8,555 research outputs found

    The University of New Hampshire Open Educational Resources Survey

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    The University of New Hampshire Survey Center conducted a survey of UNH faculty members about their usage, understanding, and needs from the University\u27s Open Educational Resources (OER) program. An email invitation to complete the internet survey was sent to one thousand eight hundred and eighty-eight (1,888) UNH faculty members in March 2017. Overall, 437 faculty members responded to the survey, yielding a response rate of 23%. This report includes figures summarizing the survey results; detailed tabular results may be found in Appendix A, Appendix B contains the open-ended responses, and Appendix C contains the survey instrument

    Biotechnology Process Patents: Is Special Legislation Needed?

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    The authors review administrative and court decisions prompting proposed changes to the patent law. After reviewing pros and cons, they argue that, on balance, pending bills can easily cause more problems than they solve

    Regulating Mobile Mental Health Apps

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    Mobile medical apps (MMAs) are a fast‐growing category of software typically installed on personal smartphones and wearable devices. A subset of MMAs are aimed at helping consumers identify mental states and/or mental illnesses. Although this is a fledgling domain, there are already enough extant mental health MMAs both to suggest a typology and to detail some of the regulatory issues they pose. As to the former, the current generation of apps includes those that facilitate self‐assessment or self‐help, connect patients with online support groups, connect patients with therapists, or predict mental health issues. Regulatory concerns with these apps include their quality, safety, and data protection. Unfortunately, the regulatory frameworks that apply have failed to provide coherent risk‐assessment models. As a result, prudent providers will need to progress with caution when it comes to recommending apps to patients or relying on app‐generated data to guide treatment

    Orthonormal Polynomials on the Unit Circle and Spatially Discrete Painlev\'e II Equation

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    We consider the polynomials ϕn(z)=Îșn(zn+bn−1zn−1+>...)\phi_n(z)= \kappa_n (z^n+ b_{n-1} z^{n-1}+ >...) orthonormal with respect to the weight exp⁥(λ(z+1/z))dz/2πiz\exp(\sqrt{\lambda} (z+ 1/z)) dz/2 \pi i z on the unit circle in the complex plane. The leading coefficient Îșn\kappa_n is found to satisfy a difference-differential (spatially discrete) equation which is further proved to approach a third order differential equation by double scaling. The third order differential equation is equivalent to the Painlev\'e II equation. The leading coefficient and second leading coefficient of ϕn(z)\phi_n(z) can be expressed asymptotically in terms of the Painlev\'e II function.Comment: 16 page

    Giant Gamma-ray Bubbles from Fermi-LAT: AGN Activity or Bipolar Galactic Wind?

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    Data from the Fermi-LAT reveal two large gamma-ray bubbles, extending 50 degrees above and below the Galactic center, with a width of about 40 degrees in longitude. The gamma-ray emission associated with these bubbles has a significantly harder spectrum (dN/dE ~ E^-2) than the IC emission from electrons in the Galactic disk, or the gamma-rays produced by decay of pions from proton-ISM collisions. There is no significant spatial variation in the spectrum or gamma-ray intensity within the bubbles, or between the north and south bubbles. The bubbles are spatially correlated with the hard-spectrum microwave excess known as the WMAP haze; the edges of the bubbles also line up with features in the ROSAT X-ray maps at 1.5-2 keV. We argue that these Galactic gamma-ray bubbles were most likely created by some large episode of energy injection in the Galactic center, such as past accretion events onto the central massive black hole, or a nuclear starburst in the last ~10 Myr. Dark matter annihilation/decay seems unlikely to generate all the features of the bubbles and the associated signals in WMAP and ROSAT; the bubbles must be understood in order to use measurements of the diffuse gamma-ray emission in the inner Galaxy as a probe of dark matter physics. Study of the origin and evolution of the bubbles also has the potential to improve our understanding of recent energetic events in the inner Galaxy and the high-latitude cosmic ray population.Comment: 46 pages, 28 figures, accepted by Ap

    Current moments of 1D ASEP by duality

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    We consider the exponential moments of integrated currents of 1D asymmetric simple exclusion process using the duality found by Sch\"utz. For the ASEP on the infinite lattice we show that the nnth moment is reduced to the problem of the ASEP with less than or equal to nn particles.Comment: 13 pages, no figur

    Different evolutionary pathways underlie the morphology of wrist bones in hominoids

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    BACKGROUND The hominoid wrist has been a focus of numerous morphological analyses that aim to better understand long-standing questions about the evolution of human and hominoid hand use. However, these same analyses also suggest various scenarios of complex and mosaic patterns of morphological evolution within the wrist and potentially multiple instances of homoplasy that would benefit from require formal analysis within a phylogenetic context.We identify morphological features that principally characterize primate - and, in particular, hominoid (apes, including humans) - wrist evolution and reveal the rate, process and evolutionary timing of patterns of morphological change on individual branches of the primate tree of life. Linear morphological variables of five wrist bones - the scaphoid, lunate, triquetrum, capitate and hamate - are analyzed in a diverse sample of extant hominoids (12 species, 332 specimens), Old World (8 species, 43 specimens) and New World (4 species, 26 specimens) monkeys, fossil Miocene apes (8 species, 20 specimens) and Plio-Pleistocene hominins (8 species, 18 specimens). RESULT Results reveal a combination of parallel and synapomorphic morphology within haplorrhines, and especially within hominoids, across individual wrist bones. Similar morphology of some wrist bones reflects locomotor behaviour shared between clades (scaphoid, triquetrum and capitate) while others (lunate and hamate) indicate clade-specific synapomorphic morphology. Overall, hominoids show increased variation in wrist bone morphology compared with other primate clades, supporting previous analyses, and demonstrate several occurrences of parallel evolution, particularly between orangutans and hylobatids, and among hominines (extant African apes, humans and fossil hominins). CONCLUSIONS Our analyses indicate that different evolutionary processes can underlie the evolution of a single anatomical unit (the wrist) to produce diversity in functional and morphological adaptations across individual wrist bones. These results exemplify a degree of evolutionary and functional independence across different wrist bones, the potential evolvability of skeletal morphology, and help to contextualize the postcranial mosaicism observed in the hominin fossil record

    From Random Matrices to Stochastic Operators

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    We propose that classical random matrix models are properly viewed as finite difference schemes for stochastic differential operators. Three particular stochastic operators commonly arise, each associated with a familiar class of local eigenvalue behavior. The stochastic Airy operator displays soft edge behavior, associated with the Airy kernel. The stochastic Bessel operator displays hard edge behavior, associated with the Bessel kernel. The article concludes with suggestions for a stochastic sine operator, which would display bulk behavior, associated with the sine kernel.Comment: 41 pages, 5 figures. Submitted to Journal of Statistical Physics. Changes in this revision: recomputed Monte Carlo simulations, added reference [19], fit into margins, performed minor editin

    Proofs of Two Conjectures Related to the Thermodynamic Bethe Ansatz

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    We prove that the solution to a pair of nonlinear integral equations arising in the thermodynamic Bethe Ansatz can be expressed in terms of the resolvent kernel of the linear integral operator with kernel exp(-u(theta)-u(theta'))/cosh[(1/2)(theta-theta')]Comment: 16 pages, LaTeX file, no figures. Revision has minor change
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