744 research outputs found

    Comparative Analysis Of Employee Job Satisfaction In The Accounting Profession

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    Evaluating job satisfaction among accounting professionals is an increasingly important area of concern for employers, which strive to recruit and retain quality employees and to improve their competitive positions. This study examines the results of surveys of accounting graduates from two AACSB International accredited universities from 1980 to 2003. Respondents were asked a variety of questions on job satisfaction as it relates to many factors including profession, firm size, certification, age, sex, race, advanced degrees and parent education. The findings of this study on job satisfaction provide benchmarks upon which accounting firms can use to evaluate job satisfaction levels among their own employees

    Natriuretic peptide receptors regulate cytoprotective effects in a human ex vivo 3D/bioreactor model

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    © 2013 Peake et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

    Clinical Use of Cinacalcet in MEN1 Hyperparathyroidism

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    Background. Management of multiple-endocrine neoplasia type 1- (MEN1-) associated hyperparathyroidism is associated with high recurrence rates and high surgical morbidity due to multiple neck explorations. Cinacalcet, a calcimimetic agent licensed for the treatment of secondary hyperparathyroidism and parathyroid carcinoma, may provide a medical alternative for the management of these complex patients. Methods. A prospective audit was performed of eight patients; three males and five females, aged 20–38 at diagnosis. Two patients commenced cinacalcet as primary treatment and six had previous surgery. Six patients had complications of hyperparathyroidism: renal calculi, renal dysfunction, and reduced bone mineral density. All were commenced on cinacalcet 30 mg bd for MEN1 associated hyperparathyroidism; doses were subsequently reduced to 30 mg od in four patients. Results. Significant reductions were observed in serum calcium and PTH measurements. Serum calcium reduced by a median of 0.35 mmol/L (P = .012 Wilcoxon Signed Rank). Serum PTH levels decreased by a median of 5.05 pmol/L (P = .012). There was no change in urine calcium. Duration ranged from 10–35 months with maintenance of control. Cinacalcet was well tolerated by six patients; one experienced nausea and one experienced diarrhoea. Conclusion. Cinacalcet is an effective and well-tolerated medical treatment for the management of complex primary hyperparathyroidism
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