Organic chemistry. History and mutual relations of universities of Russia

© 2017, Pleiades Publishing, Ltd. The review describes the history of development of organic chemistry in higher schools of Russia over a period of 170 years, since the emergence of organic chemistry in our country till now

Modern Trends of Organic Chemistry in Russian Universities

© 2018, Pleiades Publishing, Ltd. This review is devoted to the scientific achievements of the departments of organic chemistry in higher schools of Russia within the past decade

Porphyrazines with Annulated Diazepine Rings, 1. Synthesis and Characterization of Tetrakis-2,3-(5,7-diphenyl-6H-1,4-diazepino)porphyrazine and Its MgII, CuII, and ZnII Complexes - X-ray Crystal Structure of 2,3-Dicyano-5,7-diphenyl-6H-1,4-diazepine

A new class of porphyrazine macrocycles carrying peripheral diazepine rings, i.e. tetrakis-2,3-(5,7-diphenyl-6H-1-4-diazepino)porphyrazine [Ph(2)DzPzH(2)](H2O)(4), and its metal derivatives of formula [Ph(2)DzPzH(2)](H2O)(x=2-7) [M = Mg-II(H2O), Cu-II, Zn-II] have been prepared and characterized. Single crystal X-ray work on the monomeric precursor 5,7-diphenyl-2,3 -dicyano-6H-1,4-diazepine, Ph-2(CN)(2)Dz, and NMR spectra (CDCl3, (CD3)(2)SO) and UV/Vis spectra in solution of different media (basic, neutral, acid) of the monomer and its macrocyclic derivatives have provided information on the conformational flexibility of the diazepine ring as well as on the structural and electronic features of the entire porphyrazine skeleton

Tetra-2,3-Pyrazinoporphyrazines with Externally Appended Pyridine Rings 22 Synthesis, Physicochemical and Photoactivity Studies on In(III) Mono-and Heteropentanuclear Complexes

The basic macrocyclic octapyridinotetrapyrazinoporphyrazine InIII complex of formula [Py8TPyzPzIn(OAc)]·8H2O, prepared by reaction of the free ligand [Py8TPyzPzH2]·2H2O with In(OAc)3, is a stable-to-air species of which the structure has been studied by its X-ray powder diffrac-tion and mass spectra and characterization operated by IR and UV-visible spectral behavior. The complex has been further examined and proven to be of potential interest for its response as an anticancer agent in the field of photodynamic therapy (PDT), the value of Φ∆ = 0.55 (in DMF) being in the range of 0.4–0.6 at the level of similar phthalocyanine and porphyrazine analogs and qualifying the species as a highly efficient anticancer agent. Planned parallel types of investigation, including their photoactive behaviour in PDT, have been extended to the mononuclear octacation [(2-Mepy)8TPyzPzIn(OAc)]8+ (salted by iodide ions) and the heteropentanuclear derivatives [(M’Cl2)4Py8TPyzPzIn(OAc)]·xH2O (M’ = PdII, x = 8; PtII, x = 1)) and [{(Pd(CBT)2)4 }Py8TPyzPzIn(OAc)]·19H2O (CBT = m-carborane-1-thiolate anion)