1,257 research outputs found

    QCD and electroweak corrections to WZ scattering at the LHC

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    We present the first computation of the full next-to-leading-order QCD and electroweak corrections to the WZ scattering process at the LHC. All off-shell, gauge-boson-decay, and interference effects are taken into account for the process ppμ+μe+νejj+X\mathrm{p} \mathrm{p} \to \mu^+\mu^-\mathrm{e}^+\nu_\mathrm{e} \mathrm{j} \mathrm{j} + X at the orders O(αsα6)\mathcal{O}{\left( \alpha_\mathrm{s} \alpha^6 \right)} and O(α7)\mathcal{O}{\left( \alpha^7 \right)}. The electroweak corrections feature the typical Sudakov behaviour towards high energy and amount to 16%-16\% relative to the electroweak contribution to the integrated cross section. Moreover, the corrections induce significant shape distortions in differential distributions. The next-to-leading-order analysis of the quark- and gluon-induced channels is supplemented by a leading-order study of all possible contributions to the full 4\ell+2\mbox{jets} production cross section in a realistic fiducial phase-space volume

    Electrical properties of breast cancer cells from impedance measurement of cell suspensions

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    Impedance spectroscopy of biological cells has been used to monitor cell status, e.g. cell proliferation, viability, etc. It is also a fundamental method for the study of the electrical properties of cells which has been utilised for cell identification in investigations of cell behaviour in the presence of an applied electric field, e.g. electroporation. There are two standard methods for impedance measurement on cells. The use of microelectrodes for single cell impedance measurement is one method to realise the measurement, but the variations between individual cells introduce significant measurement errors. Another method to measure electrical properties is by the measurement of cell suspensions, i.e. a group of cells within a culture medium or buffer. This paper presents an investigation of the impedance of normal and cancerous breast cells in suspension using the Maxwell-Wagner mixture theory to analyse the results and extract the electrical parameters of a single cell. The results show that normal and different stages of cancer breast cells can be distinguished by the conductivity presented by each cell. © 2010 IOP Publishing Ltd

    Correcting the polarization effect in low frequency Dielectric Spectroscopy

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    We demonstrate a simple and robust methodology for measuring and analyzing the polarization impedance appearing at interface between electrodes and ionic solutions, in the frequency range from 1 to 10610^6 Hz. The method assumes no particular behavior of the electrode polarization impedance and it only makes use of the fact that the polarization effect dies out with frequency. The method allows a direct and un-biased measurement of the polarization impedance, whose behavior with the applied voltages and ionic concentration is methodically investigated. Furthermore, based on the previous findings, we propose a protocol for correcting the polarization effect in low frequency Dielectric Spectroscopy measurements of colloids. This could potentially lead to the quantitative resolution of the α\alpha-dispersion regime of live cells in suspension

    Triclinic modification of N-[(1,1-di­methyl­ethoxy)carbon­yl]-3-[(R)-prop-2-en-1-ylsulfin­yl]-(R)-alanine ethyl ester at 120 (1) K

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    There are two independent mol­ecules in the asymmetric unit of the title compound, C13H23NO5S. In the crystal structure, inter­molecular N—H⋯O hydrogen bonds link mol­ecules into two independent one-dimensional chains along [100]. The crystal studied was found to be a non-merohedral twin with a ratio of 0.615 (6):0.385 (1) for the refined components. At 200 (1) K [Singh et al. (2009 ▶). Acta Cryst. E65, o1385–o1386] the crystal structure of the title compound contains one disordered mol­ecule in the asymmetric unit of a monoclinic unit cell

    Sterilization of lung matrices by supercritical carbon dioxide

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    Lung engineering is a potential alternative to transplantation for patients with end-stage pulmonary failure. Two challenges critical to the successful development of an engineered lung developed from a decellularized scaffold include (i) the suppression of resident infectious bioburden in the lung matrix, and (ii) the ability to sterilize decellularized tissues while preserving the essential biological and mechanical features intact. To date, the majority of lungs are sterilized using high concentrations of peracetic acid (PAA) resulting in extracellular matrix (ECM) depletion. These mechanically altered tissues have little to no storage potential. In this study, we report a sterilizing technique using supercritical carbon dioxide (ScCO(2)) that can achieve a sterility assurance level 10(−6) in decellularized lung matrix. The effects of ScCO(2) treatment on the histological, mechanical, and biochemical properties of the sterile decellularized lung were evaluated and compared with those of freshly decellularized lung matrix and with PAA-treated acellular lung. Exposure of the decellularized tissue to ScCO(2) did not significantly alter tissue architecture, ECM content or organization (glycosaminoglycans, elastin, collagen, and laminin), observations of cell engraftment, or mechanical integrity of the tissue. Furthermore, these attributes of lung matrix did not change after 6 months in sterile buffer following sterilization with ScCO(2), indicating that ScCO(2) produces a matrix that is stable during storage. The current study's results indicate that ScCO(2) can be used to sterilize acellular lung tissue while simultaneously preserving key biological components required for the function of the scaffold for regenerative medicine purposes

    Digital sound absorbing metafluid inspired by cereal straws

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    International audienceUsed as building biomaterials for centuries, cereal straws are known for their remarkable acoustic performances in sound absorption. Yet, their use as fibrous media disregards their internal structure made of nodes partitioning stems. Here, we show that such nodes can impart negative acoustic bulk modulus to straw balls when straws are cut on either side of a node. Such metafluid inspired by cereal straws combines visco-thermal diffusion with strong wave dispersion arising from quarter-wavelength resonances within straws. Large spectral bandgaps and slow sound regimes are theoretically predicted and experimental data from impedance tube measurements on an idealised 3D-printed sample layer are in good agreement with the theoretical model. Perfect absorption is achieved at wavelengths 13 times larger than the thickness of the metafluid layer, and slow sound entails an increased density of states causing a cascade of high absorption peaks. Such features could lead cereal straws to serve as cheap acoustic bio-metamaterials

    The prolate-to-oblate shape transition of phospholipid vesicles in response to frequency variation of an AC electric field can be explained by the dielectric anisotropy of a phospholipid bilayer

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    The external electric field deforms flaccid phospholipid vesicles into spheroidal bodies, with the rotational axis aligned with its direction. Deformation is frequency dependent: in the low frequency range (~ 1 kHz), the deformation is typically prolate, while increasing the frequency to the 10 kHz range changes the deformation to oblate. We attempt to explain this behaviour with a theoretical model, based on the minimization of the total free energy of the vesicle. The energy terms taken into account include the membrane bending energy and the energy of the electric field. The latter is calculated from the electric field via the Maxwell stress tensor, where the membrane is modelled as anisotropic lossy dielectric. Vesicle deformation in response to varying frequency is calculated numerically. Using a series expansion, we also derive a simplified expression for the deformation, which retains the frequency dependence of the exact expression and may provide a better substitute for the series expansion used by Winterhalter and Helfrich, which was found to be valid only in the limit of low frequencies. The model with the anisotropic membrane permittivity imposes two constraints on the values of material constants: tangential component of dielectric permittivity tensor of the phospholipid membrane must exceed its radial component by approximately a factor of 3; and the membrane conductivity has to be relatively high, approximately one tenth of the conductivity of the external aqueous medium.Comment: 17 pages, 6 figures; accepted for publication in J. Phys.: Condens. Matte

    Electrode Polarization Effects in Broadband Dielectric Spectroscopy

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    In the present work, we provide broadband dielectric spectra showing strong electrode polarization effects for various materials, belonging to very different material classes. This includes both ionic and electronic conductors as, e.g., salt solutions, ionic liquids, human blood, and colossal-dielectric-constant materials. These data are intended to provide a broad data base enabling a critical test of the validity of phenomenological and microscopic models for electrode polarization. In the present work, the results are analyzed using a simple phenomenological equivalent-circuit description, involving a distributed parallel RC circuit element for the modeling of the weakly conducting regions close to the electrodes. Excellent fits of the experimental data are achieved in this way, demonstrating the universal applicability of this approach. In the investigated ionically conducting materials, we find the universal appearance of a second dispersion region due to electrode polarization, which is only revealed if measuring down to sufficiently low frequencies. This indicates the presence of a second charge-transport process in ionic conductors with blocking electrodes.Comment: 9 pages, 6 figures, experimental data are provided in electronic form (see "Data Conservancy"
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