appear in the APEX First results special issu

Recurring patterns of atrial fibrillation in surface ECG predict restoration of sinus rhythm by catheter ablation

Background Non-invasive tools to help identify patients likely to benefit from catheter ablation (CA) of atrial fibrillation (AF) would facilitate personalised treatment planning. Aim To investigate atrial waveform organisation through recurrence plot indices (RPI) and their ability to predict CA outcome. Methods One minute 12-lead ECG was recorded before CA from 62 patients with AF (32 paroxysmal AF; 45 men; age 57±10 years). Organisation of atrial waveforms from i) TQ intervals in V1 and ii) QRST suppressed continuous AF waveforms (CAFW), were quantified using RPI: percentage recurrence (PR), percentage determinism (PD), entropy of recurrence (ER). Ability to predict acute (terminating vs. non-terminating AF), 3-month and 6-month postoperative outcome (AF vs. AF free) were assessed. Results RPI either by TQ or CAFW analysis did not change significantly with acute outcome. Patients arrhythmia-free at 6-month follow-up had higher organisation in TQ intervals by PD (

Association of Oral Anticoagulation Prescription with Clinical Events in Patients with an Asymptomatic Unrepaired Abdominal Aortic Aneurysm

Background: Most abdominal aortic aneurysms (AAA) have large volumes of intraluminal thrombus which has been implicated in promoting the risk of major adverse events. The aim of this study was to examine the association of therapeutic anticoagulation with AAA-related events and major adverse cardiovascular events (MACE) in patients with an unrepaired AAA. Methods: Patients with an asymptomatic unrepaired AAA were recruited from four sites in Australia. The primary outcome was the combined incidence of AAA repair or AAA rupture-related mortality (AAA-related events). The main secondary outcome was MACE (the combined incidence of myocardial infarction, stroke, or cardiovascular death). The associations of anticoagulation with these outcomes were assessed using Cox proportional hazard analyses (reporting hazard ratio, HR, and 95% confidence intervals, CI) to adjust for other risk factors. Results: A total of 1161 patients were followed for a mean (standard deviation) of 4.9 (4.0) years. Of them, 536 (46.2%) patients had a least one AAA-related event and 319 (27.5%) at least one MACE. In the sample, 98 (8.4%) patients were receiving long-term therapeutic anticoagulation using warfarin (84), apixaban (7), rivaroxaban (6), or dabigatran (1). Prescription of an anticoagulant was associated with a reduced risk of an AAA-related event (adjusted HR 0.61; 95% CI 0.42, 0.90, p = 0.013), but not MACE (HR 1.16; 95% CI 0.78, 1.72, p = 0.476). Conclusions: These findings suggest that AAA-related events but not MACE may be reduced in patients prescribed an anticoagulant medication. Due to the inherent biases of observational studies, a randomized controlled trial is needed to assess whether anticoagulation reduces the risk of AAA-related events

The impact of the grazing animal on phosphorus, nitrogen, potassium and suspended solids loss from grazed pastures, Part A

Teagasc wishes to acknowledge the support of the Environmental Research Technological Development and Innovation (ERTDI) Programme under the Productive Sector Operational Programme which was financed by the Irish Government under the National Development Plan 2000-2006.End of project reportIn Ireland 90% of the 4.2 million ha of farmland is grassland. Phosphorus deficiency limited grassland production in Ireland and this was corrected by chemical fertiliser use in the 1960s and 1970s. The increased inputs of fertilisers led to increased intensification of grassland with a doubling of grass yield and of grazing animal numbers, from about 3 million to over 6 million livestock units. There is little information on relative contribution of increased chemical fertiliser use compared to increased grazing animal numbers on phosphorus loss to water. The main objective of this study was to obtain information on nutrient loss, particularly phosphorus, in overland flow from cut and grazed grassland plots, with a range of soil test phosphorus levels over three years and implications.Environmental Protection Agenc

Effect of catheter ablation on quality of life in patients with atrial fibrillation and its correlation with arrhythmia outcome

Objective To assess the effect of catheter ablation on atrial fibrillation (AF) symptoms and quality of life (QoL). Methods Patients with AF scheduled for ablation were recruited. Pulmonary vein isolation (PVI) was performed and complex fractionated atrial electrogram (CFAE)±linear ablation undertaken in patients in AF despite PVI. QoL and AF symptoms were assessed using SF-36 V2 and Atrial Fibrillation Effect on Quality-of-Life (AFEQT) questionnaires before and 3 months after ablation. Change in QoL scores after ablation was correlated with clinical parameters and the extent of ablation. Magnitude of QoL change was compared between AFEQT and SF-36 physical component summary (PCS) and mental component summary (MCS) scores and correlated with arrhythmia outcome. Results 80 patients were studied. Summative and individual health scores for both AFEQT (51.5±22.0 vs 81.3±18.2; p<0.01) and SF-36 (PCS 43.3±10.5 vs 47.9±11.3; p<0.01 and MCS 45.0±11.5 vs 51.5±9.4; p<0.01) improved significantly in patients who maintained sinus rhythm after ablation, but not in those with recurrent AF. Improvement in AFEQT (25.4±19) was significantly greater than change in PCS (6.8±6.4; p<0.01) and MCS (8.5±7.9; p<0.01) scores and correlated more closely with arrhythmia outcome (AFEQT r=0.55; PCS r=0.26; MCS r=0.30). Conclusions Patients who maintained sinus rhythm after ablation had a significant improvement in AF symptoms and QoL; however, no improvement was observed in patients with recurrent AF. QoL change after ablation did not correlate with baseline clinical parameters or ablation strategy. AF specific QoL scales are more responsive to change and correlate better with ablation outcome