On Extensions of Superconformal Algebras

Starting from vector fields that preserve a differential form on a Riemann sphere with Grassmann variables, one can construct a Superconformal Algebra by considering central extensions of the algebra of vector fields. In this note, the N=4 case is analyzed closely, where the presence of weight zero operators in the field theory forces the introduction of non-central extensions. How this modifies the existing Field Theory, Representation Theory and Gelfand-Fuchs constructions is discussed. It is also discussed how graded Riemann sphere geometry can be used to give a geometrical description of the central charge in the N=1 theory.Comment: 16 Pages, LaTeX2e, references added, typesetting fixed, Journal ref adde

MAVERICK: A Synthetic Murder Mystery Network Dataset to Support Sensemaking Research

AbstractThe MAVERICK dataset was created to support a series of empirical studies looking at the effectiveness of network visualizations intended to support information foraging and human sensemaking within the domain of counterinsurgency intelligence analysis. This synthetic dataset is structured as a forensic mystery with the central goal of solving a fictional murder. The dataset includes 181 text-based reports, with additional media included with some messages as attachments, collected from various sources of varying reliability. The reports are framed as being collected from the perspective of a reporter investigating the murder through interviews with suspects and observations taken at the site the murder. The dataset includes intentional and unintentional deception along with calculated source reliabilities based on available evidence. The dataset is dynamic in nature, as the information in the dataset evolves and expands over a simulated period of time. This is done to both to simulate a real-world scenario, and to allow for evolutionary tasks and experiments to be performed using the dataset. The dataset is designed to be complex enough to simulate a real-world, while remaining accessible to individuals without experience in a specific domain of interest. This meant that it had to be on a topic that did not require prior domain knowledge to understand available information or to understand what strategies should be applied during analysis of the dataset. The solution to these challenges was the development of a fictional murder mystery. The plot involves a murder that took place over the course of a weekend with several possible suspects at a large private estate. This scenario allowed for a great deal of complexity; however, it was also a subject matter that could be easily understood by participants without prerequisite domain experience

The effect of photodynamic therapy on oral-premalignant lesions : a systematic review

Dentists now have access to a wide range of unique treatment methods as a result of substantial scientific and technological breakthroughs in the field of dentistry. Photodynamic therapy (PDT) is a non-invasive treatment procedure that use photosensitize

Microscale Modeling of High-Temperature Heat Transfer in Anisotropic Porous Materials

No abstract availabl

Role of anisotropic impurity scattering in anisotropic superconductors

A theory of nonmagnetic impurities in an anisotropic superconductor including the effect of anisotropic (momentum-dependent) impurity scattering is given. It is shown that for a strongly anisotropic scattering the reduction of the pair-breaking effect of the impurities is large. For a significant overlap between the anisotropy functions of the scattering potential and that of the pair potential and for a large amount of anisotropic scattering rate in impurity potential the superconductivity becomes robust vis a vis impurity concentration. The implications of our result for YBCO high-temperature superconductor are discussed.Comment: 14 pages, RevTeX, 5 PostScript figures, to be published in Phys. Rev. B (December 1, 1996

Role of Endoscopic Retrograde Cholangiography and Nasobiliary Drainage in the Management of Postoperative Biliary Leak

In order to assess the role of endoscopic retrograde cholangiography in evaluating the patients with post-operative biliary leak and of endoscopic nasobiliary drainage in its management, 36 patients with biliary leak seen over a period of 9 years were studied. Thirty-two had biliary leak following cholecystectomy, 3 following repair of liver trauma and 1 following choledochoduodenostomy. Patients presented at an interval of 4 days to 210 days (mean ± SEM, 32.4 ± 6.7 days) following laparotomy. Hyperbilirubinemia was noticed in only 13 patients (36.1%), while abdominal ultrasonogram showed ascites or biloma in 24 (66.7%). Endoscopic retrograde cholangiography showed the leak to involve the common bile duct in 55.6%, cystic duct in 33.3% and intrahepatic biliary radicles in 8.3%. Associated lesions included bile duct obstruction due to stricture or accidental ligature in 20%, bile duct stone in 20% and liver abscess in 2.8%

Reproductive outcomes from ten years of elective oocyte cryopreservation

Research question: To assess the relationship between the number of oocytes retrieved during elective oocyte cryopreservation (EOC) cycles with various clinical, biochemical, and radiological markers, including age, body mass index (BMI), baseline anti-Müllerian hormone (AMH), antral follicle count (AFC), Oestradiol level (E2) and total number of follicles ≥ 12 mm on the day of trigger. To also report the reproductive outcomes from women who underwent EOC. Methods: A retrospective cohort of 373 women embarking on EOC and autologous oocyte thaw cycles between 2008 and 2018 from a single London clinic in the United Kingdom. Results: 483 stimulation cycles were undertaken amongst 373 women. The median (range) age at cryopreservation was 38 (26–47) years old. The median numbers of oocytes retrieved per cycle was 8 (0–37) and the median total oocytes cryopreserved per woman was 8 (0–45). BMI, E2 level and number of follicles ≥ 12 mm at trigger were all significant predictors of oocyte yield. Multivariate analysis confirmed there was no significant relationship between AFC or AMH, whilst on univariate analysis statistical significance was proven. Thirty six women returned to use their cryopreserved oocytes, of which there were 41 autologous oocyte thaw cycles undertaken. There were 12 successful livebirths achieved by 11 women. The overall livebirth rate was 26.8% per cycle. No livebirths were achieved in women who underwent EOC ≥ 40 years old, and 82% of all livebirths were achieved in women who had done so between 36 and 39 years old. Conclusion: Clinical, biochemical and radiological markers can predict oocyte yield in EOC cycles. Reproductive outcomes are more favourable when cryopreservation is performed before the age of 36, with lower success rates of livebirth observed in women aged 40 years and above

Psychophysical Investigations into the Role of Low-Threshold C Fibres in Non-Painful Affective Processing and Pain Modulation

We recently showed that C low-threshold mechanoreceptors (CLTMRs) contribute to touch-evoked pain (allodynia) during experimental muscle pain. Conversely, in absence of ongoing pain, the activation of CLTMRs has been shown to correlate with a diffuse sensation of pleasant touch. In this study, we evaluated (1) the primary afferent fibre types contributing to positive (pleasant) and negative (unpleasant) affective touch and (2) the effects of tactile stimuli on tonic muscle pain by varying affective attributes and frequency parameters. Psychophysical observations were made in 10 healthy participants. Two types of test stimuli were applied: stroking stimulus using velvet or sandpaper at speeds of 0.1, 1.0 and 10.0 cm/s; focal vibrotactile stimulus at low (20 Hz) or high (200 Hz) frequency. These stimuli were applied in the normal condition (i.e. no experimental pain) and following the induction of muscle pain by infusing hypertonic saline (5%) into the tibialis anterior muscle. These observations were repeated following the conduction block of myelinated fibres by compression of sciatic nerve. In absence of muscle pain, all participants reliably linked velvet-stroking to pleasantness and sandpaper-stroking to unpleasantness (no pain). Likewise, low-frequency vibration was linked to pleasantness and high-frequency vibration to unpleasantness. During muscle pain, the application of previously pleasant stimuli resulted in overall pain relief, whereas the application of previously unpleasant stimuli resulted in overall pain intensification. These effects were significant, reproducible and persisted following the blockade of myelinated fibres. Taken together, these findings suggest the role of low-threshold C fibres in affective and pain processing. Furthermore, these observations suggest that temporal coding need not be limited to discriminative aspects of tactile processing, but may contribute to affective attributes, which in turn predispose individual responses towards excitatory or inhibitory modulation of pain

Observation of Ground-State Two-Neutron Decay

Neutron decay spectroscopy has become a successful tool to explore nuclear properties of nuclei with the largest neutron-to-proton ratios. Resonances in nuclei located beyond the neutron dripline are accessible by kinematic reconstruction of the decay products. The development of two-neutron detection capabilities of the Modular Neutron Array (MoNA) at NSCL has opened up the possibility to search for unbound nuclei which decay by the emission of two neutrons. Specifically this exotic decay mode was observed in 16Be and 26O.Comment: To be published in Acta Physica Polonica